Britain’s medicines regulator has authorized the world’s first gene therapy treatment for sickle cell disease, in a move that could offer relief to thousands of people with the crippling disease in the U.K. In a statement on Thursday, the Medicines and Healthcare Regulatory Agency said it had approved Casgevy, the first medicine licensed using the gene editing tool CRISPR, which won its makers a Nobel prize in 2020

Two people died and one was missing on Monday after heavy rains lashed Spain, triggering flash floods that forced the closure of Madrid metro...

UK Chancellor Jeremy Hunt said the government is committed to producing steel in Britain after a report of

Chelsea were still negotiating with Brighton for Moises Caicedo into the early hours of Saturday morning, but the ongoing delay could yet work in Liverpool’s favour in a multi-layered saga that has also seen both clubs also compete for Southampton’s Romeo Lavia. Liverpool went higher than Chelsea in Thursday’s effective auction for Caicedo, bidding £110m, which then saw the Stamford Bridge club go to £55m for Lavia. Chelsea are trying to do both deals, but there is some skepticism whether they can make the two work under Financial Fair Play without significant sales. This led to a late offer of players on top of a fee for Caicedo, but Brighton were not interested in any part exchange as of early Saturday morning. The fluid nature of the situation was illustrated in how Chelsea dropped interest in Leeds United’s Tyler Adams despite the player travelling to London in what was supposed to be a £20m deal. In another twist, Brighton are themselves interested in the US international, as well as Ajax’s Mohammed Kudus. The latter deal has not yet taken place due to a disagreement over a release clause should the Ghanaian sign. Such moves are being made as Brighton prepare to sell Caicedo, and manager Roberto De Zerbi has already confirmed he is now working on his team without the Ecuadorian in his plans. That has increased Liverpool’s chances the longer Chelsea go without a deal. While the preference from the player’s camp has been to go to Stamford Bridge, and Liverpool do not have a concrete agreement, Caicedo’s main intention is just to play for a top club. The Anfield club have not pulled out of the deal despite reports.It forms another subplot to Sunday’s meeting between Chelsea and Liverpool at Stamford Bridge. Read More Premier League LIVE: Chelsea offer player swap to hijack Liverpool’s Moises Caicedo deal plus Harry Kane latest Moises Caicedo transfer takes twist as Chelsea look to hijack Liverpool offer Liverpool, Moises Caicedo, and the £100m bid that Jurgen Klopp said he’d never make Liverpool, Moises Caicedo, and the £100m bid that Jurgen Klopp said he’d never make Moises Caicedo transfer takes twist as Chelsea look to hijack Liverpool offer Jurgen Klopp urges caution over Liverpool’s move for Moises Caicedo

A UK court on Monday began hearing a lawsuit brought by Donald Trump over a salacious dossier compiled by a former British MI6 agent that contained...

Seth Meyers takes a closer at Trump facing new legal developments in three separate cases across the country

Brianna Lafoe, aged 19, and Sierrah Newell, aged 20, were apprehended outside the Coyote Ugly Saloon on September 14

EU leaders meeting in Brussels Friday discussed bolstering support for Ukraine, as they strived to focus on helping that country against Russia's invasion even as...

Palestinian militants fire barrages into Israel after it targets Islamic Jihad rocket launchers.

In Apex Legends, movement is king. One of the newest movement tricks involves Rampart and her A-Walls. This new trick allows her to superglide in Apex, allowing you to get a speed boost past enemies and practically break their ankles. Here's how to do it.

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Michael Block continues to wow fans.