List of All Articles with Tag 'ea'

Three Southwest states announced Monday they have struck a historic deal to cut millions of gallons of Colorado River water usage over the next four years, about half of which would be completed by next year, in an effort to stave off a crisis at the nation's largest reservoirs.

Replacements for Joe Mazzulla after the Celtics' embarrassing playoff performances.

A prosecutor in Germany has indicted former executives of surveillance technology company FinFisher GmbH, accusing them of unlawfully

Valencia have condemn fans' racist abuse of Vinicius Junior during Sunday's clash with Real Madrid.

Provides an overview of Ireland, including key dates and facts about this west European country.

If you’re not sure whether you want to spend your summer exploring the coast of California or making your way through the Mediterranean, the new Mango x Simon Miller collaboration is here to provide the warm-weather wardrobe of your dreams no matter where your vacation takes you.

Today's USMNT news includes rumors of West McKennie's next club, ChristianPulisic was pictured with the World No. 1 chessplayer and Zack Steffen has been linked with a transfer to Germany. USMNT news: Weston McKennie's next moveWeston McKennie assistedRodrigo's goal with a lo...

Man City could become the tenth team in history to win a treble, but what is the achievement and how could they accomplish it?

Previewing Brighton vs Man City in the Premier League, with TV & live stream details, team news, predicted lineups & score prediction.

Chelsea will be without one key player when Mauricio Pochettino joins the club.

The menopause treatment fezolinetant has been predicted as a “gamechanger” by experts for thousands of women who suffer from hot flushes. The drug, which is the first non-hormonal menopause treatment, was recently approved by America’s FDA. Experts are predicting it could be transformative for women for whom hormone replacement drugs (HRT) are not suitable. The drug was licensed in the US on 12 May and could be approved for use in the UK by the end of the year. According to a British Menopause Society survey, 79 per cent of women aged 45 to 65 experienced hot flushes as a result of their menopause transition, while 10 to 20 per cent describe the hot flushes as “near intolerable”. Here’s everything you need to know about fezolinetant: What is it used to treat? It works to target the menopause symptom of hot flushes. The drug that has been approved by the FDA is made by pharmaceutical company Astella, which advises patients to take one 45-milligram of its VEZOAH (fezolinetant) pill orally, once a day. A large clinical trial of fezolinetant published earlier this year revealed that, after 12 weeks of use, it reduced the frequency of hot flushes by about 60 per cent in women with moderate or severe symptoms, in comparison to a 45 per cent reduction in those who received a placebo. Women involved in the trial also said the drug reduced the severity of hot flushes and improved the quality of their sleep. How does it work? It works by blocking a brain protein called neurokinin-3, which plays a unique role in regulating body temperature in menopausal women. Respondents of the trial have said that the effects of the drug was experienced after taking the first tablet. By comparison, HRT, taken to alleviate menopausal symptoms, replaces the oestrogen that you lose during the menopause transition, either alone or in combination with a progestogen What are the side effects? According to the FDA, the most common side effects are abdominal pain, diarrhoea, insomnia, back pain, hot flush and elevated hepatic transaminases. What have experts said about it? “This is going to be a completely blockbuster drug,” said Prof Waljit Dhillo, an endocrinologist at Imperial College London who led a trial for the drug in 2017 toldThe Guardian. “It’s like a switch. Within a day or two the flushes go away. It’s unbelievable how well these drugs work. It’s going to be completely game changing for a lot of women.” Read More Adenomyosis: 5 things you need to know about the ‘evil twin sister’ of endometriosis ‘Suddenly, I saw Dad again’: The radical technology helping those living with dementia Naga Munchetty reveals womb condition adenomyosis: ‘I live every day on painkillers’

Why be sweltering and sunburnt when you can be swoly and birsled instead?