Grant Shapps visits Kyiv as UK backs Ukraine nuclear power
The government says a loan guarantee will help improve Ukraine's energy security.
2023-08-23 08:15
How did surgeons carry out Britain’s first womb transplant?
Surgeons worked all day and into the night to ensure Britain’s first womb transplant went smoothly. Its success is down to meticulous research, years of sharing knowledge between experts around the globe, and the hard work and dedication of doctors Professor Richard Smith, from Imperial College London, and Isabel Quiroga, from the Oxford Transplant Centre. Around 50 babies have been born worldwide as a result of womb transplants, which give women missing a functioning uterus a chance to have a baby. In the first UK case, the operation to remove the womb from the recipient’s 40-year-old sister lasted eight hours and 12 minutes, with surgeons leaving her ovaries behind to prevent pushing her into early menopause. One hour earlier, surgeons began operating on the 34-year-old recipient, preparing her body to receive the donated organ. This operation lasted nine hours and 20 minutes, with the surgical team experiencing some difficulties including a higher-than-expected blood loss of two litres. However, after just 10 days, the recipient was well enough to leave the hospital and has continued to have a good recovery. She is also having regular periods, which shows the womb is working well. Her sister was discharged five days after her donor operation and has also made a good recovery. Removing a womb is a similar operation to a radical hysterectomy, according to Prof Smith, who as well as being a gynaecological surgeon is the clinical lead at the charity Womb Transplant UK. He and Miss Quiroga led the team of more than 30 staff who worked on the transplant one Sunday in February. Prof Smith and Miss Quiroga removed the older sister’s womb, cervix and fallopian tubes, plus crucial blood vessels around the organ. The main vessels are the uterine arteries running into the womb, but the surgeons also aimed to collect some of the larger internal vessels that lead into the smaller branch of the womb. Prof Smith said surgeons doing these operations have to retrieve veins involved in the drainage of the womb. “One of the amazing things is that my surgical skill-mix as a cancer surgeon is to remove organs with a margin of normal tissue, while sealing the vessels as I go,” he said. “Transplant surgical skills are different – that is to remove a normal organ with the best number of non-sealed vessels as you can. “Isabel and I operate together with no ego – it just flows backwards and forwards across the table.” He added: “The day itself was truly humbling. We turned up at 7am at the Churchill transplant centre with the donor and the recipient families, then we went into a pre-op huddle. Those in the huddle included surgeons, nurses, anaesthetists and technicians. Prof Smith and Miss Quiroga worked to remove the womb, before the organ was prepared for transplantation by a “back table” team. “This was an organ which had a very, very unusual blood supply,” Prof Smith said. “In fact, it had a set of blood vessels which I’ve never seen in my entire career. They made my dissection a bit harder than it might have been, but we got there.” In the theatre next door, one hour before the retrieval of the womb was completed, surgeons began to operate on the donor’s younger sister to enable her to receive the womb. Prof Smith and Miss Quiroga switched from donor to recipient and Prof Smith removed the vestiges of the underdeveloped womb the recipient was born with. Meanwhile, the organ was packed and transported between the two theatres under sterile conditions to prevent contamination. A sterile bag with a cold perfusion solution contained the womb, which was then placed into a container with ice. During surgery, ligaments attached to the womb were attached to the recipient to help the womb stay in a relatively fixed place so it does not move around the pelvis. The most important part of the transplant operation was the joining of the very small vessels that give the blood supply to the womb. This was the most delicate and difficult part of the operation and was led by Miss Quiroga. Once all the vessels were connected, the donor’s vaginal cuff – around a 1cm part – was stitched into her sister’s vagina. If and when the recipient is able to complete her family, the womb will be removed six months later to prevent her from needing immunosuppressants for the rest of her life. Prof Smith said: “We know that the chance of failure at the point where the uterus goes in – if you look at the world literature – is 20 per cent to 25 per cent. And that failure is usually on the basis on sepsis and thrombosis. So technically, we are up to the job, but what happens thereafter can be scary. “Once you get to three or four days later, the chance of failure drops to probably less than 10 per cent. “Once you get to two weeks – and at the point where the woman has a period – the chance of her having a baby at that point is very high and the chance of failure has dropped to low. But those first two weeks – it’s very scary as a surgeon to watch and wait.” Biopsies to check the womb was functioning were read in London but then also confirmed by an expert team in the US at Baylor University Medical Centre in Dallas, where other womb transplants have been performed. Prof Smith said the procedure gives new hope to women born with devastating conditions. He said: “You’ve got girls, maybe 14, who have not had periods, they go to the GP and a scan shows there is no uterus. Absolute catastrophe. “Up until now, there’s been no solution for that, other than adoption or surrogacy... That’s not the case now. It’s really exciting.” On whether transgender women may also benefit from the operation, Prof Smith said that was still a long way off. He said the pelvic anatomy, vascular anatomy and shape of the pelvis are different, and there are microbiome issues to overcome. “My own sense is if there are transgender transplants that are going to take place, they are many years off. There are an awful lot of steps to go through. My suspicion is a minimum of 10 to 20 years.” Miss Quiroga said the living donor programme to date in the UK has focused on women with relatives who are willing to give their wombs. “It will come to a point where we will have friends or altruistic donors, like we have with many other transplants, but at the moment we’re only focused on people who have come forward with relatives,” she said. Read More Bursts of activity that make you huff and puff ‘linked to reduced cancer risk’ Fiona Phillips, 62, reveals she has Alzheimer’s disease Woman has all her teeth removed after rare vomiting condition causes them to fall out Bursts of activity that make you huff and puff ‘linked to reduced cancer risk’ Fiona Phillips, 62, reveals she has Alzheimer’s disease Woman has all her teeth removed after rare vomiting condition causes them to fall out
2023-08-23 07:19
Teamster members ratify deal at UPS, putting strike threat to rest
Rank-and-file members of the Teamsters union have overwhelmingly ratified a five-year deal with UPS, putting an end to the threat of a crippling strike.
