Eleven million people watched the U.S. Republican presidential candidates' prime-time debate Wednesday on Fox News, according to Nielsen,

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New figures show a dramatic rise in the number of women deciding to freeze their eggs. A report from the Human Fertilisation and Embryology Authority (HEFA) found that egg and embryo freezing are now the fastest growing fertility treatments in the UK. Egg freezing and storage saw a 64% rise between 2019 and 2021 – increasing from 2,576 cycles to 4,215 completed. What is egg freezing? It’s where a woman’s eggs are extracted and frozen immediately for fertilisation at a later date. Gynaecologist Dr Larisa Corda said it’s a “means of helping preserve fertility for the future”. Freezing the eggs at the point of extraction means they avoid the decline in quality that’s associated with ageing. “It essentially means that a woman becomes her own egg donor later in life, when she decides she wishes to have children,” she said. What’s the process? “It involves the same sort of procedure as the first part of IVF, where a woman takes injections to stimulate her ovaries, to encourage follicles to grow and lead to egg maturation over several days. “After that, the eggs are collected via a simple surgical technique using a needle placed into the vagina and then into the ovaries, to aspirate the eggs which are there,” Corda said. The daily injections (usually for eight to 11 days) involved in the first part of the process is to encourage the ovaries to produce more eggs. “They may be uncomfortable and lead to side-effects like bloating, abdominal pain, nausea, headaches and other hormonal symptoms, such as breast soreness and changes to your mood,” she added. Women are usually put to sleep for the egg retrieval, during which, a long needle is inserted into the vagina to reach the ovaries and remove the fluid in each follicle that contains an egg. “This is all done under direct ultrasound guidance and normally takes around 30 minutes. You will not feel anything during the procedure, but afterwards, you may have some cramps and a bit of bleeding, which all normally settles down within 24-48 hours.” How many eggs are usually frozen each time? It really depends how many are produced by the patient at the time. Corda said the number of eggs doesn’t give a good indication on the quality though – which is only revealed after the eggs are fertilised to create embryos further down the line, when the woman or couple want to try to have a baby. “Because of this reason, women are advised to freeze between 10-15 eggs, to give themselves a good, reasonable chance. This may involve doing several rounds of egg freezing, but there’s no guarantee of success,” she said. The aim varies depending on the clinic though, and the “numbers needed when older become much more unpredictable, and it also becomes much harder to get a good number of eggs too”. What’s the success rate? The success rates are dependant on age and the quality of the eggs. “Not surprisingly, the highest live birth rates from previously frozen eggs are shown to come from women who undergo the procedure before they are 30,” she noted. “However, the average age at which women freeze their eggs is around 37, with many women closer to 40 by the time they consider doing this.” She said it’s generally agreed that the best time is before age 36, when most women’s eggs are still a sufficient quality and you’re more likely to use them in the future (as opposed to someone age 25 and more likely to fall pregnant without medical assistance). It’s important to know that some eggs won’t actually make it, even if they were fine at the freezing stage. Dr Suvir Venkataraman, from the Harley Street Fertility Clinic, added: “For a good prognosis patient, i.e. under 35 with no known fertility issues, roughly 90% of eggs survive freezing and thawing by vitrification. “Approximately 70% of those will be fertilised by good sperm to create embryos. Approximately 50% of those embryos will develop well. And there’s approximately 30% chance of live birth per embryo transferred.” How much does it cost? The Human Fertilisation and Embryology Authority (HFEA) estimate the average cost of freezing eggs is £7,000-£8,000 – including medication, storage costs and the later process of thawing and transferring to the womb. But it varies from clinic to clinic. What else should you consider? Arm yourself with all the facts on the costs, and understand it’s not a guaranteed insurance policy for getting pregnant in the future. “It’s important to see a fertility specialist to get assessed before considering egg freezing, as the decline in egg number and quality can start much earlier for some women,” Corda said. “If you’re not sure what clinic to go to, the HFEA website has lots of great and useful information to help you to decide and check out their credentials. “Egg freezing does not offer any guarantees, but for a lot of women, it is the best possible chance of having their own biological children later in life.” Read More Charity boss speaks out over ‘traumatic’ encounter with royal aide Ukraine war’s heaviest fight rages in east - follow live How can you save money on your wedding food? Regular napping could be good for brain health, research suggests Dramatic rise in the number of women freezing their eggs

