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There are more than 47,000 men diagnosed with prostate cancer every year in England but new research says using MRI scans can reduce deaths caused by the disease. Current tests usually detect the level of the protein prostate-specific antigen (PSA) in the blood, but scientists say this has meant overdiagnosis and overtreatment of low-risk cancer. The Reimagine study, by University College London, University College London Hospitals NHS Foundation Trust and King’s College London, invited 303 men aged between 50 and 75 to have a screening MRI and a PSA test. Of those men, 48 (16%) had an MRI that indicated prostate cancer despite having a median PSA density – 32 of those had lower PSA levels than the current screening benchmark, meaning they would ordinarily not have been referred for investigation. After NHS assessment 29 were diagnosed with cancer that required treatment, and three were diagnosed with low-risk cancer with no need for treatment. Prof Caroline Moore, consultant surgeon at UCLH, chief investigator of the study and NIHR research professor, called the findings “sobering”. She said: “Our results give an early indication that MRI could offer a more reliable method of detecting potentially serious cancers early, with the added benefit that less than 1% of participants were ‘over-diagnosed’ with low-risk disease.” What is prostate cancer? Prostate cancer is the UK’s most common male cancer. It affects the prostate – a walnut-sized gland that sits beneath the bladder and surrounds the urethra in people born with male sex organs. Its main purpose is to help produce semen (the fluid that carries sperm). Prostate cancer can develop when cells in the prostate start to grow in an uncontrolled way. While some prostate cancers grow quickly and spread, others grow too slowly to cause any problems and therefore will never need any treatment. What are the risk factors “Prostate cancer is a disease we tend to see in older age groups (over-50s), but there are exceptions, as with any form of cancer,” said Dr Sanjay Mehta, GP at The London General Practice. According to Prostate Cancer UK black men are at a higher risk – one in four black men will get prostate cancer in their lifetime (compared to one in eight for other men). The risk increases after the age of 45. Family history is important too; your father or brother has had prostate cancer or your mother or sister has had breast cancer, your risk is higher. What are the symptoms? Often there aren’t any signs in the early stages, so be aware of your own risk factors and chat to your doctor if concerned. Prostate Cancer UK have an online risk checker you can use too. Mehta said to watch out for urinary symptoms and changes to how you urinate. “So frequency, where you need to go more often. Hesitancy, where you’re standing over the toilet bowl and a period of time will pass before you’re able to pass urine, and ‘dribbling’, where you’ve finished but find you’re still passing when you walk away. “These are common in older men anyway. But if it’s new for you, and you find you’re having to go more often at night, and you’re having hesitancy or urgency, see your doctor.” Other things to get checked include erectile dysfunction, blood in your urine, and any new and unexplained lower back pain. “Then there are general systemic symptoms, like lethargy, lack of appetite,” added Mehta. “Again, these things often happen anyway, but if it’s a change for you and it’s been happening for a couple of weeks, see your doctor.” How is prostate cancer diagnosed and treated? First, your doctor will chat through your symptoms and history with you. “The next step would involve an examination, including a rectal examination of the prostate,” said Mehta, before referral for further investigations. “I appreciate this can put some men off seeing their doctor but it is a very helpful way of assessing things”. After diagnosis, treatment depends on the stage of the cancer and what’s suitable for each individual, but it may include surgery or radiotherapy. Caught early, prostate cancer is generally very treatable. And even with advanced prostate cancer, treatments have come a long way. Read More Charity boss speaks out over ‘traumatic’ encounter with royal aide Ukraine war’s heaviest fight rages in east - follow live Keep fit to avoid heart rhythm disorder and stroke, study suggests How to give your home a proper summer sort out What you really need to do in autumn to keep your lawn in shape

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Tyson Fury survived a knockdown and went on to beat Francis Ngannou in a controversial decision on Saturday night, avoiding a major upset. WBC heavyweight champion Fury squared off with Ngannou – a mixed martial artist and ex-UFC champion – in a professional boxing match in Saudi Arabia, with the Cameroonian stunning the Briton in Round 3 with a knockdown, clipping him on the top of the head with a fine left hook. Ngannou, 37, was making his boxing debut yet outfought Fury, 35, for much of the bout, as a stunned audience looked on in Riyadh. However, Fury avoided the first loss of his professional career when he was named a split-decision winner – 94-95, 96-93, 95-94. Ngannou was a massive underdog in the main event in Riyadh but produced a superb performance with immense discipline and aggression, and many figures in the world of boxing declared that the “Predator” had been denied a rightful win. After the fight, Oleksandr Usyk entered the ring to face off with Fury, whom he is contracted to fight next. Ukrainian Usyk, unbeaten like Fury, holds the unified heavyweight boxing titles. The pair have been rumoured to clash in Riyadh on 23 December, though Fury and his promoter Frank Warren played coy after the fight with Ngannou. “That definitely wasn’t in the script,” said Fury. “[Ngannou] is a lot better of a boxer than we thought he’d be. He’s a very awkward man, and he’s a good puncher, and I respect him a lot. He was very awkward, he wasn’t coming forward; he was waiting for me to throw my punches then looking to counter. “[The knockdown] is a part of boxing. I got caught behind the head. I got up and it was alright; I got back to my boxing. “I don’t know how close [the fight] was, but I got the win and that’s what it is. I’ve been out the ring a long time again. You can see it in here – ring rust, everything. No excuses, though. He’s cut me across the eye there. It was a good, rough fight. Perfect.” Usyk, 36, then said: “Let’s go. I’m going to be fighting him, amazing. It’s a big fight, the whole world wants this fight. We’re back in this ring, 23 December, thank you very much, I go to sleep.” Fury said: “It’s been going on a long time, let’s do the fight – over here, for all the belts, the undisputed title of the world. Listen, it’s not up to me; we’d go now. These guys will sort it out, it’ll be my next fight guaranteed.” But Warren added: “I don’t think the date will be announced just yet. This fight is on. Both fighters want it. Tyson’s got a cut there. We’ll see how it heals. “It’s the biggest fight in boxing. Everybody wants to see it. They’ll see it in Saudi, it’ll break all box-office records.” Read More Fury vs Ngannou prize money: How much are fighters earning tonight? Cristiano Ronaldo ‘punches’ Tyson Fury as pair joke ahead of Francis Ngannou fight David Adeleye sparks outrage after punching referee on Fury v Ngannou undercard Tyson Fury and Oleksandr Usyk confirm date for heavyweight unification fight David Adeleye punches referee on Fury v Ngannou undercard Fury vs Ngannou stream fails as fans left with screeching sound

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