Black Sea fleet commander Viktor Sokolov has appeared in a second video aired on Russian TV, days after Ukraine claimed he was killed in a missile strike on Sevastopol. A TV station run by Russia’s defence ministry showed an interview with the commander on Wednesday saying the fleet was performing successfully, although it was unclear from his comments whether the clip was filmed after Ukraine’s missile strike on 22 September. Ukraine’s special forces said on Monday that Mr Sokolov and 33 other officers were killed in the missile strike carried out on the Black Sea Fleet’s headquarters in Crimea. The new video comes after Russia’s defence ministry released another clip on Tuesday, appearing to show Mr Sokolov on a video conference call with Russian defence minister Sergei Shoigu. It also remains unclear when this video was recorded. Ukraine is now saying it is working to “clarify” earlier reports that he had died. Russia has not yet directly confirmed or denied the claims. Read More Viktor Sokolov seen for second time in newly emerged video as he claims Russia’s Black Sea Fleet ‘performing successfully’ New video of ‘dead’ Russian Black Sea fleet commander raises doubts over Ukraine’s claim Hillary Clinton mocks Putin over Nato expansion: ‘Too bad, Vladimir. You brought it on yourself’ Ukrainian forces ‘enjoy success’ near Bakhmut as Putin deploys reserves

Surgeons worked all day and into the night to ensure Britain’s first womb transplant went smoothly. Its success is down to meticulous research, years of sharing knowledge between experts around the globe, and the hard work and dedication of doctors Professor Richard Smith, from Imperial College London, and Isabel Quiroga, from the Oxford Transplant Centre. Around 50 babies have been born worldwide as a result of womb transplants, which give women missing a functioning uterus a chance to have a baby. In the first UK case, the operation to remove the womb from the recipient’s 40-year-old sister lasted eight hours and 12 minutes, with surgeons leaving her ovaries behind to prevent pushing her into early menopause. One hour earlier, surgeons began operating on the 34-year-old recipient, preparing her body to receive the donated organ. This operation lasted nine hours and 20 minutes, with the surgical team experiencing some difficulties including a higher-than-expected blood loss of two litres. However, after just 10 days, the recipient was well enough to leave the hospital and has continued to have a good recovery. She is also having regular periods, which shows the womb is working well. Her sister was discharged five days after her donor operation and has also made a good recovery. Removing a womb is a similar operation to a radical hysterectomy, according to Prof Smith, who as well as being a gynaecological surgeon is the clinical lead at the charity Womb Transplant UK. He and Miss Quiroga led the team of more than 30 staff who worked on the transplant one Sunday in February. Prof Smith and Miss Quiroga removed the older sister’s womb, cervix and fallopian tubes, plus crucial blood vessels around the organ. The main vessels are the uterine arteries running into the womb, but the surgeons also aimed to collect some of the larger internal vessels that lead into the smaller branch of the womb. Prof Smith said surgeons doing these operations have to retrieve veins involved in the drainage of the womb. “One of the amazing things is that my surgical skill-mix as a cancer surgeon is to remove organs with a margin of normal tissue, while sealing the vessels as I go,” he said. “Transplant surgical skills are different – that is to remove a normal organ with the best number of non-sealed vessels as you can. “Isabel and I operate together with no ego – it just flows backwards and forwards across the table.” He added: “The day itself was truly humbling. We turned up at 7am at the Churchill transplant centre with the donor and the recipient families, then we went into a pre-op huddle. Those in the huddle included surgeons, nurses, anaesthetists and technicians. Prof Smith and Miss Quiroga worked to remove the womb, before the organ was prepared for transplantation by a “back table” team. “This was an organ which had a very, very unusual blood supply,” Prof Smith said. “In fact, it had a set of blood vessels which I’ve never seen in my entire career. They made my dissection a bit harder than it might have been, but we got there.” In the theatre next door, one hour before the retrieval of the womb was completed, surgeons began to operate on the donor’s younger sister to enable her to receive the womb. Prof Smith and Miss Quiroga switched from donor to recipient and Prof Smith removed the vestiges of the underdeveloped womb the recipient was born with. Meanwhile, the organ was packed and transported between the two theatres under sterile conditions to prevent contamination. A sterile bag with a cold perfusion solution contained the womb, which was then placed into a container with ice. During surgery, ligaments attached to the womb were attached to the recipient to help the womb stay in a relatively fixed place so it does not move around the pelvis. The most important part of the transplant operation was the joining of the very small vessels that give the blood supply to the womb. This was the most delicate and difficult part of the operation and was led by Miss Quiroga. Once all the vessels were connected, the donor’s vaginal cuff – around a 1cm part – was stitched into her sister’s vagina. If and when the recipient is able to complete her family, the womb will be removed six months later to prevent her from needing immunosuppressants for the rest of her life. Prof Smith said: “We know that the chance of failure at the point where the uterus goes in – if you look at the world literature – is 20 per cent to 25 per cent. And that failure is usually on the basis on sepsis and thrombosis. So technically, we are up to the job, but what happens thereafter can be scary. “Once you get to three or four days later, the chance of failure drops to probably less than 10 per cent. “Once you get to two weeks – and at the point where the woman has a period – the chance of her having a baby at that point is very high and the chance of failure has dropped to low. But those first two weeks – it’s very scary as a surgeon to watch and wait.” Biopsies to check the womb was functioning were read in London but then also confirmed by an expert team in the US at Baylor University Medical Centre in Dallas, where other womb transplants have been performed. Prof Smith said the procedure gives new hope to women born with devastating conditions. He said: “You’ve got girls, maybe 14, who have not had periods, they go to the GP and a scan shows there is no uterus. Absolute catastrophe. “Up until now, there’s been no solution for that, other than adoption or surrogacy... That’s not the case now. It’s really exciting.” On whether transgender women may also benefit from the operation, Prof Smith said that was still a long way off. He said the pelvic anatomy, vascular anatomy and shape of the pelvis are different, and there are microbiome issues to overcome. “My own sense is if there are transgender transplants that are going to take place, they are many years off. There are an awful lot of steps to go through. My suspicion is a minimum of 10 to 20 years.” Miss Quiroga said the living donor programme to date in the UK has focused on women with relatives who are willing to give their wombs. “It will come to a point where we will have friends or altruistic donors, like we have with many other transplants, but at the moment we’re only focused on people who have come forward with relatives,” she said. 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CHESTERBROOK, Pa.--(BUSINESS WIRE)--Aug 1, 2023--

