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TD Bank Group reported a fall in its fourth-quarter profit on Thursday, as Canada's second-largest lender set aside

Jeff Bezos and his high school sweetheart, Ursula Werner, who described him as 'wicked and smart', kept in touch over the years

LAS VEGAS--(BUSINESS WIRE)--Nov 30, 2023--

LONDON & NEW YORK--(BUSINESS WIRE)--Nov 30, 2023--

MARLBOROUGH, Mass.--(BUSINESS WIRE)--Nov 30, 2023--

There’s political blood in the water after a series of blows to New York City Mayor Eric Adams,

Our canine companions could soon be enjoying much longer lifespans, if a drug which claims it can extend dogs’ lives eventually gets approved. The drug, made by a tech firm in California, just cleared a vital hurdle to doing just that, after it got partial approval by regulators in the US. Loyal, a San Francisco-based company founded in 2020, has been researching how it can increase dogs’ lifespans – in particular larger breeds, which tend to die younger. Large and “giant” breeds tend to live to between eight and 12 years. Smaller dogs, such as Chihuahuas, can keep going to the ripe old age of 20. Loyal’s main product, the catchily-titled LOY-001, is designed not only to extend dogs’ lives but also maintain their quality of life. Now, it has passed the “reasonable expectation of effectiveness” test, set by regulators at the US’ Food and Drug Administration. Loyal’s chief executive, Celine Halioua, said: "Loyal was founded with the ambitious goal of developing the first drugs to extend healthy lifespan in dogs. "This milestone is the result of years of careful work by the team. We'll continue to work just as diligently to bring this and our other longevity programs through to FDA approval." Selective breeding of dogs has caused higher levels of hormones which help the animals grow faster. That is also believed to reduce their lifespan, the company said. Big dogs tend to have more of this hormone than their smaller counterparts. Animal rights activists are not yet convinced. Some experts fear it will only serve to extend animals’ suffering. Loyal, on the other hand, says the drug aims to treat doggy diseases which are associated with ageing through preventing them, rather than waiting for the animals to get sick before treating them. The company said that the drug could be available to US customers as early as 2026. So that’s plenty of time for walkies between now and then. How to join the indy100's free WhatsApp channel Sign up to our free indy100 weekly newsletter Have your say in our news democracy. Click the upvote icon at the top of the page to help raise this article through the indy100 rankings.

U.S. stock index futures edged higher on Thursday, ahead of a reading later in the day that is

Authorities in a Pakistani province are setting targets for police to arrest and deport hundreds of thousands of Afghans who are in the country illegally

Europe needs more liquefied natural gas to provide relief to its market as the region recovers from last

Joe Rogan has been under constant scrutiny due to his opinions about cancel culture

The Premier League confirms its nominees for 2023 November Player of the Month.