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Premenstrual Dysphoric Disorder (PMDD) is a severe form of premenstrual syndrome (PMS), and is thought to affect more than one in 20 menstruating women. Actor and stand-up comedian Bella Humphries suffers from PMDD, and told the BBC: “My period sometimes makes me want to take my life.” According to the International Association for Premenstrual Disorders (IAPMD), 34% of the people who have been diagnosed with the condition have attempted suicide. Humphries, 29, continued: “It’s secrecy and silence that will kill people, not the disease or the disorder.” According to the IAPMD, it takes on average 12 years to be diagnosed with the condition. Here’s everything you need to know about it… What is PMDD? PMDD is a severe form of PMS, and is characterised by debilitating physical and emotional symptoms that occur during the time between ovulation and when the period is due to begin. This is known as the luteal phase and lasts around two weeks – although the length can vary from person to person. In June 2019, the World Health Organisation (WHO) added PMDD to the International Statistical Classification of Diseases and Related Health Problems, meaning it’s now recognised as a legitimate medical diagnosis. What are the symptoms? People with PMDD might experience a broad range of symptoms, and it’s different for everyone. “In PMDD, symptoms are extreme and can seriously impact quality of life, work and relationships. Many women report feeling suicidal,” said Dr Ghazala Aziz-Scott, a specialist in integrative women’s health and bioidentical hormone balancing for the Marion Gluck Clinic. “Symptoms can be cyclical and chronic – they include mood swings, anger, irritability, anger, anxiety, depression, anhedonia [the reduced ability to experience pleasure], fatigue, and brain fog. Physical symptoms include breast tenderness, headaches, bloating, food cravings, and insomnia.” Are there any treatments? Treatments can include “antidepressants, oral contraception and counselling”, said physician associate Simisola Ade. “A discussion with a doctor should be had to decide on what treatment is appropriate and how bad the PMDD symptoms are.” Aziz-Scott continued: “PMDD has a complex aetiology [causes] and it is vital to evaluate the root cause of the hormonal imbalance and if there are also any coexisting psychiatric conditions. “A healthy diet and good lifestyle can go a long way in supporting the body, B6 and magnesium supplementation are helpful and the use of natural progesterone in the second half of the cycle can be very beneficial.” What other things can people do to help? “Women who have PMDD need to be mindful and easy with themselves. Self-care is very important,” said Ade. “Also keeping a cycle diary is key, especially if you suspect you have PMDD, because some people aren’t aware that they have PMDD until they actually start tracking their symptoms and notice that they are cyclical. This can also help diagnosis and treatment be much quicker. “Talking to other people who have PMDD can be very beneficial too. There are international organisations that can help. Be open with your doctor and tailor treatments for yourself to ensure you put things in place when you are in that luteal phase. Getting to know your PMDD symptoms will help to make those symptoms more bearable.” Dr Adiele Hoffman, medical advisor at Flo Health agrees and said: “It’s very common to experience both emotional and physical discomfort in the days leading up to your period. However, these symptoms should not be so severe that they significantly impact your life, work, your family, or your other relationships. “But if they do, however, consistently affect your life, you should show these logs to a doctor. It can be very helpful for the doctor prescribing appropriate treatment. Most importantly, remember that no one should have to live with debilitating PMDD symptoms.” Read More Charity boss speaks out over ‘traumatic’ encounter with royal aide Ukraine war’s heaviest fight rages in east - follow live JW Anderson is teaming up with a major tennis star for new collection N-Dubz cement comeback with first new album in 13 years Irregular sleep patterns linked to harmful gut bacteria, study suggests

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In a nutshell: The grande dame of luxury London hotels, with a remarkable history and stellar service. Expect to be treated like royalty – for a price. The neighbourhood Only the heart of central London, my dear. Opened in 1889, London’s first luxury hotel is located on a bend of the River Thames on the Strand. Reached via Savoy Court – the only road in the UK where cars must drive on the right to enable guests to board and exit from the driver’s side of a car – this Grade II listed building benefits from being both perfectly situated for some of the city’s superlative attractions, while also transporting you to an altogether more magical place. It enjoys enviable access to some of London’s most popular cultural institutions, including the Royal Opera House, Somerset House, the National Gallery, the Courtauld Institute of Art and the National Portrait Gallery; and with a plum position in Theatreland, the Lyceum, Vaudeville, Adelphi, Duchess, Novello and Aldwych theatres are all just minutes away, in addition to the Savoy’s own namesake playhouse. The Victoria Embankment Gardens and Cleopatra’s Needle are situated at the rear of the hotel, while the South Bank and its attractions – including the Royal Festival Hall, National Theatre, Southbank Centre, Hayward Gallery and London Eye – are across the water. Read more on London travel: The best London hotels Where to shop and stay in London How to do winter in London right The vibe Opulent, old-school glamour without the stuffiness. Guests pass through the famous Art Deco front entrance before being ushered into the mahogany-panelled arrival hall, complete with marble columns, a black-and-white checkerboard marble floor, and plentiful vases of freshly cut floral displays. Luxury practically oozes from the walls, as does history; the roll-call of previous guests includes literary figures (Oscar Wilde, F Scott Fitzgerald, Mark Twain), former prime ministers (Winston Churchill), royalty (Queen Elizabeth II) and stars of stage and screen (Marlene Dietrich, Marilyn Monroe, Frank Sinatra, Elizabeth Taylor, Bob Dylan, The Beatles, Charlie Chaplin, Rihanna and Taylor Swift). The aesthetic is largely split between Art Deco and Edwardian, whether you’re sipping afternoon tea in the grand, light-filled Thames Foyer, complete with glass-domed atrium and winter garden gazebo, or quaffing fizz and celeb-spotting in the American Bar, London’s longest-surviving cocktail bar. Bed and bath The Savoy is home to 267 luxury guest rooms and suites decorated in a classic Edwardian or Art Deco style, ranging from Superior Queen Rooms, replete with marble bathrooms and bespoke Penhaligon’s toiletries, to the landmark Royal Suite (from £15,875 per night) designed by Gucci, whose founder worked at The Savoy as a luggage porter and lift boy as a young man. Many of the rooms feature outstanding panoramic views across the River Thames and South Bank that take in some of London’s most famous landmarks, including Big Ben, the London Eye and Oxo Tower. Suites include complimentary minibars, free-standing bathtubs and rainwater showers, Murano glass chandeliers, his and hers washbasins, chauffeur and butler services – and Boodles catalogues, in the event you fancy dropping six figures on some ice. Food and drink The American Bar is possibly one of the most famous hotel bars in the world, making a visit an essential element of any trip to London. Opened in 1893, its influence is global when it comes to the art of mixology, with celebrated bartenders creating the Hanky Panky, the White Lady, Prairie Oyster (as devoured by Sally Bowles in Cabaret) and the Moon Walk, Neil Armstrong’s bespoke concoction and first drink after his legendary trip to space. Famous patrons include Ernest Hemingway, Winston Churchill (a regular who kept his own bottle of whisky here), and F Scott Fitzgerald, while photographs of other acclaimed visitors can be found on the walls. Service is exquisite and discreet while the vibe is chic, with a pianist tickling the ivories. The newer Beaufort Bar, open Thursday to Saturday for champagne and cocktails, is the epitome of cocktail glamour, with black velvet furnishings, dim lighting and thousands of pounds worth of gold leaf on the walls. Dress up for this date night destination, which is also home to the original stage where George Gershwin performed the British premiere of “Rhapsody in Blue”. Competing with London’s culinary offerings is no mean feat, but the Savoy’s three restaurants – all of which are franchised to multi-Michelin-star awarded celebrity chef Gordon Ramsay – are more than fit for purpose. Specialising in shellfish and seafood, the River Restaurant is an absolute treat for pescatarians. The beef wellington – a house special – is also worth splashing out on, with juicy, tender meat encased in crisp and flaky pastry. Book a seat by the window and indulge in a seafood platter for the ultimate decadent dining experience. Described by Ramsay as the definition of “gourmet glamour”, the famous Savoy Grill’s sumptuous interiors – mirrored walls and plush velvets – have recently undergone a makeover to evoke the razzle-dazzle of the 1920s. Former regulars include the Queen Mother, Elizabeth Taylor, Noel Coward and Alfred Hitchcock; it’s also the place where Hollywood royalty, Vivien Leigh and Laurence Olivier, first set eyes on each other, with Leigh declaring then and there that she would marry Olivier. Hero dishes include lobster thermidor, Louet-Feisser oysters and duck a l’orange. Elsewhere, the more intimate Restaurant 1890 has just 26 covers and offers a modern French tasting menu that takes inspiration from influential former Savoy chef and culinary pioneer, Georges Auguste Escoffier. Located above the hotel entrance, try and bag a window seat for the ultimate people watching spot. Public areas Even the hotel’s lobby offers a sumptuous place to take the weight off your feet and soak up the atmosphere. Guests preferring to indulge further can head to the beauty and fitness centre. In addition to a range of treatments, such as massages and facials, resident and non-resident guests and members can take a dip in the 10m pool, equipped with a jet stream to swim against the current. The men’s and women’s changing areas also include a cosy sauna and steam room. A gym with weights and cardiovascular equipment is adjacent. Nuts and bolts Room count: 237 Freebies: Standard rooms provide complimentary tea, coffee, soft drinks and two beers, while suites extend this to include welcome drinks and butler service (one item of clothing for pressing per guest). Wifi: Free. Extra charges: None. Early check-in and late check-out are subject to availability, with charges determined on a case-by-case basis. Disability access: There are three accessible Deluxe King rooms, which feature wheel-in-shower and accessible-friendly amenities. All dining and bar venues are accessible; staff are available to assist guests with step-free routes. Pet policy: Well behaved pets up to 20lbs are welcome within the Savoy’s suites and rooms for a daily charge of £25. They are also welcome at the River Restaurant by Gordon Ramsay. Bottom line Best thing: The service is exceptional. That, and the sheer, unadulterated glamour, darling. Worst thing: The spa is on the petite side. Perfect for: A special occasion. Treat yourself – or someone else. It’s an unforgettable experience. Not right for: Large, noisy groups. Have some decorum! Instagram from: The dramatic red lift. London’s first electric lift was dubbed “an ascending room” by founder Richard D’Oyly Carte, with nervous passengers handed a glass of brandy to calm their nerves before entering. Its historic status, plus gold doors, red lacquer interior and leather bench for two make it an ideal place for posing. thesavoylondon.com Read more of our best luxury London hotel reviews Read More The best luxury hotels in London for a stylish city break The best spa hotels in London for pampering and indulgence Best boutique hotels in London 2022 How to do winter in London right Could a night at this ‘sleep retreat’ cure my insomnia? Loch Fyne Hotel and Spa, the ultimate secluded stay in the Scottish Highlands