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Two European defense manufacturing giants are seeking to win a 400 billion rupee ($4.8 billion) order to build

A local government financing vehicle from one of China’s most indebted cities enjoyed overwhelming demand for a yuan

By Helen Reid LONDON H&M is investigating 20 alleged instances of labour abuse at Myanmar garment factories that

By Clare Jim HONG KONG China's financially beleaguered property developer Country Garden promised "five-star living" to the masses

BHP Group Ltd., South32 Ltd. and a unit of Seriti Resources Holdings Ltd. may face a class action

Taking regular Vitamin D supplements may reduce cancer deaths in the population by 15%, according to scientists. Data gathered from the UK Biobank, an online database of medical and lifestyle records of around 500,000 Britons, indicates vitamin D deficiency is linked to an increased cancer mortality risk – particularly in relation to bowel, stomach, prostate, and lung cancers. The researchers said their work, published in Elsevier’s European Journal of Cancer, adds to evidence that vitamin D may have a protective effect against cancer. While the findings do not explain why this happens, the team said one possibility is that vitamin D supplements may induce anti-inflammatory, antioxidant, and DNA damage repair mechanisms, which can thwart mutations that allows tumours to grow. Study author Ben Schottker, an epidemiologist at the German Cancer Research Centre, said: “Our findings identified a statistically significant relationship between vitamin D deficiency and increased mortality among several cancers. “These results can be explained by other studies, which found mechanisms by which vitamin D inhibits cancer growth and metastasis.” The NHS advice is that adults and children over four take a daily supplement containing 10 micrograms of vitamin D throughout the year. According to the Department of Health and Social Care, around one in six adults and almost 20% of children in the UK have vitamin D levels lower than government recommendations. Older people, the housebound and people from black and South Asian communities are more likely to have lower levels of vitamin D. Our findings identified a statistically significant relationship between vitamin D deficiency and increased mortality among several cancers Ben Schottker For the study, the researchers looked at data from more than 400,000 people aged 40–69. In-depth medical information was gathered through blood, urine and saliva samples. A short interview and a questionnaire as used to assess vitamin D consumption as well as lifestyle factors such as alcohol consumption, smoking. Follow-up data on health outcomes were gathered through NHS links as well as care data, cancer screening data, and disease-specific registers. Over a period of nearly 13 years, close to 13,000 people died of cancer. Results showed a majority of the study population had either vitamin D deficiency (21.1%) or insufficiency (34.4%) – used to describe low levels of vitamin D. Of the people involved in the study, only 4.1% regularly took a vitamin D supplement and 20.3% regularly took a multivitamin. Results showed that vitamin D supplement users had 15% lower total cancer mortality and 25% lower lung cancer mortality compared to those who did not take the supplement. The also found researchers found that those with vitamin D deficiency had 42% increased mortality for stomach, 27% for bowel, 24% for lung, and 36% for prostate cancers. Meanwhile those with vitamin D insufficiency were found to have 14% increased bowel cancer mortality and 19% increased lung cancer mortality. The scientists said that the potential to reduce cancer mortality by vitamin D supplementation in populations with low levels should be further explored in new research. Commenting on the study, Dr Jenna Macciochi, senior lecturer in immunology at the University of Sussex, said: “This study adds to the growing body of evidence on vitamin D and cancer. “Vitamin D plays multiple key roles in immune health and the immune system is part of the body’s cancer defence system. “With cancer rates rising and presenting a serious public health issue, its useful to have further insight into the role of vitamin D in the prevention of cancer.” But Dr Macciochi also cautioned that the Biobank data might not be diverse and representative of the whole of the UK population. Alex Ruani, doctoral researcher at University College London and chief science educator at The Health Sciences Academy – who was not involved in the study, said that the exact dosage taken by participants was not ascertained and the risk reduction was not the same for all cancers. She said: “This research doesn’t imply that taking vitamin D3 supplements will for sure lower your risk of death from cancer. “Supplementation may help with consistent vitamin D levels, whereas production from sunlight can be variable and dependent on weather, time of the day, exposure duration, being outdoors or indoors, protective UV wear or sunblock, and many other factors.” She added: “Common food sources of vitamin D3 include full-fat dairy, egg yolks, and fish. “Although toxicity is rare, there is an upper tolerable limit set in the UK, where vitamin D3 supplementation shouldn’t exceed 100 micrograms a day.”

