Donald Trump used his platform on CNN to lash out at E Jean Carroll just a day after a jury found that he had sexually abused and defamed the former journalist. Ms Carroll, 79, sued the former president for raping her in a dressing room at a Bergdorf Goodman in New York in 1996, and then “destroying” her reputation when he claimed she was lying. The jury didn’t find Mr Trump liable of raping Ms Carroll, but it found the one-time president more likely than not sexually abused Ms Carroll. Mr Trump was also found liable for defamation and awarded her a total of $5m. The twice-impeached president mocked Ms Carroll at the CNN town hall that aired just a day after the verdict. The town hall has been severely criticised as divisive and even being “a volcano of bulls***” by commentators who accused the network of providing Mr Trump a platform for airing several dubious claims. He described her as a “whack job” and called the trial “rigged”. He was asked what he would tell voters who said the verdict disqualifies him from being president. “Well there aren’t too many of them because my poll numbers just came out – they went up,” Mr Trump said to the crowd which, according to CNN, was composed of Republicans and undecided voters. The former president also called Ms Carroll’s allegations a “made-up story”. “I swear on my children, which I never do, I have no idea who this woman – this is a fake story, a made-up story,” he said. Mocking her, he said he was too famous to hang around department stores. Ms Carroll had told the jury in her testimony that she and Mr Trump had engaged in playful banter after a chance encounter at Bergdorf Goodman one evening in the mid-1990s. But after taking an escalator up to a deserted 6th floor to look for lingerie, Mr Trump led her to a dressing room, pushed her up against a wall and sexually assaulted her. “I was very famous then and I owned the Plaza Hotel right next door and I owned the buildings around it – I’m not going into a dressing room of a crowded department store,” he said at the town hall. He also reiterated claims he did not know Ms Carroll at all, and called the trial “rigged.” “She wasn’t raped, OK? … And I didn’t do anything else either, OK, because I don’t know who the hell she is,” he said during the town hall, as the audience was heard laughing. Earlier on Tuesday after the verdict, Mr Trump had falsely claimed he “wasn’t able to defend” himself in the trial after he rejected an offer to testify. On Tuesday morning, the former president wrote on Truth Social that he was “waiting for a jury decision on a False Accusation where I, despite being a current political candidate and leading all others in both parties, am not allowed to speak or defend myself, even as hard nosed reporters scream questions about this case at me”. Read More Five key takeaways from CNN’s divisive town hall with Donald Trump E Jean Carroll reveals she was ‘shaken’ throughout Trump civil rape trial before ‘overwhelming’ verdict CNN’s anchors and insiders lead horrified reaction to Trump town hall: ‘We’re going to get crushed’ Ivanka and Jared split over attending Trump 2024 launch – follow live Why was Donald Trump impeached twice during his first term? Four big lies Trump told during his 2024 presidential announcement

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Alcohol addiction ruins millions of lives every year, but scientists may have found a cure for this terrible affliction. A new treatment for alcohol use disorder (AUD) has been trialled in monkeys with impressive results and, if these translate to human trials, the impact could be monumental. A team of neuroscientists and physiologists from across the US tested a new type of gene therapy to see if they could directly target the underlying brain circuitry associated with sustained heavy drinking. As they noted, in the journal Nature Medicine, people suffering from AUD commonly return to alcohol use even if they attempt to quit. This is largely to do with what’s known as mesolimbic dopamine (DA) signalling – meaning how the central nervous system circuit communicates the feelgood neurotransmitter dopamine. A protein called glial-derived neurotrophic factor (GDNF) is key to keeping these neurons in this reward circuitry functioning. However, experts have found that levels of GDNF are reduced in people with AUD during periods of alcohol abstinence, most notably in a region of the brain called the ventral tegmental area (VTA), as IFLScience notes. Therefore, the researchers decided to test whether using gene therapy to deliver more GDNF to the VTA could help reinforce this crucial dopaminergic signalling and prevent patients from suffering an alcoholic relapse. The team of scientists explained how alcohol consumption in non-addicts prompts the release of dopamine, creating a pleasurable buzz feeling, but chronic alcohol use causes the brain to adapt and stop releasing so much dopamine. “So when people are addicted to alcohol, they don’t really feel more pleasure in drinking,” Dr Kathleen Grant, a senior co-author of the study, said in a statement. “It seems that they’re drinking more because they feel a need to maintain an intoxicated state.” For their research, Dr Grant and her colleagues used eight rhesus macaque monkeys, who were exposed to increasing concentrations of alcohol over four 30-day “induction” periods. The monkeys then had free access to alcohol and water for 21 hours a day for six months, during which they developed heavy drinking behaviours. This was then followed by a 12-week abstinence phase, with the GDNF treatment performed four weeks in for half of the subjects. The gene therapy was delivered using a a viral vector containing a copy of the human GDNF gene injected directly into the primate’s VTA, according to IFLScience. And the results were truly jaw-dropping. “Drinking went down to almost zero,” Dr Grant said. “For months on end, these animals would choose to drink water and just avoid drinking alcohol altogether. They decreased their drinking to the point that it was so low we didn’t record a blood-alcohol level.” The most exciting aspect of their findings is the suggestion that gene therapy could offer a permanent solution for people with the most severe cases of AUD. This will be a welcome glimmer of hope to many, given that some 29.5 million people were diagnosed with AUD in the US alone in 2021, according to the National Institute on Alcohol Abuse and Alcoholism. Of these 29.5 million sufferers, almost a million (894,000) were aged between 12 and 17. It’ll likely be some time before we know for sure whether the gene therapy can be rolled out in humans, but it’s an important first step in tackling this devastating disorder. Sign up for our free Indy100 weekly newsletter Have your say in our news democracy. Click the upvote icon at the top of the page to help raise this article through the indy100 rankings.

Former president Donald Trump began his weekend by lashing out against his long list of enemies, ranting on Truth Social about Biden family conspiracies, the federal indictment against him, and perceived disloyalty at Fox News. The outburst comes after a week of embarassment. On Tuesday, Mr Trump visited the iconic Versailles restaurant in Miami after being arraigned on 37 federal charges and bombastically announced that there would be “food for all.” There was just one problem: according to a report in the Miami New Times, Mr Trump never picked up the tab… Mr Trump’s visit to the Cuban restaurant functioned largely as a campaign stop after he spent the morning in federal court on charges that he mishandled classified documents and impeded the government’s attempts to get them back. The fallout from his arraignment that day continues, with fellow Republicans torn over how to respond to the party’s defacto leader being charged with federal crimes. Read More Trump declared ‘food for all’ in post-arrest stop at Miami cafe – but reportedly skipped bill Donald Trump scores rare legal win as DA drops golf course tax probe Trump's promise of payback for prosecution follows years of attacking democratic traditions Is Donald Trump going to prison?