2023-08-23 04:48
UPS employees ratify new five-year labor agreement, union says
Teamsters-represented UPS workers voted to approve a five-year labor contract that covers about 340,000 U.S. employees at the
2023-08-23 04:22
Here Are the Key Takeaways From Arm's IPO Filing
SoftBank Group Corp.’s Arm Holdings Ltd. dropped a more than 300-page filing ahead of what’s expected to be
2023-08-23 02:23
League of Legends Prime Gaming Capsule Aug. 2023: How to Claim
League of Legends Prime Gaming rewards for August are now live, giving fans an opportunity to earn another capsule.
2023-08-23 01:55
Georgia Rico case: John Eastman surrenders to authorities
Ex-Trump lawyer John Eastman is one of two accused in the Georgia indictment to surrender on Tuesday.
2023-08-23 00:47
Nigeria's ex-oil minister Diezani Alison-Madueke charged with bribery in the UK
Diezani Alison-Madueke is alleged to have accepted financial rewards for awarding oil contracts.
2023-08-22 23:54
Spain World Cup team receives heroes’ welcome at Madrid victory parade
Spain’s Women’s World Cup champions received a heroes’ welcome as they arrived home to a victory parade on the streets of Madrid. Fans lined the streets of the Spanish capital as the victorious team celebrated with on an open-top bus. They lated took to a stage where the players sang with the crowd and tossed match-winner and captain Olga Carmona into the air. Spain beat England 1-0 to win the World Cup. It is the first time they have won the competition since its inception in 1991.
2023-08-22 23:51
The ‘huge ego’ at the centre of Spanish football’s sexism storm
Even before Luis Rubiales had planted a kiss on Jenni Hermoso’s lips during Spain’s World Cup celebration, other officials in the stadium were so struck by his behaviour that they were sending around videos. One, confidentially sent to The Independent, shows the president of the Spanish football federation appearing to grab his crotch in triumph. The gesture, which goes back to Ancient Rome, is generally taken to mean “I’m the man”. It is certainly an aggressively masculine gesture, making it all the more out of place at a women’s football tournament that is defined by its inclusivity. It feeds into one of many growing arguments in Spain, that Rubiales did not know how to comport himself at such an event, raising further questions over his suitability to oversee the federation. That the Queen of Spain and her 16-year-old daughter were close to him has only added to that. There is still the sense that Rubiales doesn’t really know what he did wrong in the kiss on Hermoso. If a widely criticised non-apology was not indicative enough, there were his litany of comments before it. Rubiales had described those who took issue with his “public show of affection” as “idiots”, “stupid”, “fools” and “losers” before summing it all up as “bulls**t”. His subsequent apology then pretty much amounted to being sorry if anyone was offended. That happens to amount to a lot of people, who are queuing up to condemn the Spanish official in a controversy that is nowhere near quietening down. Miquel Iceta, the minister for culture and sport in Spain, described it as “unacceptable”. Yolanda Diaz, the second deputy prime minister of Spain, has said Rubiales should resign because “a woman has been harassed and assaulted”. Irene Montero, the minister for equality, went furthest and described it as a “form of sexual violence”. Such words are beginning to change the view of some in Spanish football that as usual, nothing will happen. The situation has now gone beyond pressure growing. While the kiss is obviously sufficient for such a controversy on its own, it comes amid a wider context that goes beyond Rubiales’ backing of manager Jorge Vilda despite player complaints that included not being allowed to lock doors of their hotel rooms on international duty until 2019. Sources within Spanish football were using words like “embarrassment” and “a disgrace that people like this represent our game”. Newspaper El Pais meanwhile ran an editorial lamenting how a moment of glory for Spain’s women’s footballers, who were enjoying the praise of the whole planet, was overshadowed by the behaviour of a man. Rubiales has previously caused such ructions in the game, however, that other figures were all too willing to privately Whatsapp other headlines. Among them was the story: “The ex-boss of Rubiales’ cabinet says he paid for orgies with federation money,” in relation to private parties reportedly organised. Rubiales denies it. Another read: “Luis Rubiales acquitted of the accusation of assault of the architect who renovated his house,” in a case that also saw him accused of using money from the player’s union – of which he was president – to pay for the work. And then: “Rubiales deal with [Gerard] Pique for a €24m pitch to bring the Super Cup to Saudi Arabia – ‘you are left with six kilos’”, after a series of leaks showed some controversial deals with the former Spanish defender. Up to all of this, however, he had probably been best known outside Spain for the bombshell decision to sack men’s manager Julen Lopetegui two days before the 2018 World Cup, a call that sent the Spanish team into a tailspin last-16 exit. It’s one of