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So you’ve been counting down to your holiday – when you’ll finally have the chance to step off the hamster wheel and relax. Except, no sooner have you checked in at your hotel than you find yourself reaching for the headache pills or tissues, as a niggling cold or migraine takes hold. Sound familiar? If it feels like you suddenly get unwell when you finally hit the pause button, you’re not imagining it – there’s even a medical term for it. The ‘let-down effect’ “This is known as the ‘let-down effect’,” says Dr Suhail Hussain, a personal physician and private home visiting GP. “When the body is used to functioning on high levels of [stress hormones] cortisol and adrenaline and they suddenly decrease, our immune system is exposed and then we’re prone to minor infections and excessive tiredness. “Pain and muscle aches also increase – adrenaline increases muscle tension, so imagine a rubber band always pulled tight, what happens when you let go? “There may also be a spike in mental health problems, such as acute anxiety and panic attacks. Flare-ups in pre-existing chronic conditions is also a common phenomenon, for example migraine and asthma attacks,” he adds. The ‘let-down effect’ can strike after a brief period of intense stress, such as after exams or completing a project, and after positive high-stress events, like planning a wedding. And for many people, it hits when you finally get to put down your to-do list and go on holiday. What’s the deal with stress hormones? Stress hormones serve an important purpose and we need them to function, so they’re not always bad news. “Basically, we are programmed to respond to danger – ‘fight or flight’ – so in stressful situations, there is an increase in levels of stress hormones adrenaline and cortisol,” Dr Hussain explains. “Together, these two hormones control mood, motivation and fear. In periods of stress or heightened anxiety, adrenaline levels rise – causing an overdrive of the sympathetic nervous system, resulting in racing pulse, high blood pressure, sweating, etc.” Stress hormones also play a role in regulating inflammation, metabolising nutrients, and aiding immune function, sleep and energy. But ideally, they wouldn’t stay at raised levels for too long. “If these hormones are always ‘on’, then inflammatory processes are accelerated and your immune system is impaired,” says Dr Hussain. “Consistently high levels of cortisol in your blood can lead to inflammation and a weakened immune system.” Can you avoid the ‘let-down effect’? Dr Hussain says: “You can try to lessen the impact of the ‘let-down effect’ by de-stressing slowly. Instead of crashing and burning, try to maintain a bit of activity on the holiday or some degree of exercise, such that there’s not a massive decrease in stress hormone levels, meaning you can allow the body to acclimatise slowly.” But not getting sick on holiday may not be the only concern here. If your body is giving you warning signs that chronic stress is taking a toll, it’s important to listen. “Constantly running on high levels of stress is very bad for you. It leads to the problems mentioned above but also longer-term consequences, such as plaque formation in arteries, leading to coronary events and strokes, depression and anxiety, and even addiction. Levels of obesity are also increased,” explains Dr Hussain. He says indications to look out for could include: “Recurrent illnesses, feeling tired, lack of energy. Poor response to glucose, leading to type 2 diabetes, elevated blood pressure and disruption of the sleep-wake cycle.” If you have any concerns, check in with your GP. And Dr Hussain suggests finding ways to make managing stress in everyday life. “Build in regular relaxation to your daily schedule. Get out to walk, spend time in the sun, observe nature. Listen to relaxing music. Make a regular sleep schedule, read, spend time with family and loved ones,” he says. “Don’t just work and work and work for the expectation of a big holiday at the end of it.” Read More Charity boss speaks out over ‘traumatic’ encounter with royal aide Ukraine war’s heaviest fight rages in east - follow live As Katie Boulter takes Wimbledon by storm, we look at her best on-court fashion so far Lioness Katie Zelem: Nerves are good – it’s just about channelling them the right way Church of England should scrap fees of up to £641 for weddings, vicar says

