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1970-01-01 08:00

Erling Haaland at the double as Manchester City kick off new campaign in style
Erling Haaland’s brilliant brace helped Manchester City kick off their quest for an unprecedented fourth straight top-flight title with victory at promoted Burnley. Just two months on from winning the Champions League to become the second treble winners in English football history, Pep Guardiola’s men returned to competitive action with a bang at Turf Moor. Star man Haaland’s excellent first-half double and a close-range Rodri effort did the damage as City ran out 3-0 winners in the Premier League curtain raiser at Vincent Kompany’s Burnley. The 23-year-old frontman swept the visitors ahead 184 seconds into the new campaign and, with his side having lost skipper Kevin De Bruyne to injury, struck a stunning second off the underside of the bar. That display was not enough to avoid being chided by Guardiola as the teams made their way off at half-time, with the City boss pushing away a TV camera as he berated the striker. Rodri completed the scoring and Burnley substitute Anass Zaroury received a contentious late red card, with Community Shield runners-up City now turning their attention to Wednesday’s Super Cup clash against Sevilla. Both sets of players took the knee before kick-off and initial boos were drowned out by cheers at Turf Moor, where the hosts were behind after just three minutes and four seconds. De Bruyne took a short corner and, following a couple of passes, lifted a cross to the far post, where Rodri headed back across goal for Haaland to direct home impressively. It was a gut punch that De Bruyne tried to add to from distance, but the champions of the Championship stuck to Kompany’s principles. Burnley penalty appeals fell on deaf ears when Zeki Amdouni went down under pressure from Manuel Akanji before Luca Koleosho missed the target after fine, composed build-up. Amdouni wriggled free to get a shot on Ederson’s goal as Burnley continued to threaten City, whose youngster Rico Lewis was hit by an object thrown from the stands. The Lancashire club later confirmed the individual responsible had been identified and removed from the ground by police and now faces a banning order. Lewis was all right to continue, but De Bruyne soon had to leave the field. The skipper recently returned from a hamstring injury and, seemingly out of nothing, signalled to the bench that he had felt something, leading to Mateo Kovacic’s introduction. Burnley quickly attempted to capitalise. Amdouni was stopped by Rodri before the midfielder saw a pass cut out and Lyle Foster bent narrowly wide. But the hosts’ hopes of a comeback were short-lived as Haaland scored an incredible second in the 36th minute. Kyle Walker raced down the right and cut back to Julian Alvarez, who laid off for the Norwegian sharpshooter to sweep a first-time strike in off the underside of the bar. Haaland may have been on course for a hat-trick, but something had upset Guardiola, who pulled him back and scolded him before pushing the away a camera. The striker remained on as the visitors began the second half on top, with James Trafford – signed from City in the summer – tipping over a Rodri effort from distance and then saving a header from the Champions League final matchwinner. Alvarez fired off target after a show of strength by Haaland before City struck a third in the 75th minute as the match appeared to be petering out. Burnley failed to effectively clear a crossed free-kick and Rodri lashed home from five yards after Nathan Ake was blocked out. Alvarez saw a shot blocked before Josko Gvardiol came on for his City debut, with Haaland booed by the Burnley faithful when withdrawn as part of a triple City change. Guardiola made a point of getting up to give Haaland a warm greeting after their earlier exchange. Stewards reacted quickly as a fan attempted to get on the pitch towards the end of a night that had seen Burnley impress against mightily tough opposition. Things got worse for the promoted Clarets. Substitute Zaroury was sent off in stoppage time after his tackle on Walker was judged serious foul play after referee Craig Pawson watched the incident back on the VAR’s instruction. Read More Charity boss speaks out over ‘traumatic’ encounter with royal aide Ukraine war’s heaviest fight rages in east - follow live Anthony Joshua focused only on Robert Helenius amid Deontay Wilder speculation Harry Kane arrives in Germany to seal Bayern Munich move Ally Ewing out to emulate Brian Harman with Open win
2023-08-12 05:33

