Irish woman found dead after shooting in New York
A man and a woman in their 30s were found with gunshot wounds to their heads in Queens area of New York.
2023-10-23 21:17
5 breakout fantasy football stars to pick up for Week 8
Three running backs headline the top fantasy football pickups to make ahead of Week 8.
2023-10-23 20:58
EuroLeague Week 3 Winners and Losers: Undefeated Real Madrid, Fenerbahce's resilience, and Monaco fights back
Week 3 of EuroLeague action brought the first double-game week and helped give some more space in the standings. Here’s a breakdown of week three’s winners and losers.
2023-10-23 20:46
What you need to know about new research into treating cervical cancer
Using existing drugs to treat cervical cancer before standard treatment could lead to a 35% reduction in the risk of relapse or death, a new study suggests. Researchers from the UCL Cancer Institute and UCLH looked into whether a short course of induction chemotherapy (IC), where a drug is used to destroy as many cancer cells as possible, before chemoradiation (CRT), could help with this. Here’s everything you need to know about the findings… What is cervical cancer? According to the NHS website, cervical cancer is a type of cancer found anywhere near the cervix – the opening between the vagina and the womb (uterus), which is also known as the neck of the womb. Most cervical cancers grow very slowly and are caused by an infection from specific types of human papillomavirus (HPV) and mostly affect women under the age of 45. According to Jo’s Cervical Cancer Trust, symptoms include vaginal bleeding that is unusual to you, changes to vaginal discharge, discomfort during sex and pain in your lower back or pelvis. Changes to cells can be spotted by a cervical screening, and then treated before they turn into cancer. There are around 3,200 new cases every year in the UK, with the five-year survival rate being around 70%, according to Cancer Research UK. CRT has been the standard treatment for cervical cancer patients since 1999, but even though there have been overall significant developments in radiation therapy techniques, up to 30% of people experience their cancer coming back. What did the research involve? Over a 10-year period, 500 patients who had been diagnosed with cervical cancer – that was large enough to see without a microscope but hadn’t spread to other parts of the body – took part in the Interlace trial at hospitals in the UK, Mexico, India, Italy and Brazil. Researchers looked into whether a short course of IC before CRT could reduce rates of relapse and death. What results were found? After five years, researchers discovered that 80% of the people who received a combination of chemotherapy and radiotherapy were alive, whilst 73% had not seen their cancer return or spread. A major benefit, according to researchers, is that it can be incorporated into standard of care treatment relatively quickly, because cheap, accessible and already-approved ingredients such as carboplatin and paclitaxel are needed for IC. “Our trial shows that this short course of additional chemotherapy delivered immediately before the standard CRT can reduce the risk of the cancer returning or death by 35%,” said Dr Mary McCormack, lead investigator of the trial from UCL Cancer Institute and UCLH. “This is the biggest improvement in outcome in this disease in over 20 years. “I’m incredibly proud of all the patients who participated in the trial; their contribution has allowed us to gather the evidence needed to improve treatment of cervical cancer patients everywhere. “We couldn’t have done this without the generous support of Cancer Research UK.” Why is the research important? Dr Iain Foulkes, executive director of research and innovation at Cancer Research UK, said: “Timing is everything when you’re treating cancer. The simple act of adding induction chemotherapy to the start of chemoradiation treatment for cervical cancer has delivered remarkable results in this trial. “A growing body of evidence is showing the value of additional rounds of chemotherapy before other treatments like surgery and radiotherapy in several other cancers. “Not only can it reduce the chances of cancer coming back, it can be delivered quickly using drugs already available worldwide. “We’re excited for the improvements this trial could bring to cervical cancer treatment and hope short courses of induction chemotherapy will be rapidly adopted in the clinic.”
2023-10-23 20:22
Israel's criticism of Irish president 'unhelpful'
The Israeli ambassador has accused the Irish president of making misinformed comments on the Israel-Gaza war.
