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By Linda Pasquini (Reuters) -Hugo Boss has raised its sales and profit outlook after reporting a 20% jump in second-quarter

Irregular sleep patterns may be linked to harmful bacteria in your gut, new research suggests. The study is the first to find multiple associations between social jet lag – the shift in internal body clock when sleeping patterns change between workdays and free days – and diet quality, diet habits, inflammation and gut microbiome (bacteria) composition. According to the findings, even a 90-minute difference in the midpoint of sleep – half-way between sleep time and wake-up time – can encourage microbiome that has negative associations with health. Previous research has suggested that working shifts disrupts the body clock and can increase risk of weight gain, heart problems and diabetes. This is the first study to show that even small differences in sleep timings across the week seems to be linked to differences in gut bacterial species Dr Wendy Hall King’s College London However, according to researchers from King’s College London there is less awareness that the body’s biological rhythms can be affected by smaller inconsistencies in sleeping patterns. This is due to people working regular hours waking early with an alarm clock on workdays compared to waking naturally on non-workdays. Senior author Dr Wendy Hall from King’s College London, said: “We know that major disruptions in sleep, such as shift work, can have a profound impact on your health. “This is the first study to show that even small differences in sleep timings across the week seems to be linked to differences in gut bacterial species. “Some of these associations were linked to dietary differences but our data also indicates that other, as yet unknown, factors may be involved. “We need intervention trials to find out whether improving sleep time consistency can lead to beneficial changes in the gut microbiome and related health outcomes.” First author Kate Bermingham, from King’s College London and senior nutrition scientist at ZOE, said: “Sleep is a key pillar of health, and this research is particularly timely given the growing interest in circadian rhythms and the gut microbiome. “Even a 90-minute difference in the mid-point of sleep can encourage microbiota species which have unfavourable associations with your health.” Researchers suggest the composition of the microbes in the gut may negatively or positively affect health by producing toxins or beneficial products. Specific species of microbes can correspond to an individual’s risk of long-term health conditions such as diabetes, heart disease and obesity. The microbiome is influenced by what food someone eats, which makes the diversity of the gut adjustable. Researchers assessed a group of 934 people from the ZOE Predict study, the largest ongoing nutritional study of its kind. They looked at blood, stool and gut microbiome samples, as well as glucose measurements in people whose sleep was irregular compared to those who had a routine sleep schedule. Unlike past research, the group consisted of mainly lean and healthy individuals with most of them getting more than seven hours sleep throughout the week. The study, published in The European Journal of Nutrition, found that just a 90-minute difference in the timing of the midpoint of sleep is associated with differences in what the gut microbiome is made up of. According to the findings, having social jet lag was associated with lower overall diet quality, higher intakes of sugar-sweetened beverages, and lower intakes of fruits and nuts. This may directly influence the abundance of specific microbiota in the gut, researchers say. Three out of the six microbiota species more abundant in the social jet lag group have what researchers describe as unfavourable associations with health. They are linked with poor diet quality, indicators of obesity and cardiometabolic health, like heart attack, stroke, and diabetes, and markers in your blood related to higher levels of inflammation and cardiovascular risk. Previous research has found social jet lag is associated with weight gain, chronic illness and mental fatigue. Dr Sarah Berry from King’s College London and chief scientist at ZOE added: “Maintaining regular sleep patterns, so when we go to bed and when we wake each day, is an easily adjustable lifestyle behaviour we can all do, that may impact your health via your gut microbiome for the better.” Read More Charity boss speaks out over ‘traumatic’ encounter with royal aide Ukraine war’s heaviest fight rages in east - follow live N-Dubz cement comeback with first new album in 13 years Babies as young as four months have taste in fine art, study shows ADHD symptoms in children can be transformed with brain stimulation therapy

GDANSK Poland's mBank expects the level of write-offs to be lower in future quarters compared with levels in

Anorexic YouTuber Eugenia Cooney appears disturbingly thin in her recent video

Barcelona wrapped up their pre-season tour of the United States with a 1-0 victory against AC Milan in Las Vegas. Ansu Fati scored a stunning goal to secure victory for the Spanish champions.

