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It was a disconcerting sight: Sean Strickland, with his hands low and a sheepish look across his face, shuffling towards one of the most devastating punchers in the UFC. There is no ‘but’ to follow; Alex Pereira swatted the American down to a knee with a signature left hook, Strickland’s arms flailing helplessly before he stood up into a right cross, which sent him cascading dangerously to the canvas. The manner of this demise at the heavy hands of the Brazilian brought to mind a mythical image: that of a lemming wandering mindlessly off a cliff. Yet Strickland’s approach until that point had actually been understandable – not as understandable as grappling with Pereira, as most expected him to, but sensible in a certain sense. The southpaw was pressing forward relentlessly with constant output, fighting behind a jolting jab, trying to prevent Pereira from setting his feet to muster power. Pereira, however, exploited Strickland’s reflexes. With kicks and jabs to the body, Pereira gradually lured Strickland’s habitual parries away from his head. Then, with one subtle, feinted crouch, Pereira created space to curve a left hook onto the chin of the American. With that, Strickland was undone – as was his six-fight win streak, which had stretched from 2022 back to 2018. In his next fight, the 32-year-old was again beaten, losing a split decision to Jared Cannonier. Just a few weeks prior, Pereira had stopped champion Israel Adesanya against the fence, moving to 3-0 overall against his old kickboxing rival, despite the latter’s vast experiential advantage in MMA. Adesanya would bounce back five months later, regaining the middleweight title at the first attempt with his own knockout of Pereira, who would make a quick turnaround with a successful debut at light-heavyweight in July. All the while, Strickland followed the examples set by Adesanya and Pereira, bouncing back with a victory; two, in fact. First, the controversial, outspoken American would outpoint Nassourdine Imavov in January, stepping in as a late-notice replacement. Then, in July, Strickland proved wrong many fans by stopping Abus Magomedov in the second round, before making an impassioned callout of Adesanya – whom he has mocked regularly in recent years, from a distance and from mere metres away. Still, the UFC seemed set to overlook Strickland, who once expressed his desire to ‘kill’ an opponent someday (not that they would have overlooked him because of that or any kind of controversial comment, based on past cases). “If I killed somebody in the ring, it’d f***ing make me very happy,” he said in 2021, demonstrating that he is better at employing his fists – and he is often criticised for that ability, even – than using any filter. “Like, if Uriah [Hall] hits me and maybe I have a brain aneurysm and die, you’ll hear me saying: ‘I’m okay, that’s a good death.’ We’re all going to die sometime. You know, might as well end in a good way. We’re all going to the same place, man. It’s either gonna be then or now. Just enjoy it.” Meanwhile, his teasing of Adesanya, who is as flamboyant outside the ring as he is in it, has relied heavily on outdated jibes with an uncomfortable undertone. In response to one recurring slight, Adesanya has vowed to knock out Strickland with fists adorned with painted nails. And the Nigerian-New Zealander, 34, will get the chance to do that on Saturday, when he defends his middleweight title in the main event of UFC 293 in Sydney. For Strickland’s campaign to fight Adesanya eventually paid off, specifically when Dricus Du Plessis – towards whom the champion holds a grave grudge – was taken out of the title picture due to injury. Adesanya vs Du Plessis may yet come to pass, and if it does, Adesanya will likely have more harsh words for the South African, at whom he has already lashed out viciously. It is worth noting at this point that Adesanya himself has gotten away with distasteful comments before, and that many fans believe he has misconstrued certain points made by Du Plessis. In any case, first up for him is Strickland. Adesanya has been the betting favourite in all but one of his UFC bouts, even his rematch with Pereira, and that is no different against Strickland. The “Last Stylebender” is expected to dissect and damage his challenger at will. While Adesanya possesses less power than Pereira, he is an even more dynamic striker than the Brazilian, and he can employ the kind of counter-strikes that Strickland risks walking straight into – if the latter’s approach against Pereira is anything to go by. Adesanya’s fans are excited by that prospect. Many of Strickland’s fans have been more enthused by the verbal warfare than the impending physical warfare. Some have forgiven Strickland for certain comments due to his recollections of a concerning, upsetting relationship with his late father. Adesanya, who lives for nights and atmospheres like Saturday’s in Sydney, will not allow himself to forgive Strickland for a single word. The champion has always harnessed anything and everything to hype himself up for a title showdown. The build to UFC 293 has already threatened to turn ugly. Adesanya, famed for his beautifully destructive performances, will hope to turn things ugly for Strickland when the cage door closes. Read More Adesanya vs Strickland live stream: How to watch UFC 293 online and on TV this weekend Jared Cannonier revealed as back-up fighter for Adesanya vs Strickland at UFC 293 Conor McGregor finally receives black belt in jiu-jitsu Back-up fighter revealed for Adesanya vs Strickland at UFC 293 Mark Zuckerberg trains with UFC champions on speedboat UFC 293 card in full as Adesanya defends title against Strickland this weekend