2023-10-23 20:22
Final Fantasy 14 director eyes Diablo crossover, admits 'It's a tricky one'
Naoki Yoshida admits that whilst it's on his wish list for collaborations, it won't be easy.
2023-10-23 20:22
Offset: Confidence is the sexiest thing Cardi B can wear
Rapper Offset says it was Cardi B's confidence that won him over.
2023-10-23 19:54
Skulls and flowers on parade at Mexico's Catrinas procession
Mexicans dressed as skeletons parade through the streets of the capital ahead of the Day of the Dead.
2023-10-23 19:45
Roundup: Kendall Jenner, Bad Bunny Go to SNL After-Party; Bill Belichick Gets 300th Win; ALCS Headed to Game 7
Kendall Jenner joined Bad Bunny at the SNL after-party, Bill Belichick got his 300th win, the ALCS is headed for Game 7 and more in the Roundup.
2023-10-23 19:28
Bank of Canada to leave rates on hold as economy stalls, analysts say
By Steve Scherer OTTAWA The Bank of Canada (BoC) will leave interest rates on hold on Wednesday as
2023-10-23 18:28
11 Infamous '90s School Bans
From slap bracelets to finger-sized skateboards, these are the distractions that filled teachers' desk drawers in the '90s.
2023-10-23 18:28
Naomi Osaka opens up about fighting thoughts that she ‘won’t be a good mom’
Naomi Osaka has reflected on battling self-doubt and difficult thoughts as a new mother. The four-time Grand Slam tennis champion gave birth to her first child, a daughter named Shai, in July 2023. She shares Shai with her partner, rapper Cordae. On Sunday (22 October), Osaka shared some insights into her personal life with her fans to mark turning 26 earlier in the week. In an extended post on X, formerly Twitter, the Japanese athlete wrote about taking stock of her life so far, and wondering whether or not she’s taken the “correct path”. “I often try to retrace my steps to figure out how did I end up here,” she explained. “I know I say this often but I truly still feel like that kid playing on public courts in Queens, NY. “Randomly I wonder if I’m doing OK, is there a correct path to take in life or have I veered off onto the scenic route for a little bit? However, I’ve now come into the mindset that I can only keep moving forward and everything that will be, will be.” Osaka then shared her specific feelings of worry about her capabilities as a parent. “Something I had to conquer recently is fighting the thought that I won’t be a good mom,” she wrote. “So many doubts raced through my head I had to swat them away like mosquitoes. “Looking into Shai’s eyes and holding her I always think, ‘Wow this little person depends on me so much, I have to do better.’ It’s such a strange feeling watching your kid grow, you blink and they’re double the size in a few months. “Gratefulness reminds me to breathe and take in the little things (and the big ones).” Osaka ended her post by expressing her gratitude for having “another year” and for the people who support her. Osaka’s last competitive match was at the Toray Pan Pacific Open in September 2022, before she withdrew from the tournament due to abdominal pain. She announced her pregnancy in January 2023 shortly after stating that she wouldn’t be competing in the Australian Open later that month. Last month, Osaka spoke about her year away from playing tennis and mentioned how other female tennis stars’ longevity has influenced her desire to keep competing. “The whole process, it felt long and short at the same time,” she told the American sports news channel ESPN. “When I stepped away, it was Tokyo, that was the last tournament I played. I just remember watching the Australian Open and being very devastated, because I’ve never missed an Australian Open. “When I was watching Serena and Venus [Williams], I was thinking, ‘Ah, I probably no way will ever play at their age’, but sitting here, I’m like, ‘You know what? I might do that actually.’” Read More ‘Truly heartbroken’ Rebecca Adlington reveals late miscarriage Should we stop putting the clocks back? What the experts think ‘I lost over a stone on Ozempic, but now it’s run out what am I to do?’ ‘Truly heartbroken’ Rebecca Adlington reveals late miscarriage Should we stop putting the clocks back? What the experts think ‘I lost over a stone on Ozempic, but now it’s run out what am I to do?’
2023-10-23 17:29