Cincinnati hit six home runs including Nick Martini’s three-run shot in the first inning in a 19-2 rout of the St. Louis Cardinals that kept the Reds alive in the National League wild-card race

TEL AVIV, Israel (AP) — The Israeli government’s adoption of the first part of a controversial judicial overhaul on Monday unleashed turbulence in the streets of Israel and in the halls of the Knesset.

The jury in the trial of Robert Bowers, the gunman who killed 11 worshippers and wounded six others at a Pittsburgh synagogue in 2018, is now deliberating on whether to sentence him to death.

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Ange Postecoglou is excited to see Tottenham midfielder Rodrigo Bentancur close to his best again amid a growing injury crisis at the club. Spurs host Aston Villa on Sunday with at least nine first-team players ruled out and Pape Sarr a doubt after he returned with a knock from international duty with Senegal. A much-needed positive for the Australian is the return to fitness of Bentancur, who made his first competitive start in nine months in Uruguay’s 3-0 win over Bolivia on Tuesday after a serious knee injury. With first-choice midfielders James Maddison (ankle) and Yves Bissouma (suspended) definitely absent for the visit of Villa, Bentancur could be thrust into action. “The back four is probably the major issue for us at the moment. We’re really low on depth there, but midfield as well. That’s just the period we’re going through,” Postecoglou reflected. “The fact Rodrigo got an opportunity to start (for Uruguay) is good for us. It gives him that confidence that he’s able to get through a game. “The beauty of him is he can play a couple of different areas. I think he can play as a six, he can play further forward as an eight and he’s even creative. I think he can score goals as well. “We were kind of hoping with him, Madders, Pape, Biss and people like Pierre(-Emile Hojbjerg) we were well stocked in that midfield area for different kinds of combinations, but obviously that has been disrupted a bit. “The key for Rodrigo is to get him back to that level physically and mentally where he feels really comfortable about playing at this level. “I don’t think he is far off it from what I’ve seen and again certainly over the next few weeks he will get that opportunity.” Bentancur was one of Tottenham’s best players last season and impressed in a box-to-box role before he sustained anterior cruciate ligament damage in February. Uruguay boss Marcelo Bielsa used him at the base of a midfield three on Tuesday, which is where Bissouma has played for Spurs so far this season. With Bissouma suspended for the Villa match after he picked up his fifth yellow card of the campaign at Wolves, Postecoglou hinted Bentancur could fill that void. He said: “Yeah, potentially. Watching the (Bolivia) game and how he played, he did it really well so you know he can play there. “I don’t think he is that far off from a physical perspective of being able to play his normal game, whether that is box-to-box, and part of it is getting belief in himself and his own body that he is capable of doing it.” Spurs’ hopes of returning to winning ways have been hit by their lengthy injury list, but Postecoglou insisted: “Aston Villa will be a great test for us, but we’re at home. “Apart from the Chelsea game, our home form has been really strong and we need to make sure we get back to that.” Read More LTA urges British tennis fans to show ‘respect’ after Novak Djokovic row at Davis Cup Erik ten Hag prepared for Everton to be ‘mad’ and urges Man Utd to match them Alexis Mac Allister’s performance could be key against Man City – Jan Molby PA selective guide to sport on TV for w/c November 27 Nathan Heaney eyeing middleweight world title fight against Janibek Alimkhanuly Eddie Howe sees no benefit to Newcastle over loans between associated clubs

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Scientists have developed eye scans that use artificial intelligence to detect markers of Parkinson’s disease seven years before symptoms appear, making it the first time the condition can be detected several years before diagnosis. Parkinson disease’s is a deteriorating neurological condition characterised by a reduction of dopamine. The research, published on Tuesday in the journal Neurology, used two large sets of health data – the AlzEye dataset and the UK Biobank database – to identify these subtle markers, even though Parkinson’s disease has a relatively low prevalence among this population. The AlzEye dataset was formed from the world’s largest database of retinal images and associated clinical data. Post-mortem examination of Parkinson’s patients has found differences in the retina’s inner nuclear layer (INL). Previous studies have shown eye-scan data can reveal signs of other deterioration of neurological conditions like Alzheimer’s, multiple sclerosis and schizophrenia. The studies are part of an emerging field of research called “oculomics”. Eye scan data has also been shown to reveal people’s propensity to high blood pressure, heart disease, stroke and diabetes. Doctors have historically conducted physical eye tests, believing the organ can act as a “window” to the rest of the body, and provide direct insight into many aspects of human health. With high-resolution images of the retina now a routine part of eye care, scientists said the data from these scans can be put to better analysis to gain better insights on patient health. In particular, a type of 3D scan known as optical coherence tomography (OCT) is widely used in eye clinics and by high-street opticians. These scans can produce a cross-section of the retina – the screen of nerves at the back of the eye – in incredible detail down to a thousandth of a millimetre. Images of the retina can be extremely useful for monitoring eye health. But researchers said their value can become much more as a retinal scan is the only non-intrusive way to view layers of cells below the skin’s surface. They found in the new study that a reduced thickness of these cell layers was associated with an increased risk of developing Parkinson’s disease. Scientists have also started using powerful computers and AI technology to accurately analyse large numbers of OCTs and other eye images, in a fraction of the time it would take a human. “While we are not yet ready to predict whether an individual will develop Parkinson’s, we hope that this method could soon become a pre-screening tool for people at risk of disease,” study co-author Siegfried Wagner from the University College London said. “Finding signs of a number of diseases before symptoms emerge means that, in the future, people could have the time to make lifestyle changes to prevent some conditions arising, and clinicians could delay the onset and impact of life-changing neurodegenerative disorders,” Dr Wagner said. Researchers said the OCT method used in the study is also non-invasive of lower cost, more scalable and quicker than brain scans for this purpose. Read More Study could lead to injections that replicate brain benefits of exercise Dementia breakthrough as drug treatment comes one step closer Parkinson’s therapy could be used to tackle alcohol abuse Justin Trudeau slams Facebook for blocking news stories about wildfires Microsoft makes big changes to takeover of Activision Blizzard Meta could finally launch Threads feature everyone is waiting for