Male joggers, swimmers and cyclists could be cutting their risk of nine cancers, a new study suggests. Researchers found that men with good cardiorespiratory fitness are far less likely to go on to develop cancers of the head and neck, stomach, pancreas, liver, bowel, rectum, kidney, lung and oesophagus. Cardiorespiratory fitness refers to a person’s ability to do aerobic exercise, such as running, cycling and swimming for sustained periods, or even to climb stairs. The new study, published in the British Journal of Sports Medicine, saw experts from Sweden track just over a million men for an average of 33 years. The men involved in the study were conscripted to military service in Sweden between 1968 and 2005. At the start of their conscription the men underwent a battery of tests assessing a number of factors including their height, weight, blood pressure, muscle strength and cardiorespiratory fitness. During the follow-up period, about 84,000 developed cancer. Researchers found that, compared with those with low cardiorespiratory fitness, men with a higher level of cardiorespiratory fitness were: – 19% less likely to develop head and neck cancer.– 39% less likely to develop cancer of the oesophagus (food pipe).– 21% less likely to develop stomach cancer.– 40% less likely to have liver cancer.– 18% less likely to develop bowel cancer and 5% less likely to develop cancer of the rectum– 20% less likely to develop kidney cancer.– 42% less likely to develop lung cancer.– 12% less likely to develop pancreatic cancer. “These results could be used in public health policymaking, further strengthening the incentive for promoting interventions aimed at increasing [cardiorespiratory fitness] in youth,” the authors wrote. The researchers did find that higher cardiorespiratory fitness was linked to a slight (7%) increased risk of prostate cancer and a 31% increased risk of skin cancer. A previous study examining the same data set suggested the slight increase in risk for prostate cancer was not linked to a higher rate of aggressive prostate cancer or prostate cancer death, and could be attributable to increased screening. The authors suggested a higher skin cancer rate could be explained due to “higher UV exposure”. Read More Charity boss speaks out over ‘traumatic’ encounter with royal aide Ukraine war’s heaviest fight rages in east - follow live Why are wellbeing experts concerned about TikTok’s ‘lazy girl job’ trend? Red flags you might be missing about your child’s online safety Rumer Willis says she is ‘grateful’ to her body following birth of daughter

A fitness expert has slammed Logan Paul and KSI's Prime energy drink and called it their “most profitable scam yet”. James Smith looked at the science behind hydration and claimed that despite the fact the drink is the official hydration sponsor of UFC, Bayern Munich, Arsenal and Barcelona, Paul and KSI “don’t even understand” the concept of hydration. Explaining how rehydration works, Smith said that water and sodium are key to tackling dehydration. He said: “If you’re partaking in a sport [where you] lose loads of water and loads of salt [and you] replenish with just water, over time you’re going to create a negative balance of sodium.” While Smith explained that replenishing electrolytes sodium, potassium, calcium, and magnesium, it was sodium that is the most important to replenish. He then compared Prime’s offering to other leading brands, showing that Prime only has 5mg of sodium. It did however have an impressive 700mg of potassium. Logan Paul's Most Profitable Scam Yet www.youtube.com Powerade, meanwhile, contains 168mg of sodium and 200mg of potassium. “So understanding that when we sweat we lose mostly water and salt, which one of these two, [Prime of Powerade], do you think is going to be superior when it comes to replenishing the sodium that you’re losing?” he asked. It comes after Paul and KSI’s Prime defended the levels of caffeine in its beverages after facing a backlash. Health experts previously called on the US Food and Drug Administration to investigate the energy drink company. A 12 oz can of Prime, which was founded by YouTube stars Logan Paul and KSI, contains 200mg of caffeine, equivalent to about half a dozen Coke cans or nearly two Red Bulls. Sign up to our free Indy100 weekly newsletter Have your say in our news democracy. Click the upvote icon at the top of the page to help raise this article through the indy100 rankings.

England face hosts Australia in the Women’s World Cup semi-finals as the Lionesses come up against not just the Matildas but an entire nation in Sydney. The stage for the latest chapter of England and Australia’s historic rivalry could not be bigger as both teams aim to reach their first-ever Women’s World Cup final, with the hosts gripped by Matildas fever and set for their biggest sporting occasion since the 2000 Olympic Games. The Lionesses rode the wave of home support as they won the Euros last summer but will now look to spoil the party as Sarina Wiegman’s side attempt to make history of their own. England have overcome several challenges to reach the semi-finals and are now faced with their biggest yet as they take on a near-80,000 capacity crowd at Stadium Australia. A place against Spain in Sunday’s final is up for grabs, with ‘La Roja’ defeating Sweden 2-1 yesterday. Follow live updates from England vs Australia in the semi-finals and get all the latest Women’s World Cup odds here Read More How to watch England vs Australia: TV channel and kick-off time for Women’s World Cup semi-final England and Australia’s old rivalry has new stage as World Cup arrives at its biggest moment The Lionesses will need to beat an entire nation in the grip of World Cup fever

Liverpool duo Mohamed Salah and Alisson are subject to interest from clubs in the Saudi Pro League, but the Reds do not intend to sell either of them.

Andrea González aims to be vice-president in Ecuador after her party's presidential candidate was shot dead.

Watch live as supporters arrive at Stadium Australia for the Women’s World Cup semi-final between Australia and England. A place in the showpiece final is up for grabs, in what could be one of the biggest football matches of the year so far. For Australia, they will hope star striker Sam Kerr will be fit enough to feature from the start. She picked up an injury ahead of the tournament and has been limited to appearing as a substitute so far. England boss Sarina Wiegman, though, believes simply nullifying the threat posed by Kerr will not be enough to see the Lionesses through to a first-ever World Cup final. The Australia captain is her country’s leading goal-scorer of either gender but has not yet started a match in the global showpiece after injuring her calf. European champions England take on the Matildas at 11am BST in Sydney, where the majority of the 75,000 in attendance will be backing the co-hosts. Read More ‘Mystic meerkats’ predict winner of England vs Australia World Cup semi-final England forward Rachel Daly among six World Cup stars shortlisted for PFA award England vs Australia: Key stats ahead of crunch World Cup semi-final