List of All Articles with Tag 'ie'

Britney Spears has detailed how her relationship with Justin Timberlake ended when the former NSYNC star dumped her via a text message. In her upcoming memoir The Woman in Me, the 41-year-old singer revealed how the "devastating" break-up of the three-year relationship back in 2002 impacted her. “I was comatose in Louisiana, and he was happily running around Hollywood,” she wrote in an excerpt as per the New York Times. Spears said the break-up affected her so much that she considered quitting the music industry at the time. After Timberlake released his "Cry Me a River” music video where it's believed to portray Spears, she commented on the women's likeness and noted how the video had "a woman who looks like me cheats on him and he wanders around sad in the rain." Following their split, the Baby One More Time singer noted the difference in how the media characterised her and Timberlake. She believed the media presented her as a "harlot who’d broken the heart of America’s golden boy," and expressed how she felt forced by her father and management to do the infamous Diane Sawyer interview where was quizzed on her former relationship. Meanwhile, Spears admitted in the new memoir that she was unfaithful during her relationship with Timberlake - claiming she "made out" with dancer Wade Robson at a bar one night. But the pop star also alleged that Timberlake also cheated on her during their time together, but didn't name who with. Another personal detail that Spears revealed was how she fell pregnant during her relationship with Timberlake and ended up getting an abortion in late 2000 after Timberlake said they were "too young" to be parents. The Woman in Me will be released on 24 October. Sign up to our free Indy100 weekly newsletter Have your say in our news democracy. Click the upvote icon at the top of the page to help raise this article through the indy100 rankings.

Indraprastha Gas Ltd., India’s largest city gas distributor by revenue, is heading for its worst day in more

Economists raised their US growth projections through early 2024 and trimmed recession odds to a one-year low as

By Leika Kihara TOKYO The Bank of Japan said on Friday it will debate the benefits and costs

Consistently sleeping less than five hours a night could increase the risk of depression, research suggests. Poor sleep has been considered a side-effect of mental ill health in the past, but the new study found that the link between sleep and mental illness is more complex. People with a stronger genetic predisposition to short sleep – less than five hours in a given night – were more likely to develop depressive symptoms over four to 12 years, the study led by UCL researchers found. But those with a greater genetic predisposition to depression were not more likely to have short sleep. Using genetic susceptibility to disease, we determined that sleep likely precedes depressive symptoms, rather than the inverse Lead author Odessa Hamilton The experts also found that the link was not exclusive to those who were genetically inclined towards sleeping for shorter periods, and people who regularly dozed for five hours or less – without the genetic association – were also more likely to have depression. Lead author Odessa Hamilton, UCL Institute of Epidemiology and Health Care, said: “We have this chicken or egg scenario between suboptimal sleep duration and depression, they frequently co-occur, but which comes first is largely unresolved. “Using genetic susceptibility to disease, we determined that sleep likely precedes depressive symptoms, rather than the inverse.” Researchers used genetic and health data from 7,146 people recruited by the English Longitudinal Study of Ageing (ELSA), with an average age of 65. Short and long sleep durations, along with depression, are major contributors to (the) public health burden that are highly heritable Senior author Dr Olesya Ajnakina Analysis of genetic and health data suggested that short sleep was associated with the start of depressive symptoms, like feeling sad or lonely. Senior author Dr Olesya Ajnakina, UCL Institute of Epidemiology and Health Care and the Institute of Psychiatry, Psychology and Neuroscience at King’s College London, said: “Short and long sleep durations, along with depression, are major contributors to (the) public health burden that are highly heritable. “Polygenic scores, indices of an individual’s genetic propensity for a trait, are thought to be key in beginning to understand the nature of sleep duration and depressive symptoms.” When looking at non-genetic associations between depressive symptoms and sleep duration, the researchers also found that people sleeping five hours or less were 2.5 times more likely to develop depressive symptoms. And people with signs of depression were a third more likely to suffer from short sleep. Suboptimal sleep and depression increase with age, and with the worldwide phenomenon of population ageing there is a growing need to better understand the mechanism connecting depression and a lack of sleep Professor Andrew Steptoe The study, published in Nature, Translational Psychiatry, also revealed a link between sleeping long and developing depressive symptoms. According to the findings, people who slept for more than nine hours were 1.5 times more likely to develop depressive symptoms than those who sleep an average of seven hours. However, depressive symptoms were not associated with sleeping longer four to 12 years later, which corresponded to the genetic findings. Professor Andrew Steptoe, head of Behavioural Science and Health, UCL Institute of Epidemiology and Health Care, said: “Suboptimal sleep and depression increase with age, and with the worldwide phenomenon of population ageing there is a growing need to better understand the mechanism connecting depression and a lack of sleep. “This study lays important groundwork for future investigations on the intersection of genetics, sleep, and depressive symptoms.” People enrolled in the study had an average of seven hours’ sleep a night. More than 10% slept for less than five hours a night at the start of the study period, rising to more than 15% at the end of the study. The proportion of people classed as having depressive symptoms increased by about three percentage points, from 8.75% to 11.47%. In the study, data on sleep and depressive symptoms were combined from two Elsa surveys conducted two years apart, as sleep duration and depression are known to fluctuate over time. Sleep duration and depression are both partly inherited from one generation to the next. Earlier studies have suggested depression is about 35% heritable, and that genetic differences account for 40% of the variance in sleep duration. Read More World Osteoporosis Day: The risk factors and early warning signs everyone needs to know about How to support a child with a stammer From colourful gowns to drones, these wedding trends are set take over 2024 Call The Midwife ‘should come with a health warning’ Halloween: 10 wicked ways to kit out your haunted house Black magic: Go back to black this season with the catwalk-inspired trend

