China drugmakers axe IPO plans as they face scrutiny in anti-graft drive
By Jason Xue and Tom Westbrook SHANGHAI A growing number of healthcare companies in China are shelving their
2023-08-11 14:48
The M1 MacBook Air is back at its all-time low price
SAVE $249.01: The ultra-popular M1 MacBook Air with 256GB of built-in storage is back down
2023-07-20 23:12
Reform-minded prosecutors in northern Virginia win reelection nominations in Democratic primaries
Three incumbent prosecutors in northern Virginia who faced tough challenges after being elected four years ago on a progressive reform agenda have won their Democratic primaries
2023-06-21 11:44
Nicolas Cage is coming to horror game 'Dead by Daylight,' because sure, why not
Multiplayer horror game Dead by Daylight is adding Nicolas Cage. Why? We don't ask those
2023-05-18 13:14
'Alien spacecraft' found at the bottom of Pacific Ocean
For years people have been looking to the skies for signs of alien life - but maybe, they should have been looking at the bottom of the ocean this whole time. A Harvard physicist has claimed that parts of an alien 'spacecraft' could have been uncovered under the sea. Professor Avi Loeb set off on a search along the bottom of the Pacific Ocean and found 50 iron pieces which originated from the IM1 meteor. IM1 crashed off the coast of Papua New Guinea and Leob believes it could contain key information in the search for life out there in the universe, saying he hasn’t discounted the idea of the pieces being evidence of a “spacecraft” from an “extraterrestrial technological civilization” which crashlanded on Earth. Sign up to our free Indy100 weekly newsletter Loeb is currently the head of Harvard’s Galileo Project, focusing on the search for aliens, and he said the fragments they found must have come from “a natural environment different from the solar system, or an extraterrestrial technological civilization.” Speaking to Fox News Digital, Loeb detailed his thoughts on the origins of the meteor fragments by saying: “Given IM1's high speed and anomalous material strength, its source must have been a natural environment different from the solar system, or an extraterrestrial technological civilization.” He added that IM1 “is actually tougher and has material strength that is higher than all the space rocks that were catalogued by NASA. That makes it quite unusual.” Have your say in our news democracy. Click the upvote icon at the top of the page to help raise this article through the indy100 rankings.
2023-06-29 21:19
Google AI breakthrough represents huge step in finding genes that cause diseases, scientists say
Google says it has made a significant step in identifying disease-causing genes, which could help spot rare genetic disorders. A new model named AlphaMissense is able to confidently classify 89 per cent of all possible “missense” variants in genes, identifying whether they are likely to cause diseases or benign. That compares with just 0.1 per cent of all missense variants that have been confidently classified by human experts. Missense variants happen when a single letter is substituted in the DNA, which in turn leads to proteins with a different amino acid. That small change can have significant effects – Google likened it to the way that changing a letter in one word can change the meaning of the whole sentence. Most of those variants are benign: the average person has more than 9,000 of them. But some of them can be disastrous, leading to rare genetic diseases. The new AlphaMissense looked at existing information about missense variants, and how commonly they are seen in humans and closely-related primates. It looked for those that were rarely seen, classifying them as pathogenic, and from that was able to use that information to analyse other protein sequences – giving not just a verdict on whether they were likely to cause problems, but also how confident it was. Experiments, conducted by humans, which look to find those mutations are expensive and slow: they require people to examine each unique protein and designed separately. Google says that the new system means that researchers can “preview” those results for thousands of proteins at a time, helping them decide where to focus. The company has used its systems to release a vast catalogue of “missense” mutations, so that researchers can learn about what effect they have. In some cases, those variations can lead to conditions such as cystic fibrosis, sickle-cell anaemia, or cancer, and understanding them could be key to researchers studying ways to treat or prevent those diseases. It is just the latest health breakthrough from Google’s Deepmind division, which is looking to use artificial intelligence to both identify and treat a variety of conditions. The new system was built on AlphaFold, the breakthrough model that helped unfold proteins, the building blocks of life. The research is described in a new paper, ‘Accurate proteome-wide missense variant effect prediction with AlphaMissense’, published in the journal Science. The catalogue is being made “freely available to the research community”, Google said, and the company will release the code behind the AI system. Read More BBC removes some Russell Brand content as monetisation suspended on YouTube Google Bard can now link to Gmail and other apps to help with responses Long-form video content is here to stay, says YouTube UK boss
2023-09-20 00:05
Alonso to give Leverkusen fans 'a night to remember' against Roma
Bayer Leverkusen manager Xabi Alonso said he wanted to give the team's fans something to remember for years in Thursday's Europa League semi-final second...
2023-05-17 20:23
Barr says he believes Trump 'knew well he lost the election'
Former Attorney General Bill Barr said Wednesday that he believes Donald Trump "knew well he lost the election," speaking to CNN on the eve of the former president's arraignment in the special counsel's probe into 2020 election interference.
2023-08-03 12:14
MLB Rumors: Another Blue Jays star mentioned in trade talks alongside Bo Bichette
Does trading star talent make sense with the Blue Jays in the hunt for Shohei Ohtani?
2023-11-29 07:26
Burger hits go-ahead homer as White Sox beat Braves 6-5 for first win in Atlanta
Jake Burger’s sixth-inning homer off Spencer Strider gave Chicago the lead, Andrew Benintendi drove in three runs with three hits and the White Sox beat the Braves 6-5 for their first win in Atlanta
2023-07-16 10:09
NY Democrat Accused of Pulling Fire Alarm During Shutdown Talks
A fire alarm went off in a Capitol Hill building Saturday, adding to the chaos as US lawmakers
2023-10-01 03:57
Warriors youth campers help present former Golden State players Bjelica, Chiozza championship rings
The Golden State Warriors typically present former players with their championship rings in an on-court pregame ceremony when they come through town with an opposing organization, but for Nemanja Bjelica and Chris Chiozza they were playing overseas so the first opportunity came during a special moment at Warriors youth camp
2023-07-20 07:28
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