When Ford Motor Co.’s UK boss visited the automaker’s massive production complex in Turkey last week, temperatures reached

Watch live as Pope Francis arrives in Portugal on Wednesday, 2 August, for World Youth Day. The event was created by the late Pope John Paul for young Catholics in their teens or early 20s. It is held every two or three years in a different city and is often dubbed the "Catholic Woodstock." This year's event is the first time it has been held since 2019 due to the coronavirus pandemic. The pontiff will take part in a welcoming ceremony at Figo Maduro Air Base in Lisbon before visiting the Portuguese president, Marcelo Rebelo de Sousa, later this morning. As part of the festival, young people will meet for Masses, vigils and other social and religious gatherings. Around 330,000 young people have registered and many more are expected to attend, the Vatican has said. Portuguese authorities have predicted more than one million attendees. Read More Pope Francis will be in Portugal for 5 days. Here's what he will visit As the pope heads to Portugal, he is laying the groundwork for the church's future and his legacy A rebounding Pope Francis adds an overnight visit to France to his busy travel schedule

Net foreign assets held by Egypt’s commercial banks went into a record deficit in June, as a lack

BEIJING (Reuters) -Volkswagen is in talks with Chinese electric vehicle startup Zhejiang Leapmotor Technology about the possibility of cooperation for

Donald Trump is in trouble once again. The former US president has been indicted over trying to mess with the 2020 election. He is accused of four counts including conspiracy to defraud the US, tampering with a witness and conspiracy against the rights of citizens. The indictment caps an inquiry into events surrounding the 6 January 2021 riot at the US Capitol. It is not the only issue Trump is facing. He has already been charged in two other cases: with mishandling classified files and falsifying business records to cover up a hush-money payment to the porn star Stormy Daniels. Sign up to our free Indy100 weekly newsletter Nevertheless, he called the case "ridiculous" and denied wrongdoing. His campaign said: "The lawlessness of these persecutions of President Trump and his supporters is reminiscent of Nazi Germany in the 1930s, the former Soviet Union, and other authoritarian, dictatorial regimes." It added: "These un-American witch hunts will fail." The election investigation has focused on Trump's actions in the two-month period between his loss to Joe Biden and the riot in Washington DC. The 45-page indictment lists six unnamed co-conspirators: four lawyers, a justice department official and a political consultant. The court document accuses Trump of a "conspiracy to impair, obstruct, and defeat the federal government function through dishonesty, fraud and deceit". The man leading the inquiry, special counsel Jack Smith, said: "The attack on our nation's capital on January 6 2021 was an unprecedented assault on the seat of American democracy. "As described in the indictment it was fuelled by lies." Here's how people reacted: Mike Pence said the indictment against Trump was “an important reminder [that] anyone who puts himself over the constitution should never be president of the United States”. He also said that though Trump was entitled to be presumed innocent, “his candidacy means more talk about January 6 and more distractions”. “Trump’s presidential bid is driven by an attempt to stay out of prison and scam his supporters into footing his legal bills,” former Texas congressman Will Hurd said. “Furthermore, his denial of the 2020 election results and actions on January 6 show he’s unfit for office.” He added: “As Republicans we need to prioritise offering solutions to difficult issues affecting all Americans … if we make the upcoming election about Trump, we are giving Joe Biden another four years in the White House.” Trump also got some supportive messages from Republicans who believe it to be a distraction attempt to undermine the former president. Trump is due to appear in court on Thursday in Washington DC. This story is not going anywhere. Have your say in our news democracy. Click the upvote icon at the top of the page to help raise this article through the indy100 rankings.

India’s overall unemployment rate fell in July as rural areas saw increased demand for agriculture labor with the

A cornerstone of the European Union’s sustainable finance package should be streamlined by the UK to make it