Call of Duty: Warzone 2.0 servers are currently online, and fans can check server statuse by visiting Activision's website.

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F1’s highly anticipated Las Vegas Grand Prix is back on track after a disastrous opening day had to be suspended to fix a loose manhole cover, as Charles Leclerc claimed pole in qualifying on Saturday. The first session of F1’s newest event had only been going for eight minutes before Carlos Sainz’s car stopped on the lengthy Vegas strip. Replays show his Ferrari car, at speeds of over 200mph, went over a loose drain cover before the Spaniard veered to the side and stopped the car due to substantial floor damage, and Ferrari were furious. F1 grid: Starting positions for the Las Vegas Grand Prix FP2 was delayed for more than two hours while the circuit was made safe, before the Ferrari pair of Charles Leclerc and Sainz topped the timings, with Max Verstappen only sixth. FP3 then saw Mercedes’ George Russell top the charts ahead of McLaren’s Oscar Pastri and Williams’ Logan Sargeant, with Ferrari way down the results after choosing to preserve their soft tyres. But their true pace was revealed in qualifying as Leclerc and Carlos Sainz – who has a 10-place grid penalty after that FP1 incident – finished first and second, ahead of Red Bull’s Max Verstappen and Mercedes’ George Russell. But their teammates Sergio Perez and Lewis Hamilton suffered shock exits in Q2 and will start in the middle of the pack. Follow live updates from the Las Vegas Grand Prix below and check the latest F1 odds and tips here. Read More F1 grid: Starting positions for Las Vegas Grand Prix What Charles Leclerc needs to finally claim victory from pole in first Las Vegas Grand Prix Shambles and incompetence: F1 enters new Las Vegas dawn with disaster on opening night

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Using existing drugs to treat cervical cancer before standard treatment could lead to a 35% reduction in the risk of relapse or death, a new study suggests. Researchers from the UCL Cancer Institute and UCLH looked into whether a short course of induction chemotherapy (IC), where a drug is used to destroy as many cancer cells as possible, before chemoradiation (CRT), could help with this. Here’s everything you need to know about the findings… What is cervical cancer? According to the NHS website, cervical cancer is a type of cancer found anywhere near the cervix – the opening between the vagina and the womb (uterus), which is also known as the neck of the womb. Most cervical cancers grow very slowly and are caused by an infection from specific types of human papillomavirus (HPV) and mostly affect women under the age of 45. According to Jo’s Cervical Cancer Trust, symptoms include vaginal bleeding that is unusual to you, changes to vaginal discharge, discomfort during sex and pain in your lower back or pelvis. Changes to cells can be spotted by a cervical screening, and then treated before they turn into cancer. There are around 3,200 new cases every year in the UK, with the five-year survival rate being around 70%, according to Cancer Research UK. CRT has been the standard treatment for cervical cancer patients since 1999, but even though there have been overall significant developments in radiation therapy techniques, up to 30% of people experience their cancer coming back. What did the research involve? Over a 10-year period, 500 patients who had been diagnosed with cervical cancer – that was large enough to see without a microscope but hadn’t spread to other parts of the body – took part in the Interlace trial at hospitals in the UK, Mexico, India, Italy and Brazil. Researchers looked into whether a short course of IC before CRT could reduce rates of relapse and death. What results were found? After five years, researchers discovered that 80% of the people who received a combination of chemotherapy and radiotherapy were alive, whilst 73% had not seen their cancer return or spread. A major benefit, according to researchers, is that it can be incorporated into standard of care treatment relatively quickly, because cheap, accessible and already-approved ingredients such as carboplatin and paclitaxel are needed for IC. “Our trial shows that this short course of additional chemotherapy delivered immediately before the standard CRT can reduce the risk of the cancer returning or death by 35%,” said Dr Mary McCormack, lead investigator of the trial from UCL Cancer Institute and UCLH. “This is the biggest improvement in outcome in this disease in over 20 years. “I’m incredibly proud of all the patients who participated in the trial; their contribution has allowed us to gather the evidence needed to improve treatment of cervical cancer patients everywhere. “We couldn’t have done this without the generous support of Cancer Research UK.” Why is the research important? Dr Iain Foulkes, executive director of research and innovation at Cancer Research UK, said: “Timing is everything when you’re treating cancer. The simple act of adding induction chemotherapy to the start of chemoradiation treatment for cervical cancer has delivered remarkable results in this trial. “A growing body of evidence is showing the value of additional rounds of chemotherapy before other treatments like surgery and radiotherapy in several other cancers. “Not only can it reduce the chances of cancer coming back, it can be delivered quickly using drugs already available worldwide. “We’re excited for the improvements this trial could bring to cervical cancer treatment and hope short courses of induction chemotherapy will be rapidly adopted in the clinic.”

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