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Bunge Ltd.’s boss says the agricultural trader’s deal to buy Glencore-backed Viterra won’t lead to a cull of

Sharon Osbourne explained that she started using diabetes-turned-weight-loss medication in December last year but has been 'off it for a while now'

Scientists have developed eye scans that use artificial intelligence to detect markers of Parkinson’s disease seven years before symptoms appear, making it the first time the condition can be detected several years before diagnosis. Parkinson disease’s is a deteriorating neurological condition characterised by a reduction of dopamine. The research, published on Tuesday in the journal Neurology, used two large sets of health data – the AlzEye dataset and the UK Biobank database – to identify these subtle markers, even though Parkinson’s disease has a relatively low prevalence among this population. The AlzEye dataset was formed from the world’s largest database of retinal images and associated clinical data. Post-mortem examination of Parkinson’s patients has found differences in the retina’s inner nuclear layer (INL). Previous studies have shown eye-scan data can reveal signs of other deterioration of neurological conditions like Alzheimer’s, multiple sclerosis and schizophrenia. The studies are part of an emerging field of research called “oculomics”. Eye scan data has also been shown to reveal people’s propensity to high blood pressure, heart disease, stroke and diabetes. Doctors have historically conducted physical eye tests, believing the organ can act as a “window” to the rest of the body, and provide direct insight into many aspects of human health. With high-resolution images of the retina now a routine part of eye care, scientists said the data from these scans can be put to better analysis to gain better insights on patient health. In particular, a type of 3D scan known as optical coherence tomography (OCT) is widely used in eye clinics and by high-street opticians. These scans can produce a cross-section of the retina – the screen of nerves at the back of the eye – in incredible detail down to a thousandth of a millimetre. Images of the retina can be extremely useful for monitoring eye health. But researchers said their value can become much more as a retinal scan is the only non-intrusive way to view layers of cells below the skin’s surface. They found in the new study that a reduced thickness of these cell layers was associated with an increased risk of developing Parkinson’s disease. Scientists have also started using powerful computers and AI technology to accurately analyse large numbers of OCTs and other eye images, in a fraction of the time it would take a human. “While we are not yet ready to predict whether an individual will develop Parkinson’s, we hope that this method could soon become a pre-screening tool for people at risk of disease,” study co-author Siegfried Wagner from the University College London said. “Finding signs of a number of diseases before symptoms emerge means that, in the future, people could have the time to make lifestyle changes to prevent some conditions arising, and clinicians could delay the onset and impact of life-changing neurodegenerative disorders,” Dr Wagner said. Researchers said the OCT method used in the study is also non-invasive of lower cost, more scalable and quicker than brain scans for this purpose. Read More Study could lead to injections that replicate brain benefits of exercise Dementia breakthrough as drug treatment comes one step closer Parkinson’s therapy could be used to tackle alcohol abuse Justin Trudeau slams Facebook for blocking news stories about wildfires Microsoft makes big changes to takeover of Activision Blizzard Meta could finally launch Threads feature everyone is waiting for

DAYTON, Ohio--(BUSINESS WIRE)--Oct 5, 2023--

With its white marble foyer and lavish chandeliers, the 12-storey tower could be mistaken for one of Hong Kong’s newest hotels, but it offers a longer stay: a final resting place for thousands in...

Imran Khan said Pakistan’s military establishment wanted to stop his opposition party from winning the next election, paving

Officials say at least 16 people are dead after a man opened fire at a restaurant and a bowling alley in Lewiston, Maine

IRVINE, Calif.--(BUSINESS WIRE)--Jul 18, 2023--

STAMFORD, Conn.--(BUSINESS WIRE)--Nov 30, 2023--

Goals from Said Benrahma and Michail Antonio kept West Ham’s dreams of a first trophy in 43 years alive after a 2-1 victory in the first leg of the Europa Conference League semi-final against AZ Alkmaar. The Hammers were big favourites to beat the Dutch dark horses, but were put on the back foot at a sold-out London Stadium when goalkeeper Alphonse Areola gifted AZ the lead before half-time. But another goalkeeping error from Australia international Mathew Ryan gave West Ham a penalty which Benrahma converted. Antonio then prodded home from a corner after a goalmouth scramble to give the Hammers a crucial lead going into next Thursday’s second leg in the Netherlands. There was a sense of optimism before kick-off with West Ham almost safe from relegation and captain Declan Rice confidently predicted ‘the good times are back on their way’ in his programme notes, even though it remains unlikely he will be here to enjoy them for much longer. Still, a European final in Prague on June 7, against Fiorentina or Basel, would be a fitting way for the England midfielder to sign off before a big-money summer move. But AZ, a progressive club based around the moneyball model also used by Brentford, are a slick, attacking young side who had beaten Lazio and Anderlecht to reach the last four. They were watched from the directors’ box by Billy Beane, the real-life inspiration for Brad Pitt’s character in the baseball movie Moneyball, who owns a stake in them. Ominously, AZ goalkeeper Ryan was unbeaten in his five previous matches against West Ham during his spell at Brighton, and he set about trying to maintain that record when he got down well to tip Benrahma’s curler behind. West Ham were given a painful lesson in last season’s Europa League semi-final, conceding in the first minute of the first leg and losing Aaron Cresswell to a red card in the second as they crashed out to Eintracht Frankfurt. They got an early warning when former Southampton midfielder Jordy Clasie fizzed a low shot just past the post. And history repeated itself when West Ham allowed AZ to take a shock lead five minutes before half-time, Areola letting Tijjani Reijnders’ shot in at his near post. It was not a gaffe on the scale of the one West Ham benefitted from in their win over Manchester United on Sunday, when David De Gea let Benrahma’s tame shot roll in, but it was still not a good look for the Hammers’ cup keeper. West Ham protested that there had been a foul on Lucas Paqueta in the build-up – Turkish referee Halil Umut Meler even put the whistle to his lips before opting to play on – but the goal stood. However, the hosts were thrown a lifeline in the 67th minute when Ryan missed his punch at a corner and caught Jarrod Bowen square in the face. Meler, who had infuriated the home crowd all match, pointed to the penalty spot and Benrahma stepped up to bury a perfect spot-kick just inside the post. Eight minutes later West Ham went ahead, Antonio stabbing home the rebound after Nayef Aguerd’s header was cleared off the line to give them a slim advantage and, if they improve next week, every chance of moving a step closer to a first European trophy since 1965. Read More Charity boss speaks out over ‘traumatic’ encounter with royal aide Ukraine war’s heaviest fight rages in east - follow live Ronnie O’Sullivan shows how versatile his book is – Thursday’s sporting social Counties cast rivalry aside and honour the life of Matt Dunn’s daughter Overseas territories should have representation in Parliament, ministers told

Appeals court judges in Amsterdam say the Dutch government can order Schiphol Airport, one of Europe’s busiest aviation hubs, to reduce the number of flights from 500,000 per year to 460,000