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The market for environmental, social and corporate governance, or ESG, investing is fundamentally broken.

Using existing drugs to treat cervical cancer before standard treatment could lead to a 35% reduction in the risk of relapse or death, a new study suggests. Researchers from the UCL Cancer Institute and UCLH looked into whether a short course of induction chemotherapy (IC), where a drug is used to destroy as many cancer cells as possible, before chemoradiation (CRT), could help with this. Here’s everything you need to know about the findings… What is cervical cancer? According to the NHS website, cervical cancer is a type of cancer found anywhere near the cervix – the opening between the vagina and the womb (uterus), which is also known as the neck of the womb. Most cervical cancers grow very slowly and are caused by an infection from specific types of human papillomavirus (HPV) and mostly affect women under the age of 45. According to Jo’s Cervical Cancer Trust, symptoms include vaginal bleeding that is unusual to you, changes to vaginal discharge, discomfort during sex and pain in your lower back or pelvis. Changes to cells can be spotted by a cervical screening, and then treated before they turn into cancer. There are around 3,200 new cases every year in the UK, with the five-year survival rate being around 70%, according to Cancer Research UK. CRT has been the standard treatment for cervical cancer patients since 1999, but even though there have been overall significant developments in radiation therapy techniques, up to 30% of people experience their cancer coming back. What did the research involve? Over a 10-year period, 500 patients who had been diagnosed with cervical cancer – that was large enough to see without a microscope but hadn’t spread to other parts of the body – took part in the Interlace trial at hospitals in the UK, Mexico, India, Italy and Brazil. Researchers looked into whether a short course of IC before CRT could reduce rates of relapse and death. What results were found? After five years, researchers discovered that 80% of the people who received a combination of chemotherapy and radiotherapy were alive, whilst 73% had not seen their cancer return or spread. A major benefit, according to researchers, is that it can be incorporated into standard of care treatment relatively quickly, because cheap, accessible and already-approved ingredients such as carboplatin and paclitaxel are needed for IC. “Our trial shows that this short course of additional chemotherapy delivered immediately before the standard CRT can reduce the risk of the cancer returning or death by 35%,” said Dr Mary McCormack, lead investigator of the trial from UCL Cancer Institute and UCLH. “This is the biggest improvement in outcome in this disease in over 20 years. “I’m incredibly proud of all the patients who participated in the trial; their contribution has allowed us to gather the evidence needed to improve treatment of cervical cancer patients everywhere. “We couldn’t have done this without the generous support of Cancer Research UK.” Why is the research important? Dr Iain Foulkes, executive director of research and innovation at Cancer Research UK, said: “Timing is everything when you’re treating cancer. The simple act of adding induction chemotherapy to the start of chemoradiation treatment for cervical cancer has delivered remarkable results in this trial. “A growing body of evidence is showing the value of additional rounds of chemotherapy before other treatments like surgery and radiotherapy in several other cancers. “Not only can it reduce the chances of cancer coming back, it can be delivered quickly using drugs already available worldwide. “We’re excited for the improvements this trial could bring to cervical cancer treatment and hope short courses of induction chemotherapy will be rapidly adopted in the clinic.”

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Mark Barlet founded AbleGamers in 2004

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ANKARA Turkey sent two cargo planes to Egypt on Monday carrying medical equipment and supplies for Gaza, Health

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With the weekend’s action wrapped, Fantasy Premier League managers will be reflecting upon another week of either frustration or elation after some dramatic late finishes and plenty of eye-catching performances. As the Premier League enters its 10th week, FPL managers may be looking to ring the changes as fixture swings occur and new in-form teams emerge. Whether you are looking to just tinker with one or two changes or are planning a number of wholesale changes, here are five players we think you should keep an eye out for ahead of gameweek 10. Phil Foden - Manchester City, midfield (7.6 m) The Manchester City winger has often been an unreliable FPL asset due to his lack of regular starts. Riyad Mahrez’s departure for the Saudi Pro League has now cleared the way for Foden who has started all but one of City’s league games this season. Returns thus far haven’t been plentiful (1G, 3A) and his ownership has dropped as a result, but after a promising display for England in the international break and a much-needed win for City against Brighton at the weekend, the 23-year-old may offer something of a differential pick if you’re looking to make up some ground on mini-league rivals. Kieran Trippier - Newcastle, defender (6.9 m) After a tough run of fixtures at the start of the season, Newcastle are unbeaten in five and back in full flow. Trippier has been the fulcrum of their recent improved performances, with his six assists in his last four games seeing him rise to the top of the points list for defenders. A trickier set of fixtures are on the horizon, but with games against Wolves and Bournemouth mixed in, the experienced right-back should be at the forefront of many people’s plans if they are looking for a premium defensive asset. Alisson - Liverpool, goalkeeper (5.5 m) Going big on keepers is not something many FPL managers see as a necessity but with Liverpool’s good run of fixtures coming up, spending that little bit more to bring in Alisson could be a rewarding transfer. Jurgen Klopp’s side restricted Everton to just 0.09 xG in their 2-0 derby win on Saturday and have fixtures against Nottingham Forest, Luton Town and Fulham in their next five. Ezri Konsa - Aston Villa, defeder (4.5 m) Aston Villa’s statement 4-1 win over West Ham on Sunday continued their superb start to the season as they extended their unbeaten run to six games and remain just one point off the top four. Defensively, they were a tad unfortunate to not keep a clean sheet, with Jarrod Bowen’s heavily deflected strike somehow finding the bottom corner from long range. With fixtures against Luton, Forest and Fulham in their next three, defensive returns are a high likelihood and Ezri Konsa looks to offer some value at just 4.5m. The centre-back picked up an assist against the Hammers and also has two bonus points in his last four games. Neal Maupay - Brentford, forward (4.9 m) There was a time not too long ago when few, if any, FPL users would have looked at Maupay with a transfer in mind. But fresh off an assist in his first start back at Brentford, the Frenchman could be a player rejuvenated. It remains early days but as a potential rotation option, Maupay could offer something different if you are looking to make room for a more expensive player elsewhere. Read More FPL GW9: Watkins, Gordon and five players to consider for transfers Sir Bobby Charlton: England’s greatest ever player and the artist of 1966 Man Utd expect to pay further tribute to Sir Bobby Charlton on Tuesday night Sir Bobby Charlton: England’s greatest ever player and the artist of 1966 Man Utd expect to pay further tribute to Sir Bobby Charlton on Tuesday night Virgil van Dijk will show he is Premier League’s best once more – Sami Hyypia

One of the world's finest spin bowlers, Bishan Bedi took 1,560 first-class wickets, the highest by an Indian.

A man lit a small fire to heat up his coffee kettle. It was a hot and windy