President Joe Biden is expected to sign legislation on Saturday to raise the debt ceiling, just two days before the U.S. Treasury warned that the country would struggle to pay its bills. The bipartisan measure, which was approved this week by the House and Senate, eliminates the potential for an unprecedented government default. “Passing this budget agreement was critical. The stakes could not have been higher," Biden said from the Oval Office on Friday evening. “Nothing would have been more catastrophic,” he said, than defaulting on the country's debt. The agreement was hashed out by Biden and House Speaker Kevin McCarthy, giving Republicans some of their demanded federal spending cuts but holding the line on major Democratic priorities. It raises the debt limit until 2025 — after the 2024 presidential election — and gives legislators budget targets for the next two years in hopes of assuring fiscal stability as the political season heats up. “No one got everything they wanted but the American people got what they needed,” Biden said, highlighting the “compromise and consensus” in the deal. “We averted an economic crisis and an economic collapse.” Biden used the opportunity to itemize the achievements of his first term as he runs for reelection, including support for high-tech manufacturing, infrastructure investments and financial incentives for fighting climate change. He also highlighted ways he blunted Republican efforts to roll back his agenda and achieve deeper cuts. “We’re cutting spending and bringing deficits down at the same time,” Biden said. “We're protecting important priorities from Social Security to Medicare to Medicaid to veterans to our transformational investments in infrastructure and clean energy.” Even as he pledged to continue working with Republicans, Biden also drew contrasts with the opposing party, particularly when it comes to raising taxes on the wealthy, something the Democratic president has sought. It’s something he suggested may need to wait until a second term. “I’m going to be coming back,” he said. “With your help, I’m going to win.” Biden's remarks were the most detailed comments from the Democratic president on the compromise he and his staff negotiated. He largely remained quiet publicly during the high-stakes talks, a decision that frustrated some members of his party but was intended to give space for both sides to reach a deal and for lawmakers to vote it to his desk. Biden praised McCarthy and his negotiators for operating in good faith, and all congressional leaders for ensuring swift passage of the legislation. “They acted responsibly, and put the good of the country ahead of politics,” he said. Overall, the 99-page bill restricts spending for the next two years and changes some policies, including imposing new work requirements for older Americans receiving food aid and greenlighting an Appalachian natural gas pipeline that many Democrats oppose. Some environmental rules were modified to help streamline approvals for infrastructure and energy projects — a move long sought by moderates in Congress. The Congressional Budget Office estimates it could actually expand total eligibility for federal food assistance, with the elimination of work requirements for veterans, homeless people and young people leaving foster care. The legislation also bolsters funds for defense and veterans, cuts back some new money for the Internal Revenue Service and rejects Biden’s call to roll back Trump-era tax breaks on corporations and the wealthy to help cover the nation’s deficits. But the White House said the IRS' plans to step up enforcement of tax laws for high-income earners and corporations would continue. The agreement imposes an automatic overall 1% cut to spending programs if Congress fails to approve its annual spending bills — a measure designed to pressure lawmakers of both parties to reach consensus before the end of the fiscal year in September. In both chambers, more Democrats backed the legislation than Republicans, but both parties were critical to its passage. In the Senate the tally was 63-36 including 46 Democrats and independents and 17 Republicans in favor, 31 Republicans along with four Democrats and one independent who caucuses with the Democrats opposed. The vote in the House was 314-117. ___ AP Congressional Correspondent Lisa Mascaro contributed to this report. Read More Ukraine war’s heaviest fight rages in east - follow live Charity boss speaks out over ‘traumatic’ encounter with royal aide FBI offers to show GOP chairman document that purports to relate to Biden, his family Republicans schedule 1st presidential debate for Aug. 23, but there's no guarantee Trump will attend DeSantis wraps up 1st early states tour as candidate with more personal touch in South Carolina

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Roberto Mancini agreed a new five-year contract with Manchester City on this day in 2012. However, just 10 months later the City dream had soured and the title-winning manager wound up being sacked. The Italian manager took charge at the Etihad Stadium in 2009 and helped accelerate the club’s revolution under owner Sheikh Mansour. Mancini was rewarded with a long-term new deal after steering City to their first top-flight title in 68 years, when the Manchester side won the 2011-12 Premier League. Sergio Aguero’s last-ditch winner toppled QPR and saw City edge out rivals and neighbours Manchester United to claim the league crown. Mancini replaced Mark Hughes in December 2009, leading his side to the 2011 FA Cup before swiping the English championship a year later. “I am delighted to be able to give all of my efforts to Manchester City for a further five years,” said Mancini on completing his new extended deal. “The opportunity which exists to build on our recent success is enormous.” Sadly for Mancini, that enormous opportunity for City did not extend to him for much longer. City lost the 2013 FA Cup final 1-0 to Wigan, with the Latics suffering Premier League relegation to sit alongside their cup glory. That proved the final straw for City’s owners, after United had already sewn up the Premier League title with two games to play. Mancini was unseated by City on May 13, 2013 – just two days after that FA Cup final defeat. Assistant Brian Kidd took charge for the final two league games, with United eventually ending with an 11-point margin on second-placed City. Mancini would move on to further club management roles with Galatasaray, Inter Milan and Zenit St Petersburg before claiming Euro 2020 glory as Italy coach. Read More Charity boss speaks out over ‘traumatic’ encounter with royal aide Ukraine war’s heaviest fight rages in east - follow live Day four of third Ashes Test: England chasing 251 for victory at Headingley Wimbledon set for first Ukraine-Belarus clash of this year’s tournament Nasa Hataoka defies Pebble Beach conditions to seize US Women’s Open lead

