List of All Articles with Tag 'al'

There are more than 47,000 men diagnosed with prostate cancer every year in England but new research says using MRI scans can reduce deaths caused by the disease. Current tests usually detect the level of the protein prostate-specific antigen (PSA) in the blood, but scientists say this has meant overdiagnosis and overtreatment of low-risk cancer. The Reimagine study, by University College London, University College London Hospitals NHS Foundation Trust and King’s College London, invited 303 men aged between 50 and 75 to have a screening MRI and a PSA test. Of those men, 48 (16%) had an MRI that indicated prostate cancer despite having a median PSA density – 32 of those had lower PSA levels than the current screening benchmark, meaning they would ordinarily not have been referred for investigation. After NHS assessment 29 were diagnosed with cancer that required treatment, and three were diagnosed with low-risk cancer with no need for treatment. Prof Caroline Moore, consultant surgeon at UCLH, chief investigator of the study and NIHR research professor, called the findings “sobering”. She said: “Our results give an early indication that MRI could offer a more reliable method of detecting potentially serious cancers early, with the added benefit that less than 1% of participants were ‘over-diagnosed’ with low-risk disease.” What is prostate cancer? Prostate cancer is the UK’s most common male cancer. It affects the prostate – a walnut-sized gland that sits beneath the bladder and surrounds the urethra in people born with male sex organs. Its main purpose is to help produce semen (the fluid that carries sperm). Prostate cancer can develop when cells in the prostate start to grow in an uncontrolled way. While some prostate cancers grow quickly and spread, others grow too slowly to cause any problems and therefore will never need any treatment. What are the risk factors “Prostate cancer is a disease we tend to see in older age groups (over-50s), but there are exceptions, as with any form of cancer,” said Dr Sanjay Mehta, GP at The London General Practice. According to Prostate Cancer UK black men are at a higher risk – one in four black men will get prostate cancer in their lifetime (compared to one in eight for other men). The risk increases after the age of 45. Family history is important too; your father or brother has had prostate cancer or your mother or sister has had breast cancer, your risk is higher. What are the symptoms? Often there aren’t any signs in the early stages, so be aware of your own risk factors and chat to your doctor if concerned. Prostate Cancer UK have an online risk checker you can use too. Mehta said to watch out for urinary symptoms and changes to how you urinate. “So frequency, where you need to go more often. Hesitancy, where you’re standing over the toilet bowl and a period of time will pass before you’re able to pass urine, and ‘dribbling’, where you’ve finished but find you’re still passing when you walk away. “These are common in older men anyway. But if it’s new for you, and you find you’re having to go more often at night, and you’re having hesitancy or urgency, see your doctor.” Other things to get checked include erectile dysfunction, blood in your urine, and any new and unexplained lower back pain. “Then there are general systemic symptoms, like lethargy, lack of appetite,” added Mehta. “Again, these things often happen anyway, but if it’s a change for you and it’s been happening for a couple of weeks, see your doctor.” How is prostate cancer diagnosed and treated? First, your doctor will chat through your symptoms and history with you. “The next step would involve an examination, including a rectal examination of the prostate,” said Mehta, before referral for further investigations. “I appreciate this can put some men off seeing their doctor but it is a very helpful way of assessing things”. After diagnosis, treatment depends on the stage of the cancer and what’s suitable for each individual, but it may include surgery or radiotherapy. Caught early, prostate cancer is generally very treatable. And even with advanced prostate cancer, treatments have come a long way. Read More Charity boss speaks out over ‘traumatic’ encounter with royal aide Ukraine war’s heaviest fight rages in east - follow live Keep fit to avoid heart rhythm disorder and stroke, study suggests How to give your home a proper summer sort out What you really need to do in autumn to keep your lawn in shape

Even after a record slump that wiped out €21 billion ($23 billion) in value, some investors think Adyen

Keke Palmer has heaped praise on Sergio Hudson, explaining that his designs help to "accentuate" her figure.

The Lionesses have landed back in the UK after their World Cup final defeat as fans gathered at the airport in the hopes of welcoming them home. Around 40 people brought England flags and handmade banners to Heathrow Airport on Tuesday morning, with one group having arrived on Monday night, but the team are understood to have left via a private exit after touching down just after 6.30am. Others brought flowers for head coach Sarina Wiegman, while placards featured messages saying, ‘You all made us proud,’ and ‘Can we have two T-shirts please?’ Hopes were raised when former England player and presenter Alex Scott was spotted walking through arrivals, with fans saying she hinted the team would follow, and the crowd burst out into chants of “Sweet Caroline”. The team’s bags with the squad logo were also carried through. Hope turned to disappointment when it was later confirmed by airport staff that the Lionesses had left the airport and the crowd soon dispersed. A small number of fans watched at arrivals for a little longer just to be sure they had not missed out on any action. Joanne Bruce, 51, travelled from Wisbech in Cambridgeshire to the airport at 10.30pm on Monday with her niece and sister in the hope of thanking the team for their tournament performance. She told the PA news agency: “We haven’t slept, we have just laughed and joked. It was just the three of us to start with. My sister was like, ‘I really want to go early’.” When asked if there any other fans were at the airport then she replied: “No, no, no. They didn’t come until about four o’clock this morning. We have now got a car parking ticket of £70-80, maybe more. “I was very, very disappointed [about the final result]. Seeing Millie [Bright, captain] with tears in her eyes, it just brought tears to my eyes. I really felt for them as well. “They have definitely done us proud, to get as far as they have.” Read More Pubs call for rule change after Lionesses fans made to wait until half-time for beer England’s impact will last far longer than pain of World Cup final defeat The bitter aftertaste of that unwanted World Cup kiss on the lips