How did surgeons carry out Britain’s first womb transplant?
Surgeons worked all day and into the night to ensure Britain’s first womb transplant went smoothly. Its success is down to meticulous research, years of sharing knowledge between experts around the globe, and the hard work and dedication of doctors Professor Richard Smith, from Imperial College London, and Isabel Quiroga, from the Oxford Transplant Centre. Around 50 babies have been born worldwide as a result of womb transplants, which give women missing a functioning uterus a chance to have a baby. In the first UK case, the operation to remove the womb from the recipient’s 40-year-old sister lasted eight hours and 12 minutes, with surgeons leaving her ovaries behind to prevent pushing her into early menopause. One hour earlier, surgeons began operating on the 34-year-old recipient, preparing her body to receive the donated organ. This operation lasted nine hours and 20 minutes, with the surgical team experiencing some difficulties including a higher-than-expected blood loss of two litres. However, after just 10 days, the recipient was well enough to leave the hospital and has continued to have a good recovery. She is also having regular periods, which shows the womb is working well. Her sister was discharged five days after her donor operation and has also made a good recovery. Removing a womb is a similar operation to a radical hysterectomy, according to Prof Smith, who as well as being a gynaecological surgeon is the clinical lead at the charity Womb Transplant UK. He and Miss Quiroga led the team of more than 30 staff who worked on the transplant one Sunday in February. Prof Smith and Miss Quiroga removed the older sister’s womb, cervix and fallopian tubes, plus crucial blood vessels around the organ. The main vessels are the uterine arteries running into the womb, but the surgeons also aimed to collect some of the larger internal vessels that lead into the smaller branch of the womb. Prof Smith said surgeons doing these operations have to retrieve veins involved in the drainage of the womb. “One of the amazing things is that my surgical skill-mix as a cancer surgeon is to remove organs with a margin of normal tissue, while sealing the vessels as I go,” he said. “Transplant surgical skills are different – that is to remove a normal organ with the best number of non-sealed vessels as you can. “Isabel and I operate together with no ego – it just flows backwards and forwards across the table.” He added: “The day itself was truly humbling. We turned up at 7am at the Churchill transplant centre with the donor and the recipient families, then we went into a pre-op huddle. Those in the huddle included surgeons, nurses, anaesthetists and technicians. Prof Smith and Miss Quiroga worked to remove the womb, before the organ was prepared for transplantation by a “back table” team. “This was an organ which had a very, very unusual blood supply,” Prof Smith said. “In fact, it had a set of blood vessels which I’ve never seen in my entire career. They made my dissection a bit harder than it might have been, but we got there.” In the theatre next door, one hour before the retrieval of the womb was completed, surgeons began to operate on the donor’s younger sister to enable her to receive the womb. Prof Smith and Miss Quiroga switched from donor to recipient and Prof Smith removed the vestiges of the underdeveloped womb the recipient was born with. Meanwhile, the organ was packed and transported between the two theatres under sterile conditions to prevent contamination. A sterile bag with a cold perfusion solution contained the womb, which was then placed into a container with ice. During surgery, ligaments attached to the womb were attached to the recipient to help the womb stay in a relatively fixed place so it does not move around the pelvis. The most important part of the transplant operation was the joining of the very small vessels that give the blood supply to the womb. This was the most delicate and difficult part of the operation and was led by Miss Quiroga. Once all the vessels were connected, the donor’s vaginal cuff – around a 1cm part – was stitched into her sister’s vagina. If and when the recipient is able to complete her family, the womb will be removed six months later to prevent her from needing immunosuppressants for the rest of her life. Prof Smith said: “We know that the chance of failure at the point where the uterus goes in – if you look at the world literature – is 20 per cent to 25 per cent. And that failure is usually on the basis on sepsis and thrombosis. So technically, we are up to the job, but what happens thereafter can be scary. “Once you get to three or four days later, the chance of failure drops to probably less than 10 per cent. “Once you get to two weeks – and at the point where the woman has a period – the chance of her having a baby at that point is very high and the chance of failure has dropped to low. But those first two weeks – it’s very scary as a surgeon to watch and wait.” Biopsies to check the womb was functioning were read in London but then also confirmed by an expert team in the US at Baylor University Medical Centre in Dallas, where other womb transplants have been performed. Prof Smith said the procedure gives new hope to women born with devastating conditions. He said: “You’ve got girls, maybe 14, who have not had periods, they go to the GP and a scan shows there is no uterus. Absolute catastrophe. “Up until now, there’s been no solution for that, other than adoption or surrogacy... That’s not the case now. It’s really exciting.” On whether transgender women may also benefit from the operation, Prof Smith said that was still a long way off. He said the pelvic anatomy, vascular anatomy and shape of the pelvis are different, and there are microbiome issues to overcome. “My own sense is if there are transgender transplants that are going to take place, they are many years off. There are an awful lot of steps to go through. My suspicion is a minimum of 10 to 20 years.” Miss Quiroga said the living donor programme to date in the UK has focused on women with relatives who are willing to give their wombs. “It will come to a point where we will have friends or altruistic donors, like we have with many other transplants, but at the moment we’re only focused on people who have come forward with relatives,” she said. 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2023-08-23 07:00

Pakistan takes 3 wickets in opening session of 4th day against Sri Lanka in 1st test
Pakistan made early inroads in a bid to win the first cricket test against Sri Lanka as the visitors claimed three wickets on the morning of the fourth day
2023-07-19 15:14

'Quordle' today: Here are the answers and hints for June 4
If Quordle is a little too challenging today, you've come to the right place for
2023-06-04 05:01

CK Hutchison Slumps After Profit Drops, Warning on Risks
CK Hutchison Holdings Ltd. shares tumbled after the conglomerate founded by Hong Kong billionaire Li Ka-shing posted its
2023-08-04 10:04

Amazon Opens New Manhattan Offices at Former Lord & Taylor Site
Amazon.com Inc. has opened offices at the former Lord & Taylor building in midtown Manhattan, more than three
2023-09-12 23:58

Creator of ‘High on Life’ reveals why he made its gun talk back
The creator of ‘High on Life’ says he made the guns in his new shooter game talk back as he wanted to give players “lots of narrative surprises”.
1970-01-01 08:00

Australia coach defends keeping shock Kerr World Cup injury secret
Australia coach Tony Gustavsson has defended keeping Sam Kerr's Women's World Cup injury secret, saying he did so for tactical reasons and...
2023-07-21 11:14

Gabriel Jesus returns to Arsenal training ahead of Fulham clash
Gabriel Jesus has returned to Arsenal training ahead of the Premier League clash with Fulham.
2023-08-24 20:45

Thousands of discouraged migrants are stranded in Niger because of border closures following coup
Some 7,000 Africans who gave up on migrating to Europe have been stranded in Niger since the coup last month in which members of the presidential guard overthrew the West African nation’s democratically elected president
2023-08-23 11:02

Lufthansa Upbeat on Outlook as Travel Boom Extends to Full Year
Deutsche Lufthansa AG said it’s on track to meet its financial targets this year and in 2024 as
2023-11-02 14:00
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