Scientists have developed eye scans that use artificial intelligence to detect markers of Parkinson’s disease seven years before symptoms appear, making it the first time the condition can be detected several years before diagnosis. Parkinson disease’s is a deteriorating neurological condition characterised by a reduction of dopamine. The research, published on Tuesday in the journal Neurology, used two large sets of health data – the AlzEye dataset and the UK Biobank database – to identify these subtle markers, even though Parkinson’s disease has a relatively low prevalence among this population. The AlzEye dataset was formed from the world’s largest database of retinal images and associated clinical data. Post-mortem examination of Parkinson’s patients has found differences in the retina’s inner nuclear layer (INL). Previous studies have shown eye-scan data can reveal signs of other deterioration of neurological conditions like Alzheimer’s, multiple sclerosis and schizophrenia. The studies are part of an emerging field of research called “oculomics”. Eye scan data has also been shown to reveal people’s propensity to high blood pressure, heart disease, stroke and diabetes. Doctors have historically conducted physical eye tests, believing the organ can act as a “window” to the rest of the body, and provide direct insight into many aspects of human health. With high-resolution images of the retina now a routine part of eye care, scientists said the data from these scans can be put to better analysis to gain better insights on patient health. In particular, a type of 3D scan known as optical coherence tomography (OCT) is widely used in eye clinics and by high-street opticians. These scans can produce a cross-section of the retina – the screen of nerves at the back of the eye – in incredible detail down to a thousandth of a millimetre. Images of the retina can be extremely useful for monitoring eye health. But researchers said their value can become much more as a retinal scan is the only non-intrusive way to view layers of cells below the skin’s surface. They found in the new study that a reduced thickness of these cell layers was associated with an increased risk of developing Parkinson’s disease. Scientists have also started using powerful computers and AI technology to accurately analyse large numbers of OCTs and other eye images, in a fraction of the time it would take a human. “While we are not yet ready to predict whether an individual will develop Parkinson’s, we hope that this method could soon become a pre-screening tool for people at risk of disease,” study co-author Siegfried Wagner from the University College London said. “Finding signs of a number of diseases before symptoms emerge means that, in the future, people could have the time to make lifestyle changes to prevent some conditions arising, and clinicians could delay the onset and impact of life-changing neurodegenerative disorders,” Dr Wagner said. Researchers said the OCT method used in the study is also non-invasive of lower cost, more scalable and quicker than brain scans for this purpose. Read More Study could lead to injections that replicate brain benefits of exercise Dementia breakthrough as drug treatment comes one step closer Parkinson’s therapy could be used to tackle alcohol abuse Justin Trudeau slams Facebook for blocking news stories about wildfires Microsoft makes big changes to takeover of Activision Blizzard Meta could finally launch Threads feature everyone is waiting for

