Zach Edey's stature makes him one of the tallest and heaviest players in the world of college basketball

Provides an overview of St Pierre and Miquelon, and key facts about this French Atlantic territory.

A marijuana delivery driver named Nicholas Aliff filed the lawsuit against the Nelk Boys, claiming that he was unaware of the prank

One of the scientists whose work pioneered the development of medications such as Ozempic and Wegovy has revealed why life may become “so miserably boring” after two years of using the drug. Ozempic is an FDA-approved medication used for the treatment of type 2 diabetes. It works by mimicking a hormone called glucagon-like peptide 1 (GLP-1), which regulates blood sugar levels and slows down the rate at which food leaves the stomach, often creating the feeling of fullness. These semaglutide injections – sold under the brand names Ozempic and Wegovy – have soared in popularity as many people, including Hollywood celebrities, have used it for weight loss. What’s more, people have also found Ozempic has been effective in curing their addictive habits, like drinking, smoking, shopping, or nail biting. However, because of Ozempic’s increasing popularity, it has led to national shortages of the type 2 diabetes treatment – leaving those who actually need it without. In an interview with Wired, professor Jens Juul Holst – who received the Warren Alpert Foundation Prize in 2021 for his work developing treatments based on the GLP-1 hormone – spoke about the effects of Ozempic, and why he believes many people will stop taking the medication after just a few years. “What happens is that you lose your appetite and also the pleasure of eating, and so I think there’s a price to be paid when you do that,” Holst told Wired. “If you like food, then that pleasure is gone. The craving for food for some people is taken away when they take GLP-1 drugs.” He continued: “That may eventually be a problem, that once you’ve been on this for a year or two, life is so miserably boring that you can’t stand it any longer and you have to go back to your old life.” Holst added that medications like Ozempic and Wegovy have been on the market since 2005, though studies show that these people don’t stay on them for very long. “It’s just like every other drug, they don’t stay on it for many reasons,” he explained. “One of the reasons, as I said, is that once you have tried it and you realise you’ve lost interest in food, then that may be enough.” “We don’t know why people stop taking these drugs, but we know for a fact that they do stop. They do that all over the world.” A 2020 study found that 70 per cent of people who took GLP-1 drugs for type 2 diabetes stopped taking them within two years. However, this could pose a problem for many patients taking semaglutide injections. Research has found that people who stopped taking Ozempic or Wegovy for weight loss experienced weight rebound. A trial published in April 2022 saw participants gain back two thirds of the weight they had lost after 68 weeks of taking semaglutide. As for celebrities who use the once-weekly injection for weight loss, despite not having diabetes or clinical obesity, Hans instead called attention to the “many terrible problems” that those with diabetes have struggled with by not having drugs like Ozempic readily available. “Have you ever visited a diabetes hospital? It’s really deplorable,” he said. “People come in with amputated limbs and compromised cognitive functions and heart problems or they can barely move – they’re miserable and depressed. It’s really serious. There is so much you can improve with a drug that is not only a weight-loss drug but is also an anti-diabetic.” Amidst the popularity of semaglutide injections, the US Food and Drug Administration has issued warnings for consumers not to use off-brand versions of Ozempic or Wegovy, because they may not include the same GLP-1 hormone used in approved medications. Earlier this month, agency officials reported problems with patients using compounded versions of semaglutide – which combines traditional semaglutide with other ingredients. These drugs are not FDA-approved, and the agency does not verify the safety or effectiveness of compounded drugs. Consumers should only use drugs containing semaglutide with a prescription from a licensed health care provider and obtained from a state-licensed pharmacy or other facilities registered with the FDA, the agency said. Read More What is ‘Ozempic face’? Doctors warn about facial ageing side effect of diabetes medications How does Wegovy work? The ‘game changing’ weight loss drug beloved by Hollywood FDA warns against using off-brand versions of Ozempic, Wegovy for weight loss Pregnant Stassi Schroeder admits she wants to ‘try’ Ozempic after giving birth Doctors warn about ‘Ozempic face’ side effect of medications Amy Schumer says she stopped taking Ozempic because of side-effects

(Reuters) -Shares of AMC Entertainment Holdings Inc tumbled about 17% on Tuesday after shareholders voted in favor of converting the

'RHOSLC' couple John and Lisa Barlow got married in July 2003

ChatGPT, a publicly available language-learning AI, was not designed to create things like crochet or knitting patterns, but what happens when you ask it to do just that? We crocheted some ChatGPT-generated patterns to find out.