A look at the day ahead in U.S. and global markets from Mike Dolan After a stifling August so far,

Lewis Hall has joined Newcastle on a season-long loan from Chelsea with the option for a permanent deal for the defender. The clubs have been in negotiations over a move for the 18-year-old academy graduate since last week, with Eddie Howe’s side having come in with an initial offer of £28million. The PA news agency understands that should Newcastle choose to make the deal permanent in a year’s time, the deal will include an additional £7m in possible add-ons plus a sell-on fee owed to Chelsea should he later depart. Hall agreed a new six-year contract to stay at Stamford Bridge earlier in August but Newcastle’s interest has persuaded the Blues to part company with a player who made 11 first-team appearances last season, including nine in the Premier League. In a difficult season for the club, the teenager’s integration into the senior set-up was one of a few bright spots, with one of his most impressive performances coming against his new side in a 1-1 draw on the last day of the season. His first start had come in a 1-0 defeat at St James’ Park in November, playing 73 minutes before being substituted, and after impressing interim boss Frank Lampard he went on to start in each of Chelsea’s final four games of the season. He first joined the club aged eight and progressed through the academy set-up before making his first-team debut under former manager Thomas Tuchel in a 5-1 win against Chesterfield in the FA Cup third round in January 2022 aged just 17, making him the youngest player to appear for the club in the competition. During Chelsea’s injury crisis that struck immediately following last year’s World Cup he was pressed into action as an emergency midfielder, enduring a difficult game as the team were dumped out of the FA Cup 4-0 by Manchester City in January. He becomes Newcastle’s fifth singing of the season as they prepare to make their first appearance in the Champions League since 2003. Read More Charity boss speaks out over ‘traumatic’ encounter with royal aide Ukraine war’s heaviest fight rages in east - follow live

A conspiracy theorist who last week claimed the end of the world was coming, issued an “explanation” as to why the Earth was not destroyed. Mike Buckner, an American conspiracy theorist, warned people that a rogue planet named Nibiru was going to strike on Friday 18 August, ending life on Earth as we know it. Buckner told users on X (formerly Twitter) that he was “heading for the caves” for his best chance of life after claiming “few will survive”. He wrote: “THE FINAL 24 HOURS OF CIVILIZATION NIBIRU APPROACHES. THE POLE SHIFT IS COMING. FLOODS. QUAKES. FIRES. “HEAD FOR SHELTER. CAVES. BUNKERS. ALERT YOUR FAMILY. FRIENDS. NEIGHBORS. FEW WILL SURVIVE. “I AM HEADED FOR THE CAVES. GOOD LUCK” As other users mentioned in the community notes on the post, “The world did not end” on Friday. But, according to Bucker, there is an explanation as to why the planet did not end in a fiery collision. Bucker explained the reason is because he now believes the Earth is flat. He doubled down on his rather bizarre prediction by completely changing his view on the shape of the planet. He wrote: “I thought I was right. I thought Nibiru was coming. The physics worked. What didn’t work was my fundamental understanding of reality. “I now know the Truth. We live on a flat plane. We live underneath a firmament. The Globalists lie for control. More to come.” In the past, NASA has previously commented on the fact that a planet called Nibiru does not exist. The same conspiracy theory that Earth was going to be struck by “Nibiru” arose twice in 2012, leading the space agency to set the record straight. The space agency said: “Nibiru and other stories about wayward planets are an Internet hoax. There is no factual basis for these claims. “If Nibiru or Planet X were real and headed for an encounter with the Earth...astronomers would have been tracking it for at least the past decade, and it would be visible by now to the naked eye. Obviously, it does not exist.” Sign up to our free Indy100 weekly newsletter Have your say in our news democracy. Click the upvote icon at the top of the page to help raise this article through the indy100 rankings.

