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Women more severely affected by ME, study claims
Women more severely affected by ME, study claims
Women with myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) tend to have more symptoms and co-occurring conditions than men, according to the world’s largest study of the disease. The study, entitled DecodeME, reveals women who have the condition for more than 10 years are more likely to experience increasingly severe symptoms as they get older. ME/CFS is estimated to affect more than 250,000 people in the UK, of all ages and from all social and economic backgrounds. Its key feature, called post-exertional malaise, is a delayed dramatic worsening of symptoms following minor physical effort. Other symptoms include pain, brain fog and extreme energy limitation that does not improve with rest. Causes are unknown and there is currently no diagnostic test or cure. Experts from the University of Edinburgh analysed anonymous survey questionnaires from more than 17,000 people with ME/CFS. Two-thirds of women, and slightly more than half of men, reported at least one active co-occurring condition. Similarly, 39.2% of women and 28.6% of men reported at least one inactive co-occurring condition. We discovered that the disease is worse for women, in older people, and many years after their ME/CFS started Professor Chris Ponting of the University of Edinburgh A condition was considered active if the participant had experienced symptoms in the preceding six months. The most common active co-occurring condition was irritable bowel syndrome, with clinical depression, fibromyalgia, anaemia and hypothyroidism also featuring prominently. Women also reported, on average, more symptoms than men – 42 compared with 36. The most common of these symptoms were brain fog – a term commonly used to describe the cognitive impairment experienced by participants – unrefreshing sleep and muscle pain. These findings highlight the very serious impact ME/CFS has on women who are disproportionately affected Sonya Chowdhury, chief executive of Action for M.E Participants were also asked to define the severity of their illness from mild to very severe using definitions from the UK’s National Institute for Health and Care Excellence guidelines. Experts identified that being a woman and having ME/CFS for more than 10 years are risk factors for severe illness, with symptoms increasing in intensity as they age. Professor Chris Ponting, study lead from the MRC human genetics unit at the University of Edinburgh’s Institute of Genetics and Cancer, said: “ME/CFS is a devastating disease affecting a UK population the size of Derby. “We discovered that the disease is worse for women, in older people, and many years after their ME/CFS started. “Our hope is that DecodeME’s genetic results will shed light on why certain groups are more susceptible to ME/CFS than others.” Sonya Chowdhury, chief executive of Action for M.E. and chair of the management group of the study, said: “These findings highlight the very serious impact ME/CFS has on women who are disproportionately affected. “It’s important to also recognise the impact that it has on men who have ME/CFS and we thank the 20,000 men and women who have already signed up to take part in this very important study. “We still need more to join us, so if you are 16 or older, live in the UK and have a diagnosis of ME/CFS, please do take part now to help us decode ME at www.decodeme.org.uk/portal.” Read More Charity boss speaks out over ‘traumatic’ encounter with royal aide Ukraine war’s heaviest fight rages in east - follow live 4 hacks to get teens off the sofa and get active – as study warns of heart damage Taking adult education classes may lower risk of dementia, study suggests Indiyah Polack: I didn’t want to go on Love Island because of my acne
1970-01-01 08:00
Chandrayaan-3: India lunar rover Pragyaan takes a walk on the Moon
Chandrayaan-3: India lunar rover Pragyaan takes a walk on the Moon
Chandrayaan-3's rover Pragyaan exits Vikram lander and takes first steps near the little-explored south pole.
1970-01-01 08:00
Republican debate: Candidates brawl in showdown without Trump
Republican debate: Candidates brawl in showdown without Trump
The rivals clash over their readiness for the job, abortion, education - and the no-show frontrunner.
1970-01-01 08:00
Texas A&M fans all want seats to the Jimbo-Petrino three-ring circus
Texas A&M fans all want seats to the Jimbo-Petrino three-ring circus
As Texas A&M tries to rebuild from a terrible offensive 2022-23 campaign, the Aggies have been able to sell out their allotted season tickets. Does the 12th man believe in their new offense?
1970-01-01 08:00
Sinopec Said to Eye Shell’s Historic Singapore Oil Refinery
Sinopec Said to Eye Shell’s Historic Singapore Oil Refinery
China’s state-owned Sinopec is among several parties circling Shell Plc’s storied Bukom oil refinery in Singapore, an asset
1970-01-01 08:00
Yevgeny Prigozhin: Wagner challenged Putin and now its leader is dead
Yevgeny Prigozhin: Wagner challenged Putin and now its leader is dead
If Yevgeny Prigozhin's death is revenge, it sends a clear message to Russians, writes Steve Rosenberg.
1970-01-01 08:00
Key moments from Republican presidential debate so far
Key moments from Republican presidential debate so far
It was a race to see who out of eight candidates would make a splash during the first Republican debate.
1970-01-01 08:00
Fact check: The first Republican presidential debate of the 2024 election
Fact check: The first Republican presidential debate of the 2024 election
Eight candidates for the Republican nomination for president took the stage for the first GOP debate Wednesday night in Milwaukee. Below is a fact check of some of their statements.
1970-01-01 08:00
LG Chem seeks to sell IT film business to improve competitiveness
LG Chem seeks to sell IT film business to improve competitiveness
SEOUL South Korean petrochemicals maker LG Chem Ltd said on Thursday it is seeking to sell its information
1970-01-01 08:00
Former USC star Reggie Bush files defamation suit against NCAA, wants Heisman Trophy back
Former USC star Reggie Bush files defamation suit against NCAA, wants Heisman Trophy back
Former University of Southern California superstar Reggie Bush is accusing the NCAA of defamation in a lawsuit filed Wednesday in an Indiana Superior Court, and is again asking the collegiate sports governing body to reinstate his football records so he can get his 2005 Heisman Trophy back.
1970-01-01 08:00
Latest Shohei Ohtani update is horribly depressing for Angels
Latest Shohei Ohtani update is horribly depressing for Angels
Shohei Ohtani was removed from the mound in the second inning of the Los Angeles Angels' Wednesday afternoon loss due to another arm problem.
1970-01-01 08:00
Chiefs Rumors: Reid addresses Chris Jones, growing trade buzz, roster bubble
Chiefs Rumors: Reid addresses Chris Jones, growing trade buzz, roster bubble
In today's Chiefs rumors, Andy Reid gives an unsettling update on Chris Jones, Clyde Edwards-Helaire lands on the trading block, and a handful of roster bubble players meet their fates.
1970-01-01 08:00
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