
The mojo the Steelers' offense showed in the preseason is gone. Getting it back could be difficult
The Pittsburgh Steelers are 1-1 after a victory over Cleveland but have plenty to work on, particularly on offense
2023-09-20 03:19

Naomi Watts' ex Liev Schreiber hailed for 'incredibly sweet' gesture as actress marries BF Billy Crudup
'The high road always has the better view. Beautiful comment, Liev,' a fan commented on Naomi Watts' picture
2023-06-12 18:53

Nazi Barbs in Bavaria Revive Germany’s Struggles With Its Past
In downtown Munich, police cars blocked roads to a modern office building where security guards patrolled the halls
2023-09-30 15:30

European lawmakers try to balance protection and privacy with law on explicit images of children
European Union lawmakers have adopted a series of amendments to a draft law that is intended to keep sexually explicit photos and videos of minors from circulating online
2023-11-15 04:34

Groundbreaking migraine treatment offers ‘new hope’ for patients
A treatment for acute migraines has been approved for NHS use for the first time, with experts saying the move could be a “step-change” for thousands of people who suffer from the condition. The National Institute for Health and Care Excellence (Nice) said its final draft guidance on Rimegepant “addresses the high unmet need for treatment options for acute migraine”. Rimegepant, also known as Vydura and made by Pfizer, will be available to adults who have tried at least two triptans – medication usually given to tackle headaches or migraines – but found they did not work well enough. It can also be administered to those who are not able to take triptans or have an intolerance, or patients who have tried nonsteroidal anti-inflammatory drugs (NSAIDs) and paracetamol. Helen Knight, director of medicines evaluation at Nice, said: “Migraine is a condition described in comments to Nice from carers and people with migraine as an invisible disability that affects all aspects of life including work, education, finances, mental health, social activities and family. “Today’s final draft guidance addresses the high unmet need for treatment options for acute migraine, once again demonstrating our ability to ensure clinically and cost-effective medicines are available to those who need them as quickly as possible.” Rimegepant is taken as a wafer, which dissolves under the tongue and works by stopping the release of a protein around the brain called calcitonin gene-related peptide. In July, the medicine was recommended as an option for preventing episodic migraines in adults who have at least four and fewer than 15 attacks per month if “at least” three other treatments have not worked. This is the first and only Nice-recommended medicine that can help alleviate the misery of acute migraines, and may be considered a step-change in treatment Helen Knight, Nice Under the latest guidance, it will also be used to relieve symptoms of a migraine, which can include pain, nausea and sensitivity to light, but also painless symptoms such as temporary visual disturbances known as “aura”, which Nice said “is not well managed with existing treatments”. The recommendation is expected to benefit about 13,000 people. Ms Knight added: “This is the first and only Nice-recommended medicine that can help alleviate the misery of acute migraines, and may be considered a step-change in treatment.” Migraine is an incredibly misunderstood condition that can have a significant impact on all areas of life, including ability to work, maintain relationships and mental health Robert Music, The Migraine Trust Robert Music, chief executive of The Migraine Trust, said the Nice guidance “provides people with migraine valuable options to help reduce the pain and length of a migraine attack”. “It brings new hope,” he added. “It will especially benefit those who have not found a treatment that works, those who get debilitating side effects – including medicine overuse headache – from them, and those with cardiovascular disease who cannot take existing treatments. “Migraine is an incredibly misunderstood condition that can have a significant impact on all areas of life, including ability to work, maintain relationships and mental health.” Read More NHS winter resilience fund announced by Government NHS reliance on paper notes ‘stopping trusts from realising full potential’ Recession fears as UK economy shrinks by more than expected in shock decline Charity boss speaks out over ‘traumatic’ encounter with royal aide Ukraine war’s heaviest fight rages in east - follow live
2023-09-14 11:31

'How would people like me know about sex?' Young people are losing judgment-free spaces to learn about sex and sexuality
Teenagers in India and across Asia-Pacific are turning to social media platforms for judgement-free, engaging information about sex, sexuality and pleasure. But content creators say their posts are falling foul of moderation guidelines that don't distinguish between edutainment and pornography.
2023-10-11 12:00

Seattle climate activists roost in old cedar tree to prevent it from being cut down for new housing
Activists in Seattle climbed up a tree to prevent its removal on a construction site for new homes
2023-07-22 05:27

Deva Cassell has been 'inspired' by fashion since she was a child
Monica Belluci and Vincent Cassell's 19-year-old daughter Deva Cassell has been "inspired by the world of fashion since" childhood and loves being a brand ambassador of Maria Grazia Chirui's Dior.
2023-12-01 19:00

The best gifts for men: 63 awesome options for every type of guy
Remember: The best gifts for men should make the guy you're buying a gift for
2023-10-31 22:06

Who is Joseph Czuba's wife? Illinois landlord accused of killing six-year-old Wadea Al-Fayoume was paranoid about Hamas 'day of jihad'
Illinois landlord Joseph Czuba stands accused of stabbing six-year-old Wadea Al-Fayoume and his mother, Hanaan Shahin
2023-10-17 18:54

Marvel Unlimited and Fortnite Partnership Explained
Marvel and Fortnite continue their partnership by rewarding Marvel comic readers with in-game items.
1970-01-01 08:00

Who was Colin M Smith? Restaurant server stabbed to death while defending his friend from homophobic slurs
The suspect directed homophobic slurs and behaved inappropriately toward a member of Colin M Smith's group of friends
2023-07-16 04:13
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