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A recent investigation has found that some Ozempic and Wegovy patients suffered from severe gastroparesis, also known as stomach paralysis, after taking the medications. In a report from CNN published on 25 July, two patients reported that their “stomachs are paralysed” after taking type 2 diabetes drug Ozempic – a semaglutide injection known for its weight loss side effects. “I wish I never touched it. I wish I’d never heard of it in my life,” Joanie Knight, a 37-year-old from Louisiana, told CNN. “This medicine made my life hell. So much hell. It has cost me money. It cost me a lot of stress; it cost me days and nights and trips with my family. It’s cost me a lot, and it’s not worth it. The price is too high.” Emily Wright, a 38-year-old teacher from Toronto, said she vomits so frequently that she had to take a leave of absence from her job. “I’ve almost been off Ozempic for a year, but I’m still not back to my normal,” she said. According to CNN, both women have been diagnosed with severe gastroparesis, a disorder that slows or stops the movement of food from the stomach to the small intestine, per the Mayo Clinic. Wright has also been diagnosed with cyclic vomiting syndrome, which causes her to throw up multiple times a day. Meanwhile, one Wegovy user claimed she began experiencing stomach problems after her doctor prescribed her the weight loss drug – which works by mimicking a hormone called glucagon-like peptide 1 (GLP-1), regulating blood sugar levels and slowing down the rate at which food leaves the stomach to create the feeling of fullness. However, the medication caused her to vomit so much that she became dehydrated and needed to visit urgent care. Brenda Allen, from Texas, has since been managing her nausea and vomiting with a medication called Zofran and prescription probiotics. Now, the US Food and Drug Administration has said they’ve received reports of stomach paralysis among patients taking the medications. “The FDA has received reports of gastroparesis with semaglutide and liraglutide, some of which documented the adverse event as not recovered after discontinuation of the respective product at the time of the report,” the agency said in a statement to CNN. However, officials clarified that they were unable to determine whether taking Ozempic or Wegovy was the cause of stomach paralysis, or if it was caused by a different issue. “Gastroparesis can be a complication of diabetes that is related to long-standing or poorly controlled disease, further complicating the ability to determine what role the drugs played in the reported events,” they said. As for whether patients should be warned about taking the drugs, the FDA maintained that taking the medications, such as for treating diabetes or weight management, may still “outweigh the risks in some patients with gastroparesis or delayed gastric emptying”. In response to reports of stomach paralysis, Novo Nordisk – the manufacturer behind Ozempic and Wegovy – noted that these drugs have been extensively studied in the real world and in clinical trials. “Gastrointestinal (GI) events are well-known side effects of the GLP-1 class,” the company told CNN. “For semaglutide, the majority of GI side effects are mild to moderate in severity and of short duration. GLP-1’s are known to cause a delay in gastric emptying, as noted in the label of each of our GLP-1 RA medications. Symptoms of delayed gastric emptying, nausea and vomiting are listed as side effects.” Last week, the American Society of Anesthesiologists also issued a warning that those who take GLP-1 agonists should avoid the medications a week before surgery because they may increase “risk of regurgitation and aspiration of food” while under anesthesia and deep sedation. Ozempic, a once-weekly injection used for the treatment of type 2 diabetes, has skyrocketed in use after people were reportedly prescribed the FDA-approved diabetes medication as an “off-label” weight loss drug. However, because of its increasing popularity, it has led to national shortages of the diabetes treatment - leaving those who actually need Ozempic without it. Meanwhile, Wegovy and Mounjaro are popular once-weekly semaglutide injections specifically approved for the treatment of obesity and weight loss. There are many side effects of taking medications like Ozempic, Wegovy, and Mounjaro. According to the FDA, the most common side effects of taking Wegovy are nausea, diarrhea, vomiting, constipation, abdominal pain, headache, fatigue, indigestion, dizziness, and digestive disorders. The FDA has also warned about more serious complications that can occur from use of Wegovy or Mounjaro, such as the “potential risk of thyroid C-cell tumours,” pancreatitis, gallbladder problems, acute kidney injury, increased heart rate, and suicidal behaviour or thinking. Taking Ozempic can also lead to possible thyroid tumours, including cancer, pancreatitis, changes in vision, and kidney and gallbladder problems. The Independent has contacted Novo Nordisk and the FDA for comment. Read More Clinics told to stop prescribing medicines as weight loss drug hits diabetes supply Influencer addresses ‘dangers’ of complimenting people’s bodies after weight loss comments Ozempic under EU investigation over reports of suicidal thoughts Mindy Kaling shuts down weight loss question as ‘people take it so personally’ What are weight loss injections and what’s the controversy? Raven Symone says people shouldn’t use Ozempic for ‘glamazon purposes’

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