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If you thought Adam22 had been put off watching his wife sleep with other men, you’d be sorely mistaken. The YouTuber, has revealed that he’d not only encourage the mother of his child, Lena the Plug, to film a sex scene with another guy, but he’d also like to get in on the action – and has a candidate in mind. The ‘No Jumper’ host (real name Adam Grandmaison) was speaking to actor Michael Rapaport for his ‘I Am Rapaport’ podcast when he opened up about their X-rated plans. The interview came as the dust continued to settle following Lena’s now-notorious encounter with porn star Jason Luv. Sign up for our free Indy100 weekly newsletter Their tryst marked the first time the OnlyFans star (real name Lena Nersesian) had shot adult content with a man other than her husband. And although the couple initially celebrated the film as a big success, things suddenly turned sour when Luv publicly boasted that he was “obviously” a better lover than Adam. The podcaster responded by announcing that the porn legend was “officially blacklisted from smashing [his] wife again” and ominously threatening to “expose” him. However, a week on, he seemed to have calmed down a bit, and told Rapaport that he was up for round two – just not with Luv. Admitting that he enjoyed watching the video of Lena and Luv’s love-in, Adam stressed: “We definitely want to do more”. He then clarified, somewhat more explicitly, that his wife had told him: “I want to get f**ked by you and another dude.” “Of course we're going to film it,” he confirmed. “But she's into that idea and everything and I'm definitely into it too.” Rapaport then pressed the ‘PlugTalk’ presenter to reveal who they had in mind for their new NSFW venture. “It’s almost like the f**king NBA draft,” the interviewer joked. “Who’s going to be the number one draft pick?” However, Adam replied that they didn’t have a huge number of options, given that “not that many dudes in porn have a brand about them” or a “sizeable social media platform”. (In other words, most eligible contenders aren’t influential enough for this ambitious pair.) But Rapaport was determined to get a name out of the content creator so, eventually, Adam conceded. “Johnny Sins,” he said, before describing him as “pretty much like the most popular white porn star”. “He's somebody that we've talked about having her shoot with, but then I'm friends with a lot of guys,” he added. Adam then explained that he and Lena “are thinking about making a YouTube video or a piece of content in which we interview a bunch of different guys to try to figure out who we like vibe-wise”. It sounds to us like some kind of X-rated X-Factor, and we’re sure plenty of people would be into it, especially if the success of their show ‘Plug Talk’ is anything to go by. Still, the podcaster acknowledged that they wanted to tread carefully given the fallout from their Luv liaison. “The Jason thing seemed good – he seemed like he was a great candidate for this – until he started running his mouth a little bit too much on that other podcast he did,” Adam said, adding: “That kind of soured the vibe for us.” He admitted: “We were thinking about doing me, Lena and him together at a certain point, but then I feel like it kind of got ruined by him just not being able to handle the clout.” Rapaport then revealed that he’d watched Lena and Luv’s infamous movie himself and that he “wasn't really that impressed with the whole thing”. Defending his wife, Adam insisted: “It was her first time shooting with a different guy, she was a little on edge. She said that she felt real guilty the whole time. She was kind of nervous and stuff. So I feel like she'll probably improve a lot from here.” He then acknowledged that Luv “didn't go as crazy as a lot of people wanted him to” but accepted that this was “probably good from [his] perspective”. “You don't really want to see your girl getting completely manhandled on camera for the first time,” he said. “I see how some of these male porn stars are f**king girls and they're really taking charge. I don't know if I was ready for that, and I didn't really think about that beforehand.” Rapaport encouraged Adam to become the “Simon Cowell” of porn and give some young, inexperienced “d**k-slinger” their big break by taking them on for the project. The adult entertainer recognised that there was certainly a lot of interest around a potential collaboration, telling his host that he was being flooded with DMs. “Every male porn star's just tapping in with me, like, ‘Hey, I would love to be her next scene’,” he said. “[It’s nice that they're reaching out to me as opposed to just reaching out to her, which some of them are [...] and I’m not super into that,” he stressed. However, for anyone hoping for the swift release of a spicy threesome, you may have a while to wait. “We're trying to move slowly with it and just let the heat from the first scene that she dropped cook for a while before we do it,” Adam said. “But yeah, definitely, we've got some wild stuff in the works.” Have your say in our news democracy. Click the upvote icon at the top of the page to help raise this article through the indy100 rankings.

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U.S. job openings rose unexpectedly in April a sign the American labor market remians surprisingly resilient as the Federal Reserve pushes interest rates higher to combat inflation

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