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An effective and massively popular weight-loss drug has made Novo Nordisk A/S billions of dollars and turned it

Mikel Arteta is hopeful Bukayo Saka will be fine after the Arsenal forward was brought off with a “knock’’ in the Champions League victory over Sevilla. Saka was the star of the show as Arsenal brushed Sevilla aside in a 2-0 win at the Emirates, setting up Leandro Trossard’s opener before doubling the hosts’ lead in the second half. But the 22-year-old was once again on the receiving end of several fouls from the Sevilla defenders and signalled to come off late in the contest after an awkward landing. Arteta, however, did not appear to be overly concerned after Saka’s early exit. Arsenal host Burnley in the Premier League on Saturday, while Gareth Southgate watched on at the Emirates ahead of announcing his England squad on Thursday ahead of qualifiers against Malta and North Macedonia. Saka will be hoping to return to the England squad after missing October’s internationals and Arteta said: “It was just a kick and I was told by the physios he wasn’t happy to continue. I want to assume he will be OK.” Arteta said Saka is “getting used” to being on the receiving end of challenges after Sevilla fouled the winger four times inside the opening 20 minutes of the Group B fixture. “That’s not going to change,” Areta said. “The way he attacks players.” Arsenal were without captain Martin Odegaard and striker Eddie Nketiah against Sevilla, but Arteta said both are “racing against the clock” and could be fit for Saturday. Gabriel Jesus, who was also missing due to injury, will not be back until after the international break. Read More Bukayo Saka and Gabriel Martinelli dazzle to lead Arsenal towards last-16 Bukayo Saka does not fear burnout and is keen to feature in every Arsenal match Eddie Nketiah hits hat-trick as five-star Arsenal sweep aside Sheffield United

By Ted Hesson WASHINGTON A group of Democratic lawmakers on Wednesday urged U.S. President Joe Biden to allow

A majority of the human body is made up of water, which is why staying hydrated so important. It can be confusing to determine how much the average person should drink in a day, especially in situations like when it’s hot outside or when you’re exercising. There are even consequences to not drinking the right amount of water, such as dehydration or overhydration. The National Health Service (NHS) typically recommends drinking between six to eight glasses of fluid, including water, every day. But the US National Academies of Sciences, Engineering, and Medicine has determined that an adequate daily fluid intake is 15.5 cups (3.7 litres) per day for men and 11.5 cups (2.7 litres) per day for women. However, this fluid intake accounts for drinking plain water as well as other beverages and food that contain water, like fruits and vegetables. The amount of water one should be drinking each day can also vary depending on the situation. According to the Mayo Clinic, those who are working out should be drinking extra water before, during, and after a period of exercise. This especially goes for any activity that makes you sweat, because drinking water helps replenish the fluid your body lost. People in hot or humid weather should be drinking more water than usual because of how much they’re sweating, which contributes to fluid loss. Meanwhile, in areas with higher altitudes like the mountains, dehydration can become more common. The Mayo Clinic suggests that people lose bodily fluids when they have a fever, are vomiting, or have diarrhoea. As such, it’s important that people are consuming extra water when they’re sick. Other conditions that might require increased fluid intake include bladder infections and urinary tract stones. Feeling thirsty and passing dark-coloured, strong-smelling urine are some of the initial signs that you could be dehydrated. Other symptoms include feeling sluggish, feeling light headed, or having a dry mouth. Drinking milk, water, and fruit juice is also a good way to maintain hydration. However, people should bear in mind the amount of sugar that can be contained in sweetened drinks. Tea and coffee may also help with hydration, though people should try to keep track of how much caffeine they’re consuming. While it’s important to know whether you’re drinking enough water, the Mayo Clinic suggests it’s likely that nothing is wrong with someone’s water intake if they rarely feel thirsty and their urine is clear, or a light yellow colour. It is possible to drink too much, however, it’s rarely a problem for someone with healthy kidneys. Still, overhydration can occur when the body retains or collects too much water. Some athletes who participate in endurance events, especially marathon runners, can be prone to taking on too much fluid. This can lead to water intoxication and dangerously low sodium levels, which is referred to as hyponatraemia. In order to help the body to relieve itself of excess water, as well as relieve pressure on the heart and other organs, doctors may prescribe diuretics or water tablets that promote the production of urine. Read More Irina Shayk reveals how she and Bradley Cooper make co-parenting daughter Lea ‘work’ What is silent reflux? Salon owner with incurable cancer who lost hair in treatment makes customisable wigs

Stocks in Asia were primed to advance after US shares hit their hottest winning streak in two years,

Bill Holdings Inc. is in advanced talks to acquire Melio Payments, a provider of digital payment tools, people

The Minnesota Supreme Court dismissed an effort to disqualify Donald Trump from appearing on ballots in the state’s

Match reaction and player ratings from Real Madrid vs Braga in the Champions League on Wednesday evening.

Instagram is testing a new feature that turns off read receipts for direct messages. "You

Arsenal took a huge step towards qualifying for the knock-out stages of the Champions League as Bukayo Saka starred in victory over Sevilla before limping off late on. Saka set up the opening goal for Leandro Trossard before scoring the second himself as the Gunners secured a straightforward 2-0 win at the Emirates Stadium that leaves them on the cusp of the last 16. Mikel Arteta opted to play Trossard through the middle as his central striker with Eddie Nketiah joining Gabriel Jesus in the treatment room, with the Belgium forward the only change from Saturday’s contentious defeat at Newcastle. There was not such drama here although four early fouls on Saka went unpunished as both Nemanja Gudelj and Kike Salas left their mark on the England international. Kai Havertz, without a goal from open play since his £65million summer move from Chelsea, fluffed his lines with an early headed chance, but Arsenal set out their intent from the off. Saka went down again under close contact from Salas, but this time Romanian referee Istvan Kovacs was unmoved as the hosts wanted a penalty. Just moments later, however, and the deadlock was broken. The lively Saka unsurprisingly laying on the assist for Trossard to tap home – but Jorginho was the architect with a slide-rule pass to start the move. It proved to be the only shot on target of a forgettable first half as Sevilla, without a LaLiga or Champions League win under head coach Diego Alonso since his appointment last month. Havertz bent an effort inches wide as Arsenal went in search of a second after the break and Trossard should have done better soon after, but curled his strike the wrong side of the post. It was Saka, though, who made the difference once again, beating the offside trap to race onto a Gabriel Martinelli pass before cutting inside Adria Pedrosa and tucking home with aplomb. Gabriel Jesus had provided the goal and assist that ultimately saw off Sevilla in Spain a fortnight ago, but he was injured during the game and has not played since. The same went for Saka here, who fell awkwardly and limped off with five minutes to go, with England manager Gareth Southgate – who announces his next squad on Thursday – watching from the stands. Arteta had said on the eve of the game that Arsenal should “put to bed” qualification for the last 16 with two games to spare and his players did their bit. But PSV Eindhoven’s win over Lens leaves Group B open, although a draw against the Ligue 1 side at the Emirates Stadium in three weeks time would be enough for Arteta’s side to advance. Read More Jarell Quansah could fill in for Liverpool captain Virgil van Dijk in Toulouse Gareth Southgate ponders defensive options ahead of naming latest England squad Jos Buttler wants to remain as England one-day captain despite poor World Cup Lauren Williams opens up on challenging time coping with Tokyo heartbreak Michael O’Neill expecting a tough international window for Northern Ireland Sunderland defender Niall Huggins earns first senior Wales call-up

Instacart reported better-than-expected earnings in the third quarter, showing modest growth in online grocery orders and assuaging some

Starting next year, Facebook and Instagram will require political ad campaigns to disclose if they