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Real Madrid host the first leg of their Champions League semi-final against Manchester City as they continue to chase another European trophy. Carlo Ancelotti’s side have already progressed beyond two English clubs in the knockout rounds, showing all of their competition-winning acumen in beating Liverpool and Chelsea. But the Spanish capital club know they will face a significantly stronger side with the Premier League leaders in town. Manchester City are in outstanding form and desperately covet the continental crown that has so far eluded them. Here’s everything you need to know. When is Real Madrid vs Manchester City? Real Madrid vs Manchester City is due to kick off at 8pm BST on Tuesday 9 May at the Bernabeu in Madrid. How can I watch it? Viewers in the United Kingdom can watch the first leg live on BT Sport 1, with coverage on the channel from 7pm BST. Subscribers can stream the game via the BT Sport app or online player. Team news Real Madrid are dealing with a couple of defensive issues, with Eder Militao suspended for this fixture and Ferland Mendy still battling a calf injury. Luka Modric should, however, be fit to start after overcoming his hamstring issue to feature in the Copa del Rey win on Sunday. Kevin De Bruyne returned to the starting Manchester City side against Leeds in a timely boost for Pep Guardiola, though Nathan Ake’s second half substitution during that encounter is cause for concern. The Dutch defender’s hamstring injury could rule him out. Predicted line-ups Real Madrid XI: Courtois; Carvajal, Rudiger, Alaba, Camavinga; Valverde, Modric, Kroos; Rodrygo, Benzema, Vinicius Jr. Manchester City XI: Ederson; Walker, Dias, Akanji; Stones, Rodri; Silva, De Bruyne, Gundogan, Grealish; Haaland. Odds Real Madrid win 9/4 Draw 47/17 Manchester City win 5/4 Prediction A draw leaves things intriguingly poised ahead of the second leg. Real Madrid 2-2 Manchester City Read More Why Man City vs Real Madrid is the ‘real’ Champions League final The six types of Pep Guardiola full-back, and what each says about Man City’s evolution Pep Guardiola ready to stare down his managerial nemesis once again

Adults who spend a large part of their day engaging in sedentary behaviors are more prone to dementia, a new study finds. The research, published on Monday in the journal JAMA, found that people aged 60 and older who spend over 10 hours a day engaging in behaviors like sitting while watching TV or driving could be at increased risk of developing dementia. Scientists, including those from the University of Southern California say, the findings are concerning since Americans on average are sedentary for about 9.5 hours each day. In the study, researchers assessed the data from about 50,000 adults over the age of 60 who had wrist-worn accelerometers to measure their movement for 24 hours per day for a week. The individuals did not have a diagnosis of dementia at the start of the study, scientists noted. They then used a machine-learning algorithm to analyse the dataset of accelerometer readings and classify behaviors based on different intensities of physical activity. Using the AI system, scientists could differentiate between different types of activity and sleeping – providing an objective measure of the time each person spent engaging in different types of sedentary behaviors. After an average of six years of follow-up, researchers used hospital records and death registry data to determine dementia diagnosis, and found 414 participants had the neurological condition. Scientists then adjusted for factors such as age, sex, education level, race/ethnicity, chronic conditions, genetics as well as lifestyle characteristics like physical activity, diet, smoking and alcohol use, self-reported mental health. They found that sedentary behavior was linked with increased risk of dementia among the participants. However, they found that certain amounts of sedentary behavior was not associated with dementia. “We were surprised to find that the risk of dementia begins to rapidly increase after 10 hours spent sedentary each day, regardless of how the sedentary time was accumulated,” study author Gene Alexander from the University of Arizona said. “This suggests that it is the total time spent sedentary that drove the relationship between sedentary behavior and dementia risk, but importantly lower levels of sedentary behavior, up to around 10 hours, were not associated with increased risk,” Dr Alexander added. Researchers call for more studies to establish causality and whether physical activity can mitigate the risk of developing dementia. The findings, according to scientists, “should provide some reassurance to those of us with office jobs that involve prolonged periods of sitting, as long as we limit our total daily time spent sedentary”. Read More What it’s like having Menopause Brain in a millennial office Josh Duhamel and wife Audra Mari announce they’re expecting first baby together Woman warns not to ignore symptoms after hot flushes lead to leukaemia diagnosis Poor metabolic health ‘linked with 12% higher risk of dementia later in life’ Sleeping pill could reduce levels of Alzheimer’s proteins Daily aspirin dose can help prevent diabetes in older people, scientists say

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There's 14 winners of the Champions League, or the old European Cup, in the 32-team group stage draw Thursday

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