The Middle East plays host to its second straight U.N. climate conference over the next two weeks, with countries hoping to agree on new ways to keep the planet from catastrophic heating by the end of the century

England advanced to the World Cup semi-finals with a 2-1 comeback victory over Colombia, and will play tournament co-hosts Australia in Sydney on Wednesday night. Here, the PA news agency breaks down some of the key questions ahead of The Lionesses’ meeting with the Matildas. How did they get here? England secured victories over Haiti, Denmark and China to reach the knockouts, scoring multiple times in a group stage contest just once with a 6-1 triumph over China. The Lionesses next faced Nigeria in the last-16, who held them to 120 goalless minutes before England booked their quarter-final place with a 4-2 win on penalties. England conceded for just the second time this tournament late in the first half of the quarter-final clash with Colombia at Sydney’s sold-out Stadium Australia, but they were level by the break thanks to Lauren Hemp’s alert stoppage-time effort and Alessia Russo completed the comeback after the break. What is England’s history in World Cup semi-finals? The Lionesses’ first appearance in the final four, eight years ago in Canada, ended in heartbreak. England were up against defending champions Japan, who took the lead through captain Aya Miyama’s 32nd-minute opener but saw it cancelled out by Fara Williams after just seven minutes. The 1-1 draw looked destined for extra time until Laura Bassett directed a clearance into her own net in the first minute of second-half stoppage time and broke down in tears while Japan celebrated their last-gasp luck. England ultimately beat Germany 1-0 through Williams’ extra-time penalty in the third-place playoff – still their best-ever finish in a global showpiece. Four years later, the Lionesses beat Norway 3-0 in the last eight in France to set up a semi-final with the United States, who beat England 2-1 en route to defending their 2015 title. The Lionesses finished fourth overall after losing 2-1 to Sweden in the play-off. How good are Australia? The Matildas are 10th in FIFA’s global rankings, six places below England, but can boast they are the only team to have beaten the Lionesses since boss Sarina Wiegman took the helm in September 2021. That victory came in April, when Sam Kerr and Charlotte Grant both scored at Brentford to snap Wiegman’s 30-game unbeaten streak as England manager with a 2-0 victory. Captain Kerr was unavailable for her side’s first two World Cup matches with a calf injury, yet the talismanic Chelsea striker’s absence might have actually benefitted the Matildas in the long run as others were asked to step up, with Hayley Raso and Mary Fowler among those who emphatically answered the call for the co-hosts. Kerr returned as a late second-half substitute in her side’s 2-0 victory over Denmark in the last 16, five days before the Matildas sealed their first-ever trip to a semi-final by beating France in the longest penalty shootout in Women’s World Cup history. Long gone are the days Australians feared their side could be knocked out at the group stage. Momentum – and an increasingly enraptured nation – are firmly on their side. What is the biggest challenge facing England? England will have to cope without star forward Lauren James as she serves the final game of a two-match suspension for stepping on the back of Nigeria’s Michelle Alozie. She was replaced by Ella Toone against Colombia, who after the match said: “She’s been amazing for us, but I’ve got to believe in myself and I’ve got to have that confidence going onto the pitch. I don’t let anything get me down, I don’t put that pressure on myself and I know my team-mates don’t either.” How will England cope with the crowd? Stadium Australia boasts more than 75,000 seats, most of which will be occupied by the home support. That does not faze England captain Millie Bright, who said: “For me, no matter who the fans are, you’re actually quite proud of it as well, we want that in a World Cup, we want it to be people turning on the TV and saying ‘god, look at the crowd, it’s incredible’. “As a player you feel that and you use it to your advantage as well, it’s not a disadvantage that there might be a lot of Australia fans there. “ Read More Charity boss speaks out over ‘traumatic’ encounter with royal aide Ukraine war’s heaviest fight rages in east - follow live Sean Dyche hopes Everton are close to solving their goalscoring problems On this day in 2016: Mo Farah retains Olympic 10,000m title in Rio Anthony Joshua confident fight with Deontay Wilder will happen ‘soon’

TOKYO--(BUSINESS WIRE)--Nov 23, 2023--

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