List of All Articles with Tag 'hea'

NEW DELHI India will make tests mandatory for cough syrups before they are exported, a government notice showed

By Jennifer Rigby DUBLIN Weight loss drug Wegovy has transformed the obesity market and pharmaceutical companies with existing

Jimmy Butler is flaming the Boston Celtics on and off the court en route to the Miami Heat's 3-0 series lead.The Miami Heat entered the NBA playoffs as the No. 8 seed. They were a seemingly mediocre offensive team stewing in season-long turmoil. When the Hawks beat the Heat in the first pla...

Junior doctors in England will stage another 72-hour walkout over pay, as they warn of a summer of

Get ready for a long NBA layoff before the finals.

The Miami Heat and Denver Nuggets hold 3-0 leads in their respective NBA Conference Finals matchups, thanks to huge contributions from key role players.Superstars get the headlines in the NBA, especially in the conference finals. But with the Heat and Nuggets holding commanding 3-0 leads and the...

Carmelo Anthony officially retired, setting off a nonsensical Hall-of-Fame debate. Also, Duncan Robinson is knocking down 3s again as the Heat keep rolling.The five-year, $90 million contract Duncan Robinson signed after the 2020-21 season looked like an overpay at the time. In the nearly two ye...

By Tom Polansek WICHITA, Kansas Farmers in Kansas, the biggest U.S. producer of wheat used to make bread,

The Miami Heat are putting it to the Boston Celtics.As has been the way for the No. 8 seed all postseason, the Heat have looked like the better team despite being underdogs in each of the three series the team has played in, now up 3-0 on the No. 2 seed Celtics in the Eastern Conference Finals. ...

Dysfunctional waste-water treatment around the South African capital of Pretoria contributed to a deadly cholera outbreak that’s left

By Emma Farge GENEVA The head of the World Health Organization urged countries on Monday to carry out

The menopause treatment fezolinetant has been predicted as a “gamechanger” by experts for thousands of women who suffer from hot flushes. The drug, which is the first non-hormonal menopause treatment, was recently approved by America’s FDA. Experts are predicting it could be transformative for women for whom hormone replacement drugs (HRT) are not suitable. The drug was licensed in the US on 12 May and could be approved for use in the UK by the end of the year. According to a British Menopause Society survey, 79 per cent of women aged 45 to 65 experienced hot flushes as a result of their menopause transition, while 10 to 20 per cent describe the hot flushes as “near intolerable”. Here’s everything you need to know about fezolinetant: What is it used to treat? It works to target the menopause symptom of hot flushes. The drug that has been approved by the FDA is made by pharmaceutical company Astella, which advises patients to take one 45-milligram of its VEZOAH (fezolinetant) pill orally, once a day. A large clinical trial of fezolinetant published earlier this year revealed that, after 12 weeks of use, it reduced the frequency of hot flushes by about 60 per cent in women with moderate or severe symptoms, in comparison to a 45 per cent reduction in those who received a placebo. Women involved in the trial also said the drug reduced the severity of hot flushes and improved the quality of their sleep. How does it work? It works by blocking a brain protein called neurokinin-3, which plays a unique role in regulating body temperature in menopausal women. Respondents of the trial have said that the effects of the drug was experienced after taking the first tablet. By comparison, HRT, taken to alleviate menopausal symptoms, replaces the oestrogen that you lose during the menopause transition, either alone or in combination with a progestogen What are the side effects? According to the FDA, the most common side effects are abdominal pain, diarrhoea, insomnia, back pain, hot flush and elevated hepatic transaminases. What have experts said about it? “This is going to be a completely blockbuster drug,” said Prof Waljit Dhillo, an endocrinologist at Imperial College London who led a trial for the drug in 2017 toldThe Guardian. “It’s like a switch. Within a day or two the flushes go away. It’s unbelievable how well these drugs work. It’s going to be completely game changing for a lot of women.” Read More Adenomyosis: 5 things you need to know about the ‘evil twin sister’ of endometriosis ‘Suddenly, I saw Dad again’: The radical technology helping those living with dementia Naga Munchetty reveals womb condition adenomyosis: ‘I live every day on painkillers’