Wales warmed up for Euro 2024 qualifying action by cruising to a 4-0 win over Gibraltar in Wrexham. All the goals came in the first half as Kieffer Moore scored twice with Ben Davies and Nathan Broadhead also getting on the scoresheet. After last month’s victory in Latvia, it was the first time Wales had achieved back-to-back wins since November 2021. The performance, especially the opening period, will encourage Wales manager Rob Page ahead of the vital qualifier against Croatia on Sunday, even if Gibraltar’s standing in world football must be taken into account. This was the maiden meeting between the two nations at senior level and also marked Wales’ return to the SToK Racecourse for the first time since beating Trinidad and Tobago there in 2019. The Football Association of Wales were rewarded with a sell-out crowd of 10,008 as fans in the north showed their appetite to support the national team. Page rested several regulars with the Croatia fixture in mind, when Wales will realistically need at least a point to keep alive hopes of automatic qualification for next summer’s European Championship finals in Germany. Davies took over the captaincy in the absence of the injured Aaron Ramsey, the Tottenham defender winning his 81st cap as Gibraltar played the 81st match in their history. Charlie Savage, the 20-year-old son of former Wales midfielder Robbie, Joe Low, Regan Poole and Liam Cullen were handed first caps. Savage, in particular, could be satisfied with his night’s work as he showed composure in possession and exhibited a good range of passing. Gibraltar came into the game 198th in the world with only nine nations below them on FIFA’s rankings table. Preparing to play the Republic of Ireland in Euro qualification on Monday, Gibraltar had suffered six straight defeats and not scored since a 1-0 friendly win over Andorra 11 months ago. The loudest cheer in the opening minutes came when Savage evoked memories of his father with a crunching, but fair, challenge on Tjay De Barr that left the Gibraltar forward on the floor. Broadhead was off target with a couple of efforts before Wales took the lead after 22 minutes from an unlikely source. Skipper Davies rose highest from Broadhead’s corner and Gibraltar’s fallibility in the air was punished again when Moore met Savage’s cross to score expertly off a post. Daniel James, on early for the injured Wes Burns, was causing havoc down the left and forced a sprawling save from Dayle Coleing. The over-worked Gibraltar goalkeeper also denied Savage twice and Liam Walker cleared another Davies effort off the line. Broadhead then took James’ 35th-minute pass and turned smartly to find the top corner of Coleing’s net with a sweet right-footed strike. Cullen twice went close and the fourth arrived on the stroke of half-time as James scampered free again to deliver a perfect cross for the waiting head of Moore. Page made a raft of substitutions at half-time and the contest lost much of its rhythm. The changes also removed the possibility of Wales eclipsing their record 11-0 win against Ireland in 1888. Tom Bradshaw was inches from connecting with a Josh Sheehan cross that flashed across goal, but the second half was largely a nondescript affair. James shook the crowd from their slumber with an angled effort that rattled the woodwork, but Wales had already achieved their objectives heading into Sunday. Read More Steve Clarke confident Scotland’s best performance is good enough to match Spain Lawmakers could allow audio between referees and VARs to be available live Hugo Keenan excited to line up with ‘X-factor’ wings Mack Hansen and James Lowe World Netball president receives damehood at Windsor Castle Andy Murray to withdraw from next week’s Japan Open through injury Johnny Sexton insists Ireland are ready for ‘toughest game we’ve ever faced’

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Somers’ hubby had given her a pair of customized Timberlands that the star had on in her final resting place, a close friend shared

President Joe Biden will announce Thursday that he is tapping a history-making Air Force fighter pilot to serve as the nation’s next top military officer, according to a U.S. official

Texas has started rolling out what is set to become a new floating barrier on the Rio Grande