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Infertility is a problem that afflicts more than a billion people across the world, which is why treatments such as IVF are so important. The procedure (in vitro fertilisation, to use it’s full name) involves the extraction of an egg from the woman's ovaries to be fertilised with sperm in a laboratory and returned to the woman’s womb. The goal is that the resulting embryo will then grow and develop into a foetus, blessing the parent or parents with a baby. However, success rates for IVF – as in, the percentage of treatments that result in a live birth – remain somewhat unencouraging: 32 per cent for women aged under 35; 25 per cent for women aged 35 to 37, with the numbers continuing to drop the older you get, according to the NHS. Nevertheless, a major new study has revealed a striking new finding which could help boost the hopes of countless aspiring mums and dads across the world. Sign up for our free Indy100 weekly newsletter After analysing 3,657 frozen embryos over a period of eight years, researchers in Western Australia found that IVF was much more likely to work when eggs had been harvested in the summer. The team clarified that it didn’t seem to matter when the embryos were transferred to the mother’s womb, just when the eggs were collected. Indeed, the likelihood of babies being born when the eggs had been retrieved in the summer was 30 per cent higher than when they had been retrieved in the autumn, according to the scientists. The team also found that the temperature on the day of egg collection didn’t seem to have an impact on success rates, but the number of sunny hours did. Of the embryos they tested, those harvested on days that had the most sunshine were 28 per cent more likely to result in a live birth compared to the darkest and most overcast days. “Our study suggests that the best conditions for live births appear to be associated with summer and increased sunshine hours on the day of egg retrieval,” the study’s lead, Dr Sebastian Leathersich, of Perth’s King Edward Memorial Hospital, said about the paper, which was published in the journal Human Reproduction. Still, he noted: “There are many factors that influence fertility treatment success, age being among the most important. “However, this study adds further weight to the importance of environmental factors and their influence on egg quality and embryonic development." He further explained: “We effectively separated the conditions at the time of egg collection from the conditions at the time of transfer, demonstrating that environmental factors when the eggs are developing are as, if not more, important than environmental factors during implantation and early pregnancy.” The expert obstetrician and gynaecologist added: “Optimising factors such as avoiding smoking, alcohol and other toxins and maintaining healthy activity levels and weight should be paramount. However, clinicians and patients could also consider external factors such as environmental conditions.” Despite Dr Leathersich and his colleagues concluding that the temperature on the day of egg collection had little bearing on the success of the process, they also found that the temperature on the day of embryo implantation did make a difference. The chances of a live birth rate decreased by 18 per cent when the embryos were transferred on the hottest days (when average temperatures measured between 14.5C and 27.8C) compared to the coolest days (0.1C to 9.8C), and there was a small increase in miscarriage rates, from 5.5 per cent to 7.6. The finding that miscarriage rates were highest when embryo transfer took place on the hottest days is consistent with other studies showing higher rates of miscarriage in the summer months. “This suggests that the negative effects of high temperature are more likely related to early pregnancy rather than egg development,” Dr Leathersich concluded. When it comes to the disparity in success rates between eggs retrieved in summer and autumn, he and his team pointed out that melatonin levels could be at play. Differences in lifestyles between the winter and summer months may also play a role, he and his colleagues acknowledged. "It is possible that there are differences in activity, diet, and lifestyle in different seasons which could underlie the observed differences in live birth rates, though such data were not collected in this study," they wrote. "It is also possible that other environmental factors, including pollutants, may impact clinical outcomes." Whilst the study’s findings are compelling, Dr Leathersich and his team admitted that it did have its limitations. The research was done in hindsight, using eggs that had been frozen, then thawed, so it could not draw watertight conclusions. “Ideally, these findings should be replicated in other sites with different conditions and different treatment protocols to confirm the findings,” Dr Leathersich said. “It would also be interesting to look at the impact of season and environmental factors on sperm parameters, as this could have contributed to our observations.” He added: “We are now planning to analyse this same group of patients using air quality data, as there may be seasonal changes in exposure to harmful pollutants which could negatively affect reproductive outcomes. “Finally, given the huge increase in so-called 'social egg freezing' for fertility preservation and the fact that this group generally have flexibility about when they choose to undergo treatment, it would be very interesting to see if these observations hold true with frozen eggs that are thawed and fertilised years later. “Any improved outcomes in this group could have big impacts for women making decisions about their future fertility, but the long-term follow-up required means it is likely to be some time before we can draw any conclusions for this population.” Have your say in our news democracy. Click the upvote icon at the top of the page to help raise this article through the indy100 rankings.

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