Normally when a drug fails to show a clear effect in a final-stage trial, the company developing it

Zoom Video Communications Inc., a one-time darling of the work-from-home era, is calling workers back to the office.

Mauricio Pochettino’s start to life as Chelsea manager has been somewhat of a mixed bag with the Blues lying 10th after 12 games of the Premier League season. A recent 4-1 win at title-chasing Tottenham and draws against Arsenal and Manchester City suggest the Blues are beginning to turn a corner after taking only five points from their first six league games. Here, the PA news agency breaks down Chelsea’s season so far under Pochettino. A poor start Chelsea’s unbeaten pre-season form did not translate to the Premier League where they struggled to pick up points in the early stages. An opening day 1-1 draw to Liverpool was followed by a 3-1 defeat at West Ham before the Blues went winless in their next three against Nottingham Forest, Bournemouth and Aston Villa. The 1-0 defeat at home to Villa saw Pochettino call for his players to “grow up” after the Blues’ stuttering start saw the pressure mount on their Argentinian manager. A young team All of Chelsea’s 12 summer signings are aged 25 and under as chairman Todd Boehly looked to recruit youth as a solution to last season’s poor performances, which led to a dismal 12th-place finish in the Premier League. The upheaval to the squad in the summer led to the Blues’ early teething problems as Pochettino juggled formations and XIs in a bid to find his preferred personnel. Is Cole Palmer Chelsea’s main man? Cole Palmer has been a mainstay in Chelsea’s XI since his September transfer from Manchester City. The winger, who has also featured as an attacking midfielder, cost a reported £42.5 million and has scored four times from the spot against Burnley, Arsenal Spurs and a last-minute equaliser in Sunday’s 4-4 draw against his old club City. Palmer’s creativity has helped Nicolas Jackson unlock his goalscoring touch, with the Senegal striker netting four times in his last two appearances. Turning the corner? The west London club have picked up six points in four games against the so-called ‘big six’, which is an improvement on the four points they managed across the whole of last season against their rivals. Although Chelsea have had success against high-pressing opposition, they still need to find solutions to combat low blocks after their recent 2-0 defeat to Brentford at Stamford Bridge. Read More The issues facing injury-hit Newcastle heading into testing end to year Ben Davies keen to prove doubters wrong as Wales target another major tournament Britain’s Katie Boulter eager to build on her successful season in 2024

AUSTIN, Texas--(BUSINESS WIRE)--Jun 28, 2023--

Vanna White was paid far less than Pat Sajak and received no pay increment for her role for 18 years

The former Navy SEAL who claims to have shot and killed Osama bin Laden has been arrested in Texas. Robert O’Neill, 47, was booked into jail in Frisco on Wednesday and released later that day on a $3,500 bond, reported The Dallas Morning News. He was charged with a Class A misdemeanour of assault causing bodily injury and a Class C misdemeanour charge of public intoxication. Mr O’Neill was a member of SEAL Team 6 during the famed 2011 mission and subsequently claimed that he had fired the shots which killed the al Qaeda leader and September 11 mastermind at his Pakistan compound. Mr O’Neill had been in the Dallas area to record a podcast at a cigar lounge, according to The New York Post. It is not Mr O’Neill’s first run-in with law enforcement. In 2016, he was arrested in Montana on suspicion of driving under the influence after police said they found him asleep in the driver’s seat of a vehicle with the engine still running, reported The Montana Standard. He blamed a prescription sleeping pill that he told officials he took to deal with insomnia and prosecutors dropped the charges. He was instead charged with negligent endangerment and the prosecution was deferred while he underwent treatment. Mr O’Neill, who is from Montana, was banned from flying on Delta Air Lines after he posted a photo of himself without a mask, when it was still required because of Covid-19. He first made his claim that he was the person who killed Osama bin Laden in a 2014 interview with The Washington Post. The US government has never confirmed nor denied his claim, and different accounts of the operation have clouded who actually pulled the trigger. Some in the special operations community have criticised Mr O’Neill for breaking the code of silence associated with Naval Special Warfare. The official version of events will likely not be de-classified for decades. Read More Plea negotiations could mean no 9/11 defendants face the death penalty, the US tells families Afghanistan is moving into a darker future – and we are letting it happen A top lawyer’s son, a FBI raid and ‘weapons of mass destruction’: How a Philly teen allegedly turned ‘aspiring terrorist’

Pete Davidson and his girlfriend Chase Sui Wonders, bought a Cavapoo puppy from a breeder last month from Citipups in Manhattan

The production designers who worked on Barbie have revealed the biggest challenges about bringing Barbieland to life - after nine whole months of conversations with director, Greta Gerwig, on how it should look. Sarah Greenwood and Katie Spencer were responsible for the incredible aesthetics of the dream houses. “What do you put in a house with no walls? And through these walls, you see the house next door", Spencer says. “There’s nowhere to hide. It has to look utterly gorgeous but relatable. And then there’s the scale of things… the lower the house, the shallower the rooms. You couldn’t put an awful lot in them.” Sign up to our new free Indy100 weekly newsletter

American teenager Coco Gauff qualified for the third round of the US Open on Wednesday after beating 16-year-old Russian...

Everton has been handed the biggest sporting sanction in the Premier League’s 31-year history for breaching the competition’s financial rules with the deduction of 10 points dropping the team into next-to-last place in the standings

To play Urzikstan early in Call of Duty: Modern Warfare III, fans must play Zombies mode to experience the new Warzone map before it launches.

The president of Cyprus says he personally asked an unnamed “third country” to send an experienced team of financial crime experts to help the east Mediterranean island nation with investigations into old and new allegations that Cypriot financial service providers helped Russian oligarchs skirt international sanctions