The Texas Rangers captured the World Series for the first time in the team's 63-year history on Wednesday, defeating Arizona 5-0 to complete...

Microsoft has created its first-ever edible Xbox controller. The novelty gaming accessory is not functional;

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Women with myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) tend to have more symptoms and co-occurring conditions than men, according to the world’s largest study of the disease. The study, entitled DecodeME, reveals women who have the condition for more than 10 years are more likely to experience increasingly severe symptoms as they get older. ME/CFS is estimated to affect more than 250,000 people in the UK, of all ages and from all social and economic backgrounds. Its key feature, called post-exertional malaise, is a delayed dramatic worsening of symptoms following minor physical effort. Other symptoms include pain, brain fog and extreme energy limitation that does not improve with rest. Causes are unknown and there is currently no diagnostic test or cure. Experts from the University of Edinburgh analysed anonymous survey questionnaires from more than 17,000 people with ME/CFS. Two-thirds of women, and slightly more than half of men, reported at least one active co-occurring condition. Similarly, 39.2% of women and 28.6% of men reported at least one inactive co-occurring condition. We discovered that the disease is worse for women, in older people, and many years after their ME/CFS started Professor Chris Ponting of the University of Edinburgh A condition was considered active if the participant had experienced symptoms in the preceding six months. The most common active co-occurring condition was irritable bowel syndrome, with clinical depression, fibromyalgia, anaemia and hypothyroidism also featuring prominently. Women also reported, on average, more symptoms than men – 42 compared with 36. The most common of these symptoms were brain fog – a term commonly used to describe the cognitive impairment experienced by participants – unrefreshing sleep and muscle pain. These findings highlight the very serious impact ME/CFS has on women who are disproportionately affected Sonya Chowdhury, chief executive of Action for M.E Participants were also asked to define the severity of their illness from mild to very severe using definitions from the UK’s National Institute for Health and Care Excellence guidelines. Experts identified that being a woman and having ME/CFS for more than 10 years are risk factors for severe illness, with symptoms increasing in intensity as they age. Professor Chris Ponting, study lead from the MRC human genetics unit at the University of Edinburgh’s Institute of Genetics and Cancer, said: “ME/CFS is a devastating disease affecting a UK population the size of Derby. “We discovered that the disease is worse for women, in older people, and many years after their ME/CFS started. “Our hope is that DecodeME’s genetic results will shed light on why certain groups are more susceptible to ME/CFS than others.” Sonya Chowdhury, chief executive of Action for M.E. and chair of the management group of the study, said: “These findings highlight the very serious impact ME/CFS has on women who are disproportionately affected. “It’s important to also recognise the impact that it has on men who have ME/CFS and we thank the 20,000 men and women who have already signed up to take part in this very important study. “We still need more to join us, so if you are 16 or older, live in the UK and have a diagnosis of ME/CFS, please do take part now to help us decode ME at www.decodeme.org.uk/portal.” Read More Charity boss speaks out over ‘traumatic’ encounter with royal aide Ukraine war’s heaviest fight rages in east - follow live 4 hacks to get teens off the sofa and get active – as study warns of heart damage Taking adult education classes may lower risk of dementia, study suggests Indiyah Polack: I didn’t want to go on Love Island because of my acne

Apple will stop using leather, it has announced. It will offer no new products using materials taken from animals, it said. That includes iPhone cases and Watch bands, both of which make heavy use of leather. Lisa Jackson, Apple’s vice president of environment, policy and social initiatives, noted that leather is a popular material for accessories. But it has considerable environmental impact, she noted, especially at the scale that Apple uses it. As such, it has committed to phasing out those materials. Instead, it will rely on new materials that have been especially developed. For the Apple Watch’s sport loop, for instance, it has changed the material to use 82 per cent recycled yarn. For the straps that are currently made out of leather, it will rely on a new seemingly custom developed material called “FineWoven”. That will presumably also be used for the cases made for the new iPhone 15. And Apple has developed new straps with Nike and Hermès. The latter collaboration has relied heavily on leather – but recently Apple has been rumoured to be selling off those products cheaply. The new materials will help make the new Apple Watch Series 9 the first carbon neutral product the company has made. Read More Here’s the brand new Apple Watch Apple is about to reveal the new iPhone – and a lot more Here’s when you will actually be able to get the new iPhone

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A cyber attack targeting the British Library has led to a leak of employee data, the institution said. The Rhysida ransomware group has claimed it has access to passports along with other data files. The group said it has started bidding in an auction for access at 20 bitcoin (around £600,000) on an online site. The British Library, which has one of the largest book collections in the world, previously reported that a “major technology outage” had hit online services, public wifi at the site and its website. Ransomware is the key cyber threat facing the UK, and all organisations should take immediate steps to limit risk by following our advice on how to put in place robust defences to protect their networks National Cyber Security Centre spokesperson It said in October that the National Cyber Security Centre (NCSC) and cybersecurity specialists were investigating. On Tuesday, an NCSC spokesperson said: “We are working with the British Library to fully understand the impact of an incident. “Ransomware is the key cyber threat facing the UK, and all organisations should take immediate steps to limit risk by following our advice on how to put in place robust defences to protect their networks.” The British Library, near St Pancras railway station, remains open and visitors can access the reading rooms for personal study. On Monday, the library posted a statement to X confirming internal HR files had been leaked. It said: “We’re continuing to experience a major technology outage as a result of a cyber-attack, affecting our website, online systems and services, and some onsite services too. “We anticipate restoring many services in the next few weeks, but some disruption may persist for longer. “Following confirmation last week that this was a ransomware attack, we’re aware that some data has been leaked. This appears to be from our internal HR files. “We have no evidence that data of our users has been compromised.” The Information Commissioner’s Office (ICO), the UK’s data protection watchdog, has confirmed it is looking into the breach. An ICO spokesperson said: “The British Library reported an incident to us and we are making inquiries.” Last week, the Federal Bureau of Investigation (FBI), Cybersecurity and Infrastructure Security Agency (CISA), and the Multi-State Information Sharing and Analysis Centre (MS-ISAC) warned about Rhysida. In a joint statement they said the group has launched attacks “against the education, healthcare, manufacturing, information technology, and government sectors since May 2023”.

The Knicks could end up with a huge star, 2 centers just became available in free agency and KPJ could be done in the NBA in today's NBA news roundup