Some three months after an election that represented one of the biggest challenges in years to Thailand’s royal

'Flip or Flop' star Tarek el Moussa acknowledges the importance of lessons learned in life on his 42nd birthday

Claims for weather-related incidents are set to exceed $100 billion for the third year in a row, as

iShowSpeed lived a fever dream in real life recently after accidentally exposing himself to thousands of fans, and it’s safe to say the internet isn’t letting him live it down. The 18-year-old was live streaming to 24,000 fans when the incident took place and he inadvertently flashed the camera, before immediately ending his stream with a look of panic on his face. He escaped being banned by YouTube, but since then, he’s been subjected to trolling by fans – and he recently took issue with people “reposting” the clip and laughing at his expense. It’s clearly getting to iShowSpeed. One stream filmed since the incident shows his frustrations, standing up and screaming at the camera: “Like bro, how the f*** would you f***ing feel motherf***er? How the f*** would you feel?” “How would you feel? Just because you didn’t have any clean f***ing underwear? You had no clean underwear so you put on some goddamn pants! How would you feel?!” Showing how much the constant messages and trolling had impacted him he added: “I’m sick of f***ing chilling! You can’t chill! Don’t tell me to calm down.” It’s been clearly evident in the days since that he’s been suffering. The streamer also spoke about the "embarrassing moment," and how it's impacted him mentally. He begged his viewers to stop trolling him over the incident during his first stream back, but people still constantly calling him "IShowMeat" and flooding the chat with steak emojis and other comments. The impact of something like this is impossible to comprehend – especially for most of us whose life hasn’t been lived out with millions watching. The cruelty of the internet has always been evident in his streams. Even with the outpouring of support from fans in Japan, which saw them show up outside the building in Tokyo to show their support, thousands unsubscribed just at the moment he was due to hit 19 million subscribers, even when he’d “nearly died” just days before and was suffering with horrendous cluster headaches. The idea of having the worst moment of a person’s life at a young age broadcast to millions is the stuff of nightmares. Everyone knows how awful discourse online can be, with millions seemingly unable to respond with any degree of empathy to major events, and it’s no surprise to see social media users respond in such a way. "These past days and hours, I've been suffering very mentally, genuinely," iShowSpeed told viewers recently, honestly discussing his feelings since the incident. "At the end of the day, I'm still a human being." He said it was "one of the worst fears" that has happened and that it's "just depressing." "You guys are joking, you guys can crack your jokes – but you're genuinely not looking at the bigger picture," he said. "Do you all know I have family, little siblings?" "I don't know what to do anymore, bro," Speed added. As another TikToker pointed out, even his dad repeated the words “ishowmeat” in a recent stream, which has been used to refer to the incident. While it’s not clear whether or not Darren Watkins Sr knows of the relevance of his words, the fact others are asking him to say it and perpetuate it on his own stream speaks volumes. @noahglenncarter People are upset with IshowSpeed’s dad for saying this #foryou #ishowspeed #live Due to the permanence of the internet it’ll never go away completely, but we can only hope that things can move on for iShowSpeed soon. Thankfully, many have shown him support in the comments section. “Remember speed always make people laugh don't let him be sad. Stay Strong speed,” one said. Another wrote: “Its okay speed! People wont understand what you feel! I hope you get over this soon!” One more added: "Don't beat yourself up about it bro, we all make mistakes it'll pass and be forgotten, here for chats anytime, I didn't see the live and plan to avoid seeing any reposts. everyone should take a second and have some tact he's only 18 where I'm from thats a teenager." We hope these are the sorts of comments iShowSpeed sees more of over the coming days. Sign up for our free Indy100 weekly newsletter Have your say in our news democracy. Click the upvote icon at the top of the page to help raise this article through the indy100 rankings.

Rangers and PSV meet for a second year in succession with a place in the Champions League group stages on the line. The two-legged play-off encounter will determine which club is in the draw for the tournament proper on Thursday 31 August. It was the Scottish side that progressed from this stage in 2022 with a narrow away victory, but Michael Beale’s side have endured a mixed start to the new season. PSV, meanwhile, looked in good form in dispatching SK Sturm Graz by a 7-2 aggregate scoreline in the third qualifying round. Here’s everything you need to know. When is Rangers vs PSV? The first leg of the Champions League play-off between Rangers and PSV is due to kick off at 8pm BST on Tuesday 22 August at Ibrox in Glasgow. How can I watch it? Viewers in the United Kingdom can watch the match live on TNT Sports 1, with coverage on the channel from 7.30pm BST. Subscribers can stream the action via discovery+, the streaming home of the rebranded TNT Sports. Team news Ianis Hagi and Ridvan Yilmaz have been omitted from the Rangers squad, with the former potentially moving closer to an exit from the club. James Tavernier and Todd Cantwell were among those not involved in the cup win over Greenock Morton, but should return for the first leg. Phillipp Mwene and Patrick van Aanholt have remained in the Netherlands due to injuries, leaving Peter Bosz with a slight problem at left back. New signing Sergino Dest is available after his loan move from Barcelona went through on Monday, but this first leg may come too soon for a full debut. Predicted line-ups Rangers XI: Butland; Tavernier, Goldson, Souttar, Barisic; Cifuentes, Cantwell, Jack, l; Sima, Danilo, Dessers. PSV Eindhoven: Benitez; Teze, Ramalho, Boscagli, Sambo; Veerman, Sangare; Bakayoko, Til, Vertessen; De Jong. Odds Rangers win 2/1 Draw 13/5 PSV win 7/5 Prediction A score draw leaves things in the balance ahead of next week’s second leg. Rangers 2-2 PSV Read More England’s impact will last far longer than pain of World Cup final defeat Everton condemn ‘vile’ racist abuse aimed at midfielder Amadou Onana Mason Greenwood will not play for Manchester United again, club announce