A group of influencers have come under fire after posting glowing videos from their paid trip to a factory owned by controversial fast fashion retailer Shein in Guangzhou, China. Shein, which has been previously accused of labour abuse and admitted to breaching rules around working hours, brought the group of six fashion influencers from the US to tour its “Innovation Factory”. Influencer and model Dani Carbonari was one of the influencers who went on the trip and posted a video tour on her social media last week. After facing criticism from her followers – of which she was more than 481k on Instagram and nearly 300k on TikTok – Carbonari appears to have deleted the post. In her original post, she wrote in her caption that the trip to Shein’s factory gave her the opportunity to see with her “own two eyes what the entire process of Shein clothing looks like from beginning to end”. “I feel more confident than ever with my partnership with Shein. There are so many companies not taking half the initiative Shein is. They are aware of every single rumour and instead of staying quiet they are fighting with all of their power to not only show us the truth but continue to improve and be the best they can possibly be,” the “confidence activist” continued. The video showed a brightly lit factory, with staff working in clean, dust-free conditions and automated bots that assisted with processing and packaging orders. The other influencers, Destene Sudduth, Aujene, Fernanda Stephany Campuzano, Kenya Freeman, and Marina Saavedra, also shared similarly glowing Instagram posts about their visit. Viewers have pointed out that the influencers appeared to use a “script” for their posts, as they involved similar language. In her post, Saavedra said: “Like many others, I’ve heard a lot of misinformation”, while Carbonari wrote: “You have to remember our country is filled with so much prejudice – we want to believe we’re the best and no one else can be better.” @shein_us Get a glimpse of the process of how your purchases are packaged directly from our facility and delivered to your doorstep. Watch as our partners discover the cutting-edge tech that streamlines our operations and receive a hands-on experience in packaging. Stay tuned to the #SHEIN101 series to learn more of what goes on behind the scenes at #SHEIN #SHEINOnTheRoad ♬ original sound - SHEINUS But viewers have pointed out that the influencers’ comments about the Shein factory they saw – one of 6,000 factories that the online retailer has, according to Time magazine – do not address the allegations that have been levelled over Shein’s labour and environmental impact. Channel 4 launched an investigation last year that involved an undercover worker filming inside two Shein factories in Guangzhou and found that workers receive a base salary of 4k yuan per month (approximately £434) to produce 500 pieces of clothing per day. The investigation also found that workers in both factories were working up to 18-hour days regularly and were only given one day off a month. Later, Shein said that after conducting an independent investigation, it found that employees indeed working longer hours than the local laws allowed. Shein found that staff at one factory were working up to 13-and-a-half hour days with two to three days off a month, while those at the second site worked up to 12-and-a-half hour days with no fixed structure for days off. It said that “while these are significantly less than claimed in the documentary, they are still higher than local regulations permit”. At the time, Shein vowed to invest US$15m (£11.8m) to improve standards at its supplier factories. On Twitter, one person wrote: “Shein is sending the influencer girlies to China to some (PR) ‘innovation’ factory where it looks pristine and super clean and the workers are having fun while sewing and the company saying they pay a ‘competitive’ wage lol.” Another said: “The funniest part of the Shein debacle to me is the influencers acting like they went undercover to investigate. You were invited, of course, it’s PR.” A third added: “Them Shein influencers getting cooked and Shein ain’t [sic] defending them. Meanwhile the girls are doing their best to explain to us why Shein ain’t too bad. It’s sad.” The Independent has contacted Shein, Carbonari, Sudduth, Aujene, Campunazo, Freeman and Saavedra for comment. Read More Give Greenpeace a chance: Art and activism join forces for Glastonbury’s campaign for the future Harry and Meghan’s ‘lack of productivity’ left Spotify and Netflix bosses ‘underwhelmed’, report says A woman stopped cleaning after her husband accused her of doing ‘nothing’. Then she filmed the results Princess Diana’s ‘black sheep’ jumper predicted to sell at auction for up to £70,000 The best onstage fashion at Glastonbury Glastonbury 2023: All the best fashion at the biggest UK festival of the year

Barcelona have confirmed that Ronald Araujo has suffered a hamstring injury.

Starting from nothing and building a successful civilization is one of the most satisfying things. That's why games like Minecraft and Sid Meier's Civilizations are always fun.

MARRAKECH The European Central Bank should aim to engineer a "soft landing" for the euro zone's economy as

The NBA All-Star Game returns to Indianapolis for the first time since 1985, with the same format that has been used since 2020, including the player draft and Elam Ending.

The House on Thursday passed a Federal Aviation Administration reauthorization bill to renew funding for the agency for the next five years.

Air New Zealand said on Tuesday that Pratt & Whitney maintenance of its Geared Turbofan jet engine fleet

Arizona, California and Nevada on Monday proposed a deal to significantly cut their water use from the drought-stricken Colorado River over the next three years

A lineup of post-pandemic music concerts, from Coldplay to Blackpink, has driven more Indonesians to turn to fintech

Strong demand from consumers willing to pay up for bookings pushed Royal Caribbean Cruises Ltd. shares to the

The head of the union that represents track maintenance workers says Union Pacific is jeopardizing safety by delaying nearly 1,200 planned projects until next year and laying off more than 1,000 workers