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Tottenham have stepped up their pursuit of new centre-backs for boss Ange Postecoglou amid the ongoing uncertainty over Harry Kane’s future. Kane remains of strong interest to Bayern Munich, who are expected to launch a third bid for the forward after officials from the German club reportedly met with Spurs chairman Daniel Levy in London on Monday. While speculation surrounding Kane continues to grow, Tottenham have accelerated their search for new defenders with talks advancing over the transfer of Wolfsburg’s Micky van de Ven, the PA news agency understands. Postecoglou gave the green light to Van de Ven’s signing soon after arriving in June and dialogue between the teams started last month. No final agreement over a fee – expected to be in the region of £30million – has been reached, but there is a growing confidence the Netherlands Under-21 international will make the move before Spurs’ Premier League opener at Brentford on August 13. After Van de Ven made 36 appearances for Wolfsburg in the 2022-23 campaign, and attracted interest from Liverpool, he made clear his desire to play in England during an interview with De Telegraaf in his homeland. “I have always dreamed of the Premier League because the biggest clubs play there and I also see that competition as the best in the world,” Van de Ven said in June. Tottenham also remain in talks with Bayer Leverkusen over the signature of centre-back Edmond Tapsoba, who alongside Van de Ven has been high on the club’s list of potential targets this summer. A move for both Bundesliga-based defenders has not been ruled out but Spurs are working on other transfers. Blackburn centre-back Ash Phillips is expected to complete his move to Tottenham this weekend. Spurs entered discussions with the Sky Bet Championship club last month for the England youth international, but negotiations stalled over a final transfer fee. After Friday a £2million release clause for Phillips will become active, which will allow Tottenham to complete the signing of the 18-year-old. Phillips’ arrival will not impact on Postecoglou’s desire to boost his senior options in defence, with the centre-back viewed as a player for the future. Tottenham have also opened talks with Rosario Central over 19-year-old forward Alejo Veliz. Veliz impressed at the Under-20 World Cup this summer, scoring three goals for Argentina. Discussions are at an early stage but Spurs are eager to make a number of signings during a busy final month of the summer transfer window. Read More Charity boss speaks out over ‘traumatic’ encounter with royal aide Ukraine war’s heaviest fight rages in east - follow live Great Britain’s team pursuit world title defence ends with crash in qualifying Ally McCoist: Michael Beale and Brendan Rodgers need to put friendship on hold Eddie Nketiah ready to step up again after Gabriel Jesus’ injury

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