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October 20 marks World Osteoporosis Day – but despite being a relatively common condition, many people are unaware they’re at risk. According to Age UK, osteoporosis – which is associated with weakened bones and often referred to as a ‘silent disease’, as symptoms can creep up on people – affects approximately three million people in the UK. Yet, many only find out they have it when they break a bone. “[Osteoporosis] is a condition characterised by weakened bones, making them more prone to fractures,” explains Dr Zulqarnain Shah, a medical director at SSP Health. “It occurs when the body loses too much bone or makes too little bone, or both. Diagnosis of osteoporosis typically involves a combination of medical history, physical examination, and specialised tests, such as bone mineral density scans,” Shah adds. Could I be at risk of osteoporosis? According to Age UK, around half of women over 50, and around one in nine men in the same age group, will experience a fracture due to osteoporosis. However, several risk factors contribute to the development of the condition, meaning some people may be more likely to get it. “These include menopause, low calcium and vitamin D intake during younger years, family history, a sedentary lifestyle, smoking, excessive alcohol consumption, and certain medications,” explains Shah. “While it may not be possible to prevent all cases of osteoporosis, adopting a healthy lifestyle with regular weight-bearing exercise, a balanced diet rich in calcium and vitamin D, and avoiding smoking and excessive alcohol intake can help reduce the risk.” Being aware of osteoporosis can be particularly important if you have a family history. “A family history of osteoporosis or fragility fractures can indicate an increased risk,” explains Dr Elise Dallas, GP at The London General Practice. Other things that increase risk include having a history of “rheumatoid arthritis, low levels of oestrogen due to early menopause, anorexia nervosa or Turner’s syndrome, hyperthyroidism, parathyroid disease, Crohn’s and coeliac disease, and conditions that cause long periods of immobility”, adds Dallas. What are the symptoms of osteoporosis? When you have osteoporosis, you may suffer from “increased fracture risk, height loss, and chronic pain”, says Shah. “Fractures associated with osteoporosis are known as ‘fragility fractures’, which can occur with minimal impact. Fractures commonly occur in the spine, hip, and wrist, and can lead to significant pain, disability, and reduced quality of life,” he explains. Are there any early warning signs? Shah says: “Early signs of osteoporosis may not be apparent until a fracture occurs. However, a precursor condition called osteopenia may be detected through scans before the onset of full-blown osteoporosis.” Osteopenia is where the density of the bones decreases, but not thoroughly enough to be classed as osteoporosis. There are no real symptoms however, so it can only be detected with scans. The good news is, lifestyle measures and sometimes treatment can help prevent it getting worse. How is osteoporosis treated? Treatment for osteoporosis is mostly aimed at “strengthening bones and preventing fractures”, says Shah. “This typically involves a combination of lifestyle modifications, such as exercise and dietary changes, along with medication. “Medications may include calcium, vitamin D and bisphosphonates, hormone therapy for postmenopausal women, selective oestrogen receptor modulators (SERMs), and other options. “SERMS help manage the way oestrogen interacts with your body and has a similar impact on osteoporosis as hormone replacement therapy, to help mitigate the impacts of hormones on osteoporosis,” Shah explains. “Regular monitoring and adherence to treatment plans can help slow down or stop the progression of osteoporosis. A bone density scan – also known as a DEXA scan – can help monitor the progress of a condition and may be done at three to five-year intervals to assess progress. “Once a patient has been on bisphosphonates for five years, they may go on a ‘pill holiday’ for a couple of years, though the benefits of taking bisphosphonates continue long after the medication is stopped.” Getting support and advice to manage any pain and mobility challenges and reduce the risk of falls and injuries can also be very important for people living with osteoporosis, along with finding ways to stay active. If you are worried about your bones and osteoporosis risk you can reach out to charities like the Royal Osteoporosis Society and find out about your risk level. Read More How to support a child with a stammer From colourful gowns to drones, these wedding trends are set take over 2024 Call The Midwife ‘should come with a health warning’ Halloween: 10 wicked ways to kit out your haunted house Black magic: Go back to black this season with the catwalk-inspired trend How to prep your home for when the clocks go back

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