those historical quirks that the situation almost represents the inverse of that with Vilda, whom he has stood by. In the case of Lopetegui, Rubiales felt he had no choice because the manager had disrespected the federation by agreeing to take a job with Real Madrid after that World Cup without informing them. With Vilda, Rubiales felt Spain’s rebel players – some of whom boycotted the Women’s World Cup – had disrespected both the manager and the federation, so backed the manager adamantly. It was repeatedly pointed out that he and Vilda have a strong relationship and Vilda’s father, Jorge, is currently head of the Royal Spanish Football Federation (RFEF)’s women’s football department. Either way, compromise was never much of a consideration in either situation, although the latter did force changes to women’s team preparation standards and facilities. Some of the victorious players remain aggrieved they even had to ask and Ballon d’Or winner Alexia Putellas made a noteworthy comment in the moment of victory. “You’ve seen that the minute women's footballers believe a little and are provided with basic facilities, everything comes out better.” Rubiales’ defenders – and there are more than a few – would say this shows an evolution. He was less than a month into the job when the Lopetegui incident happened in June 2018 and was already seen as a significant improvement on predecessor Angel Maria Villar, who was suspended as president after being detained the previous July on allegations of collusion, embezzlement and falsifying documents. On sacking Lopetegui, Rubiales came out with the following: “These are the values of the new federation and whoever doesn't like it will have to get used to it.” Rubiales rose to the role after his work with the Association of Spanish Footballers, where his experience in leading squads through bankruptcy and administration at lower-profile clubs while still a player was greatly valued. One such call to help actually came at his last club, which happened to be Scottish side Hamilton Academical. One of the last things he heard on his fourth and final appearance in Scotland – a 4-1 defeat at Rangers – was the chant: “Baldy bastard, what’s the score?” A defender, Rubiales wasn’t seen as having the typical technical skill of Spanish players, but was respected for his tenacity. He was at Hamilton in the season that ended with Spain winning the men’s World Cup in South Africa, which somewhat cuts across any purported wider influence on the women’s success. It was Spain’s coaching revolution around the turn of the millennium that led to the rise of both of Spain’s world champions, and Rubiales was at clubs like Gaudix and Lleida as this was happening. It should be stressed he is seen as a moderniser in other ways, though, for a federation that badly needed it. It is under Rubiales that a department of integrity and security has been created. And “Rubi”, as he insists staff at the federation call him, was also influential in a crucial move that has been seen as decisive in potentially bringing the 2030 World Cup to Spain. Although many had felt Saudi Arabia would win that bid through their growing influence, bringing in Morocco with Portugal and Spain has split the African vote and essentially forced the Gulf state out of the process. Those who have worked with Rubiales at Uefa level meanwhile describe him as “ambitious” and “capable”, but with a “huge ego”, that leads to a lot of abrasiveness. He has already fallen out with the successive regime at the player’s union and La Liga president Javier Tebas. Many would say that is nothing new. Otherwise, that perceived modernity at federation level now stands in contrast to the regressive behaviour of the last few days. El Pais described the kiss as “like a bad joke from Benny Hill”. Unfortunately, it is only getting more and more serious. Rubiales looked like he was certainly feeling it at Monday’s victory parade. There were no videos of his behaviour there as he was very restrained and didn’t appear on stage. In the words of one source, it’s about time. Read More How not to win a World Cup: Spain, Jorge Vilda and the story of a complicated victory Spanish football president’s kiss was an abuse of power that never should have happened Spain boss Jorge Vilda appears to grab breast of female coach during World Cup final Spanish PM condemns FA president over ‘unacceptable’ kiss at World Cup final Spain boss Jorge Vilda appears to grab breast of female coach during World Cup final Spanish FA chief says kissing footballer ‘tarnished celebration’ of World Cup win
2023-08-22 20:48
Manchester United made the right Mason Greenwood decision for all the wrong reasons
Manchester United were drawing 0-0 with West Ham in January 2022 when, with the minutes ticking down, Ralf Rangnick brought on Edinson Cavani and Anthony Martial. It proved a fine double change, with each involved in Marcus Rashford’s injury-time winner. Its significance now, however, is rather different. Mason Greenwood was one of those removed: now his 129th United appearance will prove his last. What should have been a glittering career at Old Trafford in effect ended a few months after his 20th birthday. For now, he is still under contract, but in limbo. A six-month investigation has brought the conclusion that Greenwood will not play for United again. He may be sold or loaned out. His contract could be paid up. He has not been sacked, which United say they would have done had they determined he was guilty of attempted rape, assault or coercive and controlling behaviour, the charges first levelled and then dropped by the Crown Prosecution Service. But in January 2022, a week after Greenwood’s last game, pictures emerged of a bruised, bleeding woman, audio of a man seemingly threatening to rape her. That remains impossible to forget; to forgive, for many. Greenwood will not play for United again and nor should he. And so it is possible they reached the right decision, perhaps in the wrong way, possibly for the wrong reasons. There were plans to bring Greenwood back – though United insist they simply considered a variety of scenarios – and perhaps the most telling phrase in chief executive Richard Arnold’s statement was: “Further, this case has provoked strong opinions, and it is my responsibility to minimise any distraction to the unity we are seeking within the club.” Had Greenwood played again, it would have been Manchester Divided, not United. There were protests before Monday’s game against Wolves; there would have been far more were he to return to the team. The television presenter Rachel Riley said she would have stopped supporting United had Greenwood represented them again. She would not have been alone in that, either. The Manchester United Supporters Trust backed the decision not to bring him back, though not the lack of consultation for fans. There were staff at Old Trafford who felt it would be wrong to recall him, some of whom would not have wanted to encounter Greenwood in their line of work, maybe some who would have considered quitting their jobs. Perhaps United originally underestimated the strength of feeling. Perhaps, too, there were commercial considerations; the club’s image would have suffered considerable damage if he played, and has already been tainted. Because there is a tendency – often a wish – to celebrate footballers. But could United fans have cheered if Greenwood scored for them again? Would they have been in the awkward position of loving the shirt, hating the man wearing it? Footballers are imperfect people, as we all are, and some more than most, but there is a matter of character. The word is often used in football – when a team gets a late equaliser, when a player makes a comeback from injury – but there is a deeper meaning. If there is a moral test, Greenwood has failed it. Those who have been convicted of criminal offences have a right to work, let alone those who have not, but playing for Manchester United is not merely a job: it is a privilege. And if that invites questions as to at which level of football, if any, that stops being true and there is no definitive answer as to where Greenwood should be allowed to play, there could be a similar reaction at other clubs in England, should they try and sign him; it is still harder to imagine a scenario where he adds to his one cap for England. None of which makes him the victim. United argue they conducted a thorough investigation, showing concern for the woman in question, who has lifelong anonymity for legal reasons, speaking to her mother, showing her their findings, as well as a duty of care to Greenwood. Arnold said he was “satisfied that Mason did not commit the acts he was charged with”. None of which necessarily makes Greenwood innocent in the court of public opinion; as he accepted himself, his behaviour was wrong. “I fully accept I made mistakes, and I take my share of responsibility for the situations which led to the social media post,” he said. Yet if time is required to see if he does, as he has pledged to do, lead a better life and if there are reasons to keep some of the detail confidential, it would help to know if he has, for instance, spoken to a counsellor, or to victims of rape and domestic abuse, or donated to suitable charities. And if not, why not; these would not be automatically be admissions of guilt, but they would be a recognition he took the issues seriously. His other concern may seem trivial in comparison, though football can be a juxtaposition of the relevant and the irrelevant. But he has to find a club, with United pledging their help to do so. If his prime responsibility is to be a better partner and a good father, as he vowed, he may have a duty to himself to try and rescue his career and realise some of his potential. The teenage prodigy – the man Ole Gunnar Solskjaer deemed the best finisher at Old Trafford – had the talent to be a United great; he has not been found guilty of a crime or sacked by United, but it is still his fault he never will be. Read More Mason Greenwood will not play for Manchester United again, club announce Mason Greenwood speaks out on Manchester United exit: ‘I made mistakes’ Mason Greenwood timeline: How the Manchester United star fell from grace
2023-08-22 20:26
US economy holds its breath ahead of UPS Teamsters contract vote
By Lisa Baertlein and Priyamvada C The U.S. economy will face a key test on Tuesday